Combining CRISPR/Cas9 and rAAV Templates for Efficient Gene Editing (Q38626061)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26540648%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Combining CRISPR/Cas9 and rAAV Templates for Efficient Gene Editing (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26540648%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

0 references

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26540648%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Steven F Dowdy

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26540648%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

publication date

5 November 2015

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26540648%20AND%20SRC:MED&resulttype=core&format=json

Nucleic Acid Therapeutics

29 February 2020

published in

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29 February 2020

volume

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29 February 2020

issue

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29 February 2020

page(s)

287-296

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26540648%20AND%20SRC:MED&resulttype=core&format=json

Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells

29 February 2020

cites work

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

6 September 2017

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In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9

6 September 2017

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6 September 2017

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Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

6 September 2017

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Easy quantitative assessment of genome editing by sequence trace decomposition

6 September 2017

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CRISPR-Cas9 knockin mice for genome editing and cancer modeling

6 September 2017

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Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

6 September 2017

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CRISPR-mediated direct mutation of cancer genes in the mouse liver

6 September 2017

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Low incidence of off-target mutations in individual CRISPR-Cas9 and TALEN targeted human stem cell clones detected by whole-genome sequencing.

6 September 2017

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Unravelling the structural and mechanistic basis of CRISPR-Cas systems

6 September 2017

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Development and applications of CRISPR-Cas9 for genome engineering

6 September 2017

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Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease.

6 September 2017

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Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification

6 September 2017

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Efficient chromosomal gene modification with CRISPR/cas9 and PCR-based homologous recombination donors in cultured Drosophila cells

6 September 2017

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High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells

6 September 2017

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Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype.

6 September 2017

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Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library

6 September 2017

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Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

6 September 2017

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Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos.

6 September 2017

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6 September 2017

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Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system

6 September 2017

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6 September 2017

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Genetic screens in human cells using the CRISPR-Cas9 system

6 September 2017

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6 September 2017

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Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair.

6 September 2017

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Genome engineering using the CRISPR-Cas9 system

6 September 2017

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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

6 September 2017

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Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

6 September 2017

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High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

6 September 2017

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CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

6 September 2017

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CRISPR RNA-guided activation of endogenous human genes

6 September 2017

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DNA targeting specificity of RNA-guided Cas9 nucleases

6 September 2017

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CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

6 September 2017

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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

6 September 2017

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One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

6 September 2017

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6 September 2017

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RNA-programmed genome editing in human cells

6 September 2017

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RNA-guided human genome engineering via Cas9

6 September 2017

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6 September 2017

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Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

6 September 2017

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

6 September 2017

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6 September 2017

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An interdependent metabolic patchwork in the nested symbiosis of mealybugs

6 September 2017

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The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli

6 September 2017

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Evolution and classification of the CRISPR-Cas systems

6 September 2017

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CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III

6 September 2017

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The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA

6 September 2017

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Targeting DNA double-strand breaks with TAL effector nucleases

6 September 2017

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Breaking the code of DNA binding specificity of TAL-type III effectors

6 September 2017

1 reference

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A simple cipher governs DNA recognition by TAL effectors

6 September 2017

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Effect of genome size on AAV vector packaging

6 September 2017

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Adeno-associated virus vector integration

6 September 2017

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Epitope tagging of endogenous genes in diverse human cell lines

6 September 2017

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In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated viruses

6 September 2017

1 reference

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DNA palindromes with a modest arm length of greater, similar 20 base pairs are a significant target for recombinant adeno-associated virus vector integration in the liver, muscles, and heart in mice

6 September 2017

1 reference

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CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

6 September 2017

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A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action

6 September 2017

1 reference

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A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes

6 September 2017

1 reference

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Precise hit: adeno-associated virus in gene targeting

6 September 2017

1 reference

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Large-scale analysis of adeno-associated virus vector integration sites in normal human cells

6 September 2017

1 reference

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Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin

6 September 2017

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Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements

6 September 2017

1 reference

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CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies.

6 September 2017

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Large-scale molecular characterization of adeno-associated virus vector integration in mouse liver

6 September 2017

1 reference

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Enhancing Gene Targeting with Designed Zinc Finger Nucleases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Design, activity, and structure of a highly specific artificial endonuclease

6 September 2017

1 reference

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Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Identification of genes that are associated with DNA repeats in prokaryotes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

A DNA repair system specific for thermophilic Archaea and bacteria predicted by genomic context analysis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Design and packaging of adeno-associated virus gene targeting vectors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Adeno-associated virus vector integration junctions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

6 September 2017

1 reference

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High frequency targeting of genes to specific sites in the mammalian genome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Adeno-associated virus general transduction vectors: analysis of proviral structures

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Genetic and physical analysis of double-strand break repair and recombination in Saccharomyces cerevisiae.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Site-specific recombination determined by I-SceI, a mitochondrial group I intron-encoded endonuclease expressed in the yeast nucleus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Replacement of chromosome segments with altered DNA sequences constructed in vitro

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Adeno-associated virus: a vector system for efficient introduction and integration of DNA into a variety of mammalian cell types

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Homologous recombination in human embryonic stem cells using CRISPR/Cas9 nickase and a long DNA donor template.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Chromosomal effects of adeno-associated virus vector integration

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Biological significance of a family of regularly spaced repeats in the genomes of Archaea, Bacteria and mitochondria.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657517

Gene targeting by homologous recombination in Drosophila

31 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26540648

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Efficient intracellular delivery of native proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26540648

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1089/NAT.2015.0545

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26540648%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26540648%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

26540648

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26540648%20AND%20SRC:MED&resulttype=core&format=json