GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases (Q34454104)

25513782

2 August 2017

title

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases (English)

1 reference

2 August 2017

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11 June 2020

Martin J Aryee

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11 June 2020

J Keith Joung

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11 June 2020

Shengdar Q Tsai

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11 June 2020

Nhu T Nguyen

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11 June 2020

Matthew Liebers

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11 June 2020

Ved V Topkar

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11 June 2020

Vishal Thapar

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11 June 2020

Nicolas Wyvekens

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11 June 2020

Cyd Khayter

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11 June 2020

A John Iafrate

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11 June 2020

Long P Le

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11 June 2020

publication date

16 December 2014

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2 August 2017

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11 June 2020

volume

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issue

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11 June 2020

page(s)

187-197

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Protospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage.

11 June 2020

cites work

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

1 reference

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Development and applications of CRISPR-Cas9 for genome engineering

6 July 2018

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CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences

6 July 2018

1 reference

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Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease.

6 July 2018

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Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

6 July 2018

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Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification

6 July 2018

1 reference

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Targeted genomic rearrangements using CRISPR/Cas technology

6 July 2018

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Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

6 July 2018

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CRISPR-Cas systems for editing, regulating and targeting genomes

6 July 2018

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IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances

6 July 2018

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A multi-split mapping algorithm for circular RNA, splicing, trans-splicing and fusion detection

6 July 2018

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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

6 July 2018

1 reference

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Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems

6 July 2018

1 reference

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Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.

6 July 2018

1 reference

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Genome engineering using the CRISPR-Cas9 system

6 July 2018

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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

6 July 2018

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In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites

6 July 2018

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CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

6 July 2018

1 reference

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High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

6 July 2018

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CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

6 July 2018

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DNA targeting specificity of RNA-guided Cas9 nucleases

6 July 2018

1 reference

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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

6 July 2018

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6 July 2018

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6 July 2018

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RNA-guided editing of bacterial genomes using CRISPR-Cas systems

6 July 2018

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

6 July 2018

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6 July 2018

1 reference

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6 July 2018

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6 July 2018

1 reference

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6 July 2018

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E-CRISP: fast CRISPR target site identification

27 October 2018

1 reference

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High-resolution insertion-site analysis by linear amplification-mediated PCR (LAM-PCR).

27 October 2018

1 reference

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What's changed with genome editing?

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25513782

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Gene editing: how to stay on-target with CRISPR.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25513782

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NBT.3117

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Dimensions Publication ID

11 June 2020

0 references

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11 June 2020

25513782

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