Pages that link to "Q44403034"

The following pages link to Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance (Q44403034):

Displaying 50 items.

• Reverse transcription of the HIV-1 pandemic (Q22242815) (← links)
• Structural basis of HIV-1 resistance to AZT by excision (Q24596976) (← links)
• A mechanistic and structural investigation of modified derivatives of the diaryltriazine class of NNRTIs targeting HIV-1 reverse transcriptase (Q27683249) (← links)
• Mechanistic differences in RNA-dependent DNA polymerization and fidelity between murine leukemia virus and HIV-1 reverse transcriptases (Q28302073) (← links)
• Mechanism of inhibition of the human immunodeficiency virus type 1 reverse transcriptase by d4TTP: an equivalent incorporation efficiency relative to the natural substrate dTTP (Q28343830) (← links)
• Mechanism of action of 1-beta-D-2,6-diaminopurine dioxolane, a prodrug of the human immunodeficiency virus type 1 inhibitor 1-beta-D-dioxolane guanosine (Q28345240) (← links)
• Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism (Q28369244) (← links)
• A mechanism of AZT resistance: an increase in nucleotide-dependent primer unblocking by mutant HIV-1 reverse transcriptase (Q28370658) (← links)
• Nucleotide-dependent conformational change governs specificity and analog discrimination by HIV reverse transcriptase (Q33842807) (← links)
• Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition (Q33896402) (← links)
• Transport, metabolism and elimination mechanisms of anti-HIV agents (Q33933489) (← links)
• Pre-steady-state kinetic analysis of the incorporation of anti-HIV nucleotide analogs catalyzed by human X- and Y-family DNA polymerases (Q34483566) (← links)
• Relationship between 3′-Azido-3′-Deoxythymidine Resistance and Primer Unblocking Activity in Foscarnet-Resistant Mutants of Human Immunodeficiency Virus Type 1 Reverse Transcriptase (Q34996622) (← links)
• Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir (Q35912746) (← links)
• Role of induced fit in limiting discrimination against AZT by HIV reverse transcriptase (Q36053537) (← links)
• Analysis of the Zidovudine Resistance Mutations T215Y, M41L, and L210W in HIV-1 Reverse Transcriptase (Q36290768) (← links)
• Insights into the Molecular Mechanism of Polymerization and Nucleoside Reverse Transcriptase Inhibitor Incorporation by Human PrimPol (Q36439125) (← links)
• Mechanistic and Kinetic Differences between Reverse Transcriptases of Vpx Coding and Non-coding Lentiviruses (Q36444240) (← links)
• NTP-mediated nucleotide excision activity of hepatitis C virus RNA-dependent RNA polymerase (Q36583173) (← links)
• Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase by a stavudine analogue, 4'-ethynyl stavudine triphosphate (Q36703003) (← links)
• Mechanisms of resistance to nucleoside analogue inhibitors of HIV-1 reverse transcriptase. (Q37083800) (← links)
• Relationship between antiviral activity and host toxicity: comparison of the incorporation efficiencies of 2',3'-dideoxy-5-fluoro-3'-thiacytidine-triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondri (Q37120519) (← links)
• DNA polymerases as therapeutic targets (Q37216862) (← links)
• Fidelity and processivity of reverse transcription by the human mitochondrial DNA polymerase (Q38299043) (← links)
• The 3'-azido group is not the primary determinant of 3'-azido-3'-deoxythymidine (AZT) responsible for the excision phenotype of AZT-resistant HIV-1. (Q38324643) (← links)
• Interaction of tRNA-derivatives and oligonucleotide primers with AZT-resistant mutants of HIV-1 reverse transcriptase. (Q38329680) (← links)
• Enhanced binding of azidothymidine-resistant human immunodeficiency virus 1 reverse transcriptase to the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer (Q38336814) (← links)
• K65R and K65A substitutions in HIV-1 reverse transcriptase enhance polymerase fidelity by decreasing both dNTP misinsertion and mispaired primer extension efficiencies (Q38343433) (← links)
• Defining a molecular mechanism of synergy between nucleoside and nonnucleoside AIDS drugs. (Q38346006) (← links)
• Structural determinants in human DNA polymerase gamma account for mitochondrial toxicity from nucleoside analogs. (Q38354757) (← links)
• A new general method for simultaneous fitting of temperature and concentration dependence of reaction rates yields kinetic and thermodynamic parameters for HIV reverse transcriptase specificity (Q38932237) (← links)
• The M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1 impairs rescue of chain-terminated DNA synthesis (Q39590457) (← links)
• ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase (Q39652300) (← links)
• North- and south-bicyclo[3.1.0]hexene nucleosides: the effect of ring planarity on anti-HIV activity. (Q39836948) (← links)
• Structural Aspects of Drug Resistance and Inhibition of HIV-1 Reverse Transcriptase (Q39912641) (← links)
• Role of a dipeptide insertion between codons 69 and 70 of HIV-1 reverse transcriptase in the mechanism of AZT resistance (Q40388003) (← links)
• Pausing kinetics dominates strand-displacement polymerization by reverse transcriptase. (Q41925416) (← links)
• Bifunctional inhibition of human immunodeficiency virus type 1 reverse transcriptase: mechanism and proof-of-concept as a novel therapeutic design strategy (Q42537068) (← links)
• The emergence of different resistance mechanisms toward nucleoside inhibitors is explained by the properties of the wild type HIV-1 reverse transcriptase. (Q43773229) (← links)
• Mechanistic studies to understand the progressive development of resistance in human immunodeficiency virus type 1 reverse transcriptase to abacavir (Q44102100) (← links)
• Molecular mechanism of DApd/DXG against zidovudine- and lamivudine- drug resistant mutants: a molecular modelling approach (Q44142327) (← links)
• Primer unblocking and rescue of DNA synthesis by azidothymidine (AZT)-resistant HIV-1 reverse transcriptase: comparison between initiation and elongation of reverse transcription and between (-) and (+) strand DNA synthesis (Q45177265) (← links)
• The motif D loop of human immunodeficiency virus type 1 reverse transcriptase is critical for nucleoside 5'-triphosphate selectivity (Q45745951) (← links)
• Virologic and enzymatic studies revealing the mechanism of K65R- and Q151M-associated HIV-1 drug resistance towards emtricitabine and lamivudine (Q46914719) (← links)
• Pre-steady-state kinetic studies establish entecavir 5'-triphosphate as a substrate for HIV-1 reverse transcriptase. (Q46930627) (← links)
• The mechano-chemistry of a monomeric reverse transcriptase (Q47145836) (← links)
• The evolution of nucleoside analogue antivirals: A review for chemists and non-chemists. Part 1: Early structural modifications to the nucleoside scaffold. (Q52323442) (← links)
• Poliovirus RNA-dependent RNA polymerase (3D(pol)). Assembly of stable, elongation-competent complexes by using a symmetrical primer-template substrate (sym/sub) (Q73462886) (← links)
• Factors affecting the dimerization of the p66 form of HIV-1 reverse transcriptase (Q73569162) (← links)
• Inhibitors of HIV-1 reverse transcriptase (Q80215893) (← links)