Relationship between antiviral activity and host toxicity: comparison of the incorporation efficiencies of 2',3'-dideoxy-5-fluoro-3'-thiacytidine-triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondri (Q37120519)

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scientific article published on April 2004

Language	Label	Description	Also known as
English	Relationship between antiviral activity and host toxicity: comparison of the incorporation efficiencies of 2',3'-dideoxy-5-fluoro-3'-thiacytidine-triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondri	scientific article published on April 2004

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Relationship between antiviral activity and host toxicity: comparison of the incorporation efficiencies of 2',3'-dideoxy-5-fluoro-3'-thiacytidine-triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondri (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Raymond F. Schinazi

6

object named as

Raymond F Schinazi

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

3

object named as

Suzana M Zorca

1 reference

Europe PubMed Central

18 August 2017

PMC publication ID

Phillip A Furman

7

object named as

Phillip A Furman

1 reference

Europe PubMed Central

18 August 2017

PMC publication ID

Eisuke Murakami

2

object named as

Eisuke Murakami

1 reference

Europe PubMed Central

18 August 2017

PMC publication ID

author name string

Joy Y Feng

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Allison A Johnson

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Kenneth A Johnson

5

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Karen S Anderson

8

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

0 references

publication date

1 April 2004

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

48

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

1300-1306

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Mitochondrial toxicity of nrti antiviral drugs: an integrated cellular perspective

1 reference

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Probing the mechanistic consequences of 5-fluorine substitution on cytidine nucleotide analogue incorporation by HIV-1 reverse transcriptase

1 reference

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Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase.

1 reference

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1 reference

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Toxicity of antiretroviral nucleoside and nucleotide analogues: is mitochondrial toxicity the only mechanism?

1 reference

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Fluorinated nucleosides

1 reference

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1 reference

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Human mitochondrial DNA polymerase holoenzyme: reconstitution and characterization

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1 reference

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Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase

1 reference

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Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism

1 reference

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Comparison of mitochondrial morphology, mitochondrial DNA content, and cell viability in cultured cells treated with three anti-human immunodeficiency virus dideoxynucleosides

1 reference

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Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity

1 reference

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The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

1 reference

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Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes

1 reference

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14 September 2017

Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

1 reference

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Mitochondrial Injury Lessons from the Fialuridine Trial

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29 September 2017

Effect of beta-enantiomeric and racemic nucleoside analogues on mitochondrial functions in HepG2 cells. Implications for predicting drug hepatotoxicity

1 reference

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29 September 2017

Removal of anti-human immunodeficiency virus 2',3'-dideoxynucleoside monophosphates from DNA by a novel human cytosolic 3'-->5' exonuclease

1 reference

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29 September 2017

Expression, purification, and initial kinetic characterization of the large subunit of the human mitochondrial DNA polymerase

1 reference

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27 June 2018

Chemotherapeutic agents for human immunodeficiency virus infection: mechanism of action, pharmacokinetics, metabolism, and adverse reactions

1 reference

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Pre-Steady-State Kinetic Characterization of Wild Type and 3‘-Azido-3‘-deoxythymidine (AZT) Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Implication of RNA Directed DNA Polymerization in the Mechanism of AZT Resistance

1 reference

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Synthesis and antiviral activity of various 3'-azido analogues of pyrimidine deoxyribonucleosides against human immunodeficiency virus (HIV-1, HTLV-III/LAV).

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

Mitochondrial toxicity of nucleoside analogue reverse transcriptase inhibitors: a looming obstacle for long-term antiretroviral therapy?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15047533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.48.4.1300-1306.2004

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

ResearchGate publication ID

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