The 3'-azido group is not the primary determinant of 3'-azido-3'-deoxythymidine (AZT) responsible for the excision phenotype of AZT-resistant HIV-1. (Q38324643)

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English	The 3'-azido group is not the primary determinant of 3'-azido-3'-deoxythymidine (AZT) responsible for the excision phenotype of AZT-resistant HIV-1.	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 September 2017

The 3'-azido group is not the primary determinant of 3'-azido-3'-deoxythymidine (AZT) responsible for the excision phenotype of AZT-resistant HIV-1. (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

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based on heuristic

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based on heuristic

inferred from title

Raymond F. Schinazi

5

object named as

Raymond F Schinazi

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Europe PubMed Central

PubMed publication ID

2 September 2017

Nicolas Sluis-Cremer

1

object named as

Nicolas Sluis-Cremer

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Europe PubMed Central

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2 September 2017

4

object named as

Dianna Koontz

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

author name string

Dominique Arion

2

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Europe PubMed Central

PubMed publication ID

2 September 2017

Urvi Parikh

3

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

John W Mellors

6

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Michael A Parniak

7

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Europe PubMed Central

PubMed publication ID

2 September 2017

language of work or name

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publication date

20 June 2005

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Europe PubMed Central

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2 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

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2 September 2017

280

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Europe PubMed Central

PubMed publication ID

2 September 2017

32

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

29047-29052

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Europe PubMed Central

PubMed publication ID

2 September 2017

Inhibitors of HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Factors contributing to the inhibition of HIV reverse transcriptase by chain-terminating nucleotides in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Molecular mechanisms of HIV-1 resistance to nucleoside reverse transcriptase inhibitors (NRTIs).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Differential removal of thymidine nucleotide analogues from blocked DNA chains by human immunodeficiency virus reverse transcriptase in the presence of physiological concentrations of 2'-deoxynucleoside triphosphates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Site-specific footprinting reveals differences in the translocation status of HIV-1 reverse transcriptase. Implications for polymerase translocation and drug resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Single-step purification of recombinant wild-type and mutant HIV-1 reverse transcriptase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Synthesis and antiviral activity of various 3'-azido analogues of pyrimidine deoxyribonucleosides against human immunodeficiency virus (HIV-1, HTLV-III/LAV).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Resistance of human immunodeficiency virus type 1 to acyclic 6-phenylselenenyl- and 6-phenylthiopyrimidines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Automated minimization of steric clashes in protein structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Single-step kinetics of HIV-1 reverse transcriptase mutants responsible for virus resistance to nucleoside inhibitors zidovudine and 3-TC.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Pre-Steady-State Kinetic Characterization of Wild Type and 3‘-Azido-3‘-deoxythymidine (AZT) Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Implication of RNA Directed DNA Polymerization in the Mechanism of AZT Resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Mechanism by which phosphonoformic acid resistance mutations restore 3'-azido-3'-deoxythymidine (AZT) sensitivity to AZT-resistant HIV-1 reverse transcriptase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Phenotypic and genotypic resistance patterns of HIV-1 isolates derived from individuals treated with didanosine and stavudine.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Genotypic and phenotypic analysis of human immunodeficiency virus type 1 isolates from patients on prolonged stavudine therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Dideoxynucleoside resistance emerges with prolonged zidovudine monotherapy. The RV43 Study Group

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Resistance profile of the human immunodeficiency virus type 1 reverse transcriptase inhibitor abacavir (1592U89) after monotherapy and combination therapy. CNA2001 Investigative Group

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

HIV-1 reverse transcriptase (RT) genotype and susceptibility to RT inhibitors during abacavir monotherapy and combination therapy.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Antiviral activity of tenofovir (PMPA) against nucleoside-resistant clinical HIV samples

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Multiparameter single-molecule fluorescence spectroscopy reveals heterogeneity of HIV-1 reverse transcriptase:primer/template complexes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Physiological concentrations of purines and pyrimidines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

A mechanism of AZT resistance: an increase in nucleotide-dependent primer unblocking by mutant HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503166200

21 January 2018

Identifiers

10.1074/JBC.M503166200

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

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