Virologic and enzymatic studies revealing the mechanism of K65R- and Q151M-associated HIV-1 drug resistance towards emtricitabine and lamivudine (Q46914719)

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scientific article published in January 2006

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English	Virologic and enzymatic studies revealing the mechanism of K65R- and Q151M-associated HIV-1 drug resistance towards emtricitabine and lamivudine	scientific article published in January 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16440988

Virologic and enzymatic studies revealing the mechanism of K65R- and Q151M-associated HIV-1 drug resistance towards emtricitabine and lamivudine (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16440988

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1 reference

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drug resistance

1 reference

based on heuristic

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8

object named as

Bruno Canard

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

author name string

Joy Y Feng

1

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16440988

Florence T Myrick

2

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16440988

Nicolas A Margot

3

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16440988

Gilbert B Mulamba

4

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16440988

Laurence Rimsky

5

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16440988

Katyna Borroto-Esoda

6

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16440988

Boulbaba Selmi

7

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16440988

publication date

1 January 2006

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16440988

Nucleosides, Nucleotides & Nucleic Acids

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16440988

25

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16440988

1

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26 December 2017

http://europepmc.org/abstract/MED/16440988

89-107

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16440988

Rapid changes in human immunodeficiency virus type 1 RNA load and appearance of drug-resistant virus populations in persons treated with lamivudine (3TC).

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Human immunodeficiency virus type-1 reverse transcriptase. Contribution of Met-184 to binding of nucleoside 5'-triphosphate

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Single-step kinetics of HIV-1 reverse transcriptase mutants responsible for virus resistance to nucleoside inhibitors zidovudine and 3-TC.

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Mechanistic studies examining the efficiency and fidelity of DNA synthesis by the 3TC-resistant mutant (184V) of HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

HIV-1 reverse transcriptase (RT) genotype and susceptibility to RT inhibitors during abacavir monotherapy and combination therapy.

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Extended treatment with tenofovir disoproxil fumarate in treatment-experienced HIV-1-infected patients: genotypic, phenotypic, and rebound analyses

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

In vitro selection of mutations in the human immunodeficiency virus type 1 reverse transcriptase that decrease susceptibility to (-)-beta-D-dioxolane-guanosine and suppress resistance to 3'-azido-3'-deoxythymidine

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Molecular mechanisms of resistance to human immunodeficiency virus type 1 with reverse transcriptase mutations K65R and K65R+M184V and their effects on enzyme function and viral replication capacity

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Functional analysis of amino acid residues constituting the dNTP binding pocket of HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Enzymatic characterization of human immunodeficiency virus type 1 reverse transcriptase resistant to multiple 2',3'-dideoxynucleoside 5'-triphosphates

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Prevalence and characteristics of multinucleoside-resistant human immunodeficiency virus type 1 among European patients receiving combinations of nucleoside analogues

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Chemokines and receptors in HIV encephalitis

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Evidence of a role for the Q151L mutation and the viral background in development of multiple dideoxynucleoside-resistant human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides.

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Tenofovir resistance and resensitization

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Steady state and pre-steady state kinetic analyses

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Mechanistic studies comparing the incorporation of (+) and (-) isomers of 3TCTP by HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not.

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Comparative enzymatic study of HIV-1 reverse transcriptase resistant to 2',3'-dideoxynucleotide analogs using the single-nucleotide incorporation assay

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Mechanistic basis for reduced viral and enzymatic fitness of HIV-1 reverse transcriptase containing both K65R and M184V mutations

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

The molecular mechanism of multidrug resistance by the Q151M human immunodeficiency virus type 1 reverse transcriptase and its suppression using alpha-boranophosphate nucleotide analogues

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Relationship between antiviral activity and host toxicity: comparison of the incorporation efficiencies of 2',3'-dideoxy-5-fluoro-3'-thiacytidine-triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondri

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

The 5'-triphosphates of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolane-5-yl]cytosine equally inhibit human immunodeficiency virus type 1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1080%2F15257770500379157

21 January 2018

Identifiers

10.1080/15257770500379157

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16440988

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https://api.fatcat.wiki/v0/release/qrz2qyx3mzf7zfnlf7rwli5yra

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16440988

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