IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances (Q37599944)

21 August 2017

IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances (English)

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21 August 2017

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6 June 2020

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6 June 2020

Monica Gostissa

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6 June 2020

Bjoern Schwer

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6 June 2020

Amelia Chang

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6 June 2020

Junchao Dong

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6 June 2020

Gregory T Marecki

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6 June 2020

Vivian W Choi

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6 June 2020

Ali A Zarrin

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6 June 2020

Frederick W Alt

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6 June 2020

language of work or name

English

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publication date

3 February 2014

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Proceedings of the National Academy of Sciences of the United States of America

21 August 2017

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inferred from page(s)

published in

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6 June 2020

volume

111

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6 June 2020

issue

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6 June 2020

page(s)

2644-2649

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Organization of the mitotic chromosome

6 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Genome engineering using the CRISPR-Cas9 system

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Single-cell Hi-C reveals cell-to-cell variability in chromosome structure

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

RNA-guided human genome engineering via Cas9

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Multiplex genome engineering using CRISPR/Cas systems

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Three-dimensional architecture of the IgH locus facilitates class switch recombination

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Recurrent hemizygous deletions in cancers may optimize proliferative potential

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Spatial partitioning of the regulatory landscape of the X-inactivation centre

23 August 2017

1 reference

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Topological domains in mammalian genomes identified by analysis of chromatin interactions

23 August 2017

1 reference

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Spatial organization of the mouse genome and its role in recurrent chromosomal translocations

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Illegitimate V(D)J recombination involving nonantigen receptor loci in lymphoid malignancy

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

The landscape of somatic copy-number alteration across human cancers

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Comprehensive mapping of long-range interactions reveals folding principles of the human genome

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Evolution of the immunoglobulin heavy chain class switch recombination mechanism

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Influence of switch region length on immunoglobulin class switch recombination

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

53BP1 is required for class switch recombination

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

H2AX may function as an anchor to hold broken chromosomal DNA ends in close proximity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Breakpoint sites disclose the role of the V(D)J recombination machinery in the formation of T-cell receptor (TCR) and non-TCR associated aberrations in T-cell acute lymphoblastic leukemia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Mechanisms of programmed DNA lesions and genomic instability in the immune system.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Classical and alternative end-joining pathways for repair of lymphocyte-specific and general DNA double-strand breaks

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Enhanced intra-switch region recombination during immunoglobulin class switch recombination in 53BP1-/- B cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Antibody class switching mediated by yeast endonuclease-generated DNA breaks.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Chromosomal double-strand breaks introduced in mammalian cells by expression of I-Sce I endonuclease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

Interphase chromosomes undergo constrained diffusional motion in living cells

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

An evolutionarily conserved target motif for immunoglobulin class-switch recombination

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932927

1 September 2018

Identifiers

DOI

10.1073/PNAS.1324176111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24550291%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

0 references

1 reference

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6 June 2020

PubMed publication ID

24550291

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24550291%20AND%20SRC:MED&resulttype=core&format=json