Ending the message: poly(A) signals then and now (Q34213955)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21896654%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

review article

1 reference

title

Ending the message: poly(A) signals then and now (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21896654%20AND%20SRC:MED&resulttype=core&format=json

Nicholas Jarvis Proudfoot

12 February 2020

author

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21896654%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Nick J Proudfoot

1 reference

PubMed publication ID

21896654

31 July 2017

publication date

1 September 2011

1 reference

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12 February 2020

1 reference

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12 February 2020

volume

1 reference

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12 February 2020

issue

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12 February 2020

page(s)

1770-1782

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21896654%20AND%20SRC:MED&resulttype=core&format=json

Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination

12 February 2020

cites work

1 reference

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Unravelling the means to an end: RNA polymerase II transcription termination.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells

5 July 2018

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5 July 2018

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A core complex of CPSF73, CPSF100, and Symplekin may form two different cleavage factors for processing of poly(A) and histone mRNAs

5 July 2018

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DNA damage regulates alternative splicing through inhibition of RNA polymerase II elongation.

5 July 2018

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Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development.

5 July 2018

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Transcriptional termination enhances protein expression in human cells

5 July 2018

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5 July 2018

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5 July 2018

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Metabolism and regulation of canonical histone mRNAs: life without a poly(A) tail

5 July 2018

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5 July 2018

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Conserved motifs in both CPSF73 and CPSF100 are required to assemble the active endonuclease for histone mRNA 3'-end maturation

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease

5 July 2018

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Pause sites promote transcriptional termination of mammalian RNA polymerase II

5 July 2018

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5 July 2018

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Symplekin and multiple other polyadenylation factors participate in 3'-end maturation of histone mRNAs

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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In Vivo Evidence that Defects in the Transcriptional Elongation Factors RPB2, TFIIS, and SPT5 Enhance Upstream Poly(A) Site Utilization

5 July 2018

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A slow RNA polymerase II affects alternative splicing in vivo

5 July 2018

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5 July 2018

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5 July 2018

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Sequence determinants in human polyadenylation site selection

5 July 2018

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5 July 2018

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Oligo(dT) primer generates a high frequency of truncated cDNAs through internal poly(A) priming during reverse transcription

5 July 2018

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5 July 2018

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Multiple transcript cleavage precedes polymerase release in termination by RNA polymerase II

5 July 2018

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Recruitment of a basal polyadenylation factor by the upstream sequence element of the human lamin B2 polyadenylation signal.

5 July 2018

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The carboxyl terminus of vertebrate poly(A) polymerase interacts with U2AF 65 to couple 3'-end processing and splicing

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Levels of polyadenylation factor CstF-64 control IgM heavy chain mRNA accumulation and other events associated with B cell differentiation

5 July 2018

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Co-transcriptional commitment to alternative splice site selection.

5 July 2018

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RNA polymerase II is an essential mRNA polyadenylation factor

5 July 2018

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U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase

5 July 2018

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Mechanism and regulation of mRNA polyadenylation

5 July 2018

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5 July 2018

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5 July 2018

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The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

5 July 2018

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The polyadenylation factor CstF-64 regulates alternative processing of IgM heavy chain pre-mRNA during B cell differentiation

5 July 2018

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Sequences homologous to 5' splice sites are required for the inhibitory activity of papillomavirus late 3' untranslated regions

5 July 2018

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Cleavage site determinants min the mammalian polydenylation signal

5 July 2018

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Upstream sequence elements enhance poly(A) site efficiency of the C2 complement gene and are phylogenetically conserved

5 July 2018

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Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products

5 July 2018

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The sequence 5'-AAUAAA-3'forms parts of the recognition site for polyadenylation of late SV40 mRNAs

5 July 2018

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Polyadenylic Acid Sequences in the Heterogeneous Nuclear RNA and Rapidly-Labeled Polyribosomal RNA of HeLa Cells: Possible Evidence for a Precursor Relationship

5 July 2018

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Translation of globin messenger RNA in a heterologous cell-free system

5 July 2018

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A poly(A) polymerase from calf thymus. Characterization of the reaction product and the primer requirement

5 July 2018

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Use of DNA Polymerase I Primed by a Synthetic Oligonucleotide to Determine a Nucleotide Sequence in Phage f1 DNA

5 July 2018

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Analysis of long pyrimidine polynucleotides in HeLa cell nuclear DNA: absence of polydeoxythymidylate

5 July 2018

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Purification and Sequence of Messenger RNA for Immunoglobulin Light Chains

5 July 2018

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Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Direct determination of DNA nucleotide sequences: structure of a fragment of bacteriophage phiX172 DNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Thalassemia due to a mutation in the cleavage-polyadenylation signal of the human beta-globin gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Multilevel regulation of replication-dependent histone genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Alpha-thalassaemia caused by a poly(A) site mutation reveals that transcriptional termination is linked to 3' end processing in the human alpha 2 globin gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Generation of histone mRNA 3' ends by endonucleolytic cleavage of the pre-mRNA in a snRNP-dependent in vitro reaction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3' termini

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Fine-structure analysis of the processing and polyadenylation region of the herpes simplex virus type 1 thymidine kinase gene by using linker scanning, internal deletion, and insertion mutations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

How RNA polymerase II terminates transcription in higher eukaryotes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Efficiency of utilization of the simian virus 40 late polyadenylation site: effects of upstream sequences

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Patterns of polyadenylation site selection in gene constructs containing multiple polyadenylation signals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Accurate cleavage and polyadenylation of exogenous RNA substrate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Point mutations in AAUAAA and the poly (A) addition site: effects on the accuracy and efficiency of cleavage and polyadenylation in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Involvement of long terminal repeat U3 sequences overlapping the transcription control region in human immunodeficiency virus type 1 mRNA 3' end formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

The human immunodeficiency virus type 1 polyadenylylation signal: a 3' long terminal repeat element upstream of the AAUAAA necessary for efficient polyadenylylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Transcriptional termination between the closely linked human complement genes C2 and factor B: common termination factor for C2 and c-myc?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Preparation and preliminary characterization of purified ovalbumin messenger RNA from the hen oviduct

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

The 3' terminal sequences of human alpha and beta globin messenger RNAs: comparison with rabbit globin messenger RNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

3' non-coding region sequences in eukaryotic messenger RNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

DNA sequencing with chain-terminating inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Sequence analysis of the 3' non-coding regions of rabbit alpha- and beta-globin messenger RNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Amplification and characterization of a β-globin gene synthesized in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Direct interactions between subunits of CPSF and the U2 snRNP contribute to the coupling of pre-mRNA 3' end processing and splicing.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

PACdb: PolyA Cleavage Site and 3'-UTR Database.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Functional interaction of yeast pre-mRNA 3' end processing factors with RNA polymerase II.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Coupling termination of transcription to messenger RNA maturation in yeast.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

The HIV-1 5' LTR poly(A) site is inactivated by U1 snRNP interaction with the downstream major splice donor site.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Alpha-thalassaemia caused by a polyadenylation signal mutation.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Increased efficiency of mRNA 3′ end formation: a new genetic mechanism contributing to hereditary thrombophilia

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175714

Chromatography of 32P-Labelled Oligonucleotides on Thin Layers of DEAE-Cellulose

28 October 2018

1 reference

12 December 2020

Adenine-rich Polymer associated with Rabbit Reticulocyte Messenger RNA

1 reference

12 December 2020

Role of the Conserved AAUAAA Sequence: Four AAUAAA Point Mutants Prevent Messenger RNA 3′ End Formation

1 reference

12 December 2020

A sequence downstream of AAUAAA is required for rabbit β-globin mRNA 3′-end formation

1 reference

12 December 2020

Compensatory mutations suggest that base-pairing with a small nuclear RNA is required to form the 3' end of H3 messenger RNA

1 reference

12 December 2020

Position-dependent sequence elements downstream of AAUAAA are required for efficient rabbit beta-globin mRNA 3' end formation

1 reference

12 December 2020

A functional mRNA polyadenylation signal is required for transcription termination by RNA polymerase II

1 reference

12 December 2020

RNA processing generates the mature 3' end of yeast CYC1 messenger RNA in vitro

1 reference

12 December 2020

Definition of an efficient synthetic poly(A) site

1 reference

12 December 2020

Mutation of the AAUAAA polyadenylation signal depresses in vitro splicing of proximal but not distal introns

1 reference

12 December 2020

Are vertebrate exons scanned during splice-site selection?

1 reference

12 December 2020

Poly(A) site selection in the HIV-1 provirus: inhibition of promoter-proximal polyadenylation by the downstream major splice donor site

1 reference

12 December 2020

Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II

1 reference

12 December 2020

The polyadenylation factor CPSF-73 is involved in histone-pre-mRNA processing

1 reference

12 December 2020

Characteristics of the polyadenylic acid segment associated with messenger ribonucleic acid in mouse sarcoma 180 ascites cells

1 reference

12 December 2020

Evidence that all messenger RNA molecules (except histone messenger RNA) contain poly(A) sequences and that the poly(A) has a nuclear function

1 reference

12 December 2020

A poly(A) polymerase from calf thymus. Purification and properities of the enzyme

1 reference

12 December 2020

Further evidence on the nuclear origin and transfer to the cytoplasm of polyadenylic acid sequences in mammalian cell RNA

1 reference

12 December 2020

Identifiers

DOI

10.1101/GAD.17268411

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21896654%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21896654%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

21896654

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21896654%20AND%20SRC:MED&resulttype=core&format=json