Pause sites promote transcriptional termination of mammalian RNA polymerase II (Q24548945)

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20 January 2020

title

Pause sites promote transcriptional termination of mammalian RNA polymerase II (English)

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20 January 2020

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Nicholas Jarvis Proudfoot

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20 January 2020

Natalia Gromak

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20 January 2020

Steven West

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20 January 2020

language of work or name

English

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publication date

1 May 2006

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Molecular and Cellular Biology

20 January 2020

published in

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volume

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20 January 2020

page(s)

3986-3996

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Human 5' --> 3' exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites

20 January 2020

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1 reference

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MAZ, a zinc finger protein, binds to c-MYC and C2 gene sequences regulating transcriptional initiation and termination

24 March 2017

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CTD-dependent dismantling of the RNA polymerase II elongation complex by the pre-mRNA 3'-end processing factor, Pcf11.

24 March 2017

1 reference

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The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II.

24 March 2017

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Independent functions of yeast Pcf11p in pre-mRNA 3' end processing and in transcription termination

24 March 2017

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Quality control of mRNA 3'-end processing is linked to the nuclear exosome

24 March 2017

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Autocatalytic RNA cleavage in the human beta-globin pre-mRNA promotes transcription termination

24 March 2017

1 reference

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Multiple transcript cleavage precedes polymerase release in termination by RNA polymerase II

24 March 2017

1 reference

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The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

24 March 2017

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Formation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis

24 March 2017

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RNA polymerase II is an essential mRNA polyadenylation factor

24 March 2017

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Delay in synthesis of the 3' splice site promotes trans-splicing of the preceding 5' splice site

7 April 2017

1 reference

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New perspectives on connecting messenger RNA 3' end formation to transcription

27 September 2017

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MAZ elements alter transcription elongation and silencing of the fibroblast growth factor receptor 2 exon IIIb

27 September 2017

1 reference

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Regulation of alternative splicing by a transcriptional enhancer through RNA pol II elongation

27 September 2017

1 reference

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Transcriptional termination and coupled polyadenylation in vitro

27 September 2017

1 reference

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Connecting transcription to messenger RNA processing

27 September 2017

1 reference

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Specific transcriptional pausing activates polyadenylation in a coupled in vitro system

27 September 2017

1 reference

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Inefficient processing impairs release of RNA from the site of transcription

27 September 2017

1 reference

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EM visualization of transcription by RNA polymerase II: downstream termination requires a poly(A) signal but not transcript cleavage.

27 September 2017

1 reference

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Co-transcriptional commitment to alternative splice site selection.

27 September 2017

1 reference

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Intergenic transcription and transinduction of the human β-globin locus

27 September 2017

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MAZ-dependent termination between closely spaced human complement genes

27 September 2017

1 reference

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Products of in vitro cleavage and polyadenylation of simian virus 40 late pre-mRNAs

27 September 2017

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How RNA polymerase II terminates transcription in higher eukaryotes

27 September 2017

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Patterns of polyadenylation site selection in gene constructs containing multiple polyadenylation signals

27 September 2017

1 reference

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A pause site for RNA polymerase II is associated with termination of transcription

27 September 2017

1 reference

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Transcriptional termination between the closely linked human complement genes C2 and factor B: common termination factor for C2 and c-myc?

27 September 2017

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Strong polyadenylation and weak pausing combine to cause efficient termination of transcription in the human Ggamma-globin gene.

27 September 2017

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Poly(A) signals control both transcriptional termination and initiation between the tandem GAL10 and GAL7 genes of Saccharomyces cerevisiae

30 May 2018

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Characterization of the mouse beta maj globin transcription termination region: a spacing sequence is required between the poly(A) signal sequence and multiple downstream termination elements

30 May 2018

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30 May 2018

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Pcf11 is a termination factor in Drosophila that dismantles the elongation complex by bridging the CTD of RNA polymerase II to the nascent transcript

28 November 2018

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Termination of transcription in the mouse alpha-amylase gene Amy-2a occurs at multiple sites downstream of the polyadenylation site

28 November 2018

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12 December 2020

A functional mRNA polyadenylation signal is required for transcription termination by RNA polymerase II

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12 December 2020

Definition of an efficient synthetic poly(A) site

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12 December 2020

5'-exonuclease-2 of Saccharomyces cerevisiae. Purification and features of ribonuclease activity with comparison to 5'-exonuclease-1

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12 December 2020

Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II

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12 December 2020

RNA polymerase II transcription complexes may become arrested if the nascent RNA is shortened to less than 50 nucleotides

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12 December 2020

10.1128/MCB.26.10.3986-3996.2006

Identifiers

DOI

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20 January 2020

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20 January 2020

PubMed publication ID

16648491

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