OPN1MW

Opsin 1, senzitivan na srednje talasne dužine
Identifikatori
Simboli	OPN1MW; CBBM; CBD; GCP
Vanjski ID	OMIM: 303800 HomoloGene: 88332 GeneCards: OPN1MW Gene
Ontologija gena
Molekularna funkcija	• aktivnost rodopsinu-sličnog receptora; • fotoreceptorska aktivnost;
Celularna komponenta	• integralno sa ćelijskom membranom; • membrana;
Biološki proces	• prenos signala; • signalni put G-protein spregnutog receptora; • vizuelna percepcija; • fototransdukcija; • protein-hromofor veza; • respons na stimulus;
Ortolozi

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OPN1MW, zeleno-senzitivni opsin, je protein koji je kod ljudi kodiran OPN1MW genom.^[1]

Povezano

Opsin

Literatura

↑ „Entrez Gene: OPN1MW opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)”. PMID 2652.

Dodatna literatura

Applebury ML, Hargrave PA (1987). „Molecular biology of the visual pigments.”. Vision Res. 26 (12): 1881–95. DOI:10.1016/0042-6989(86)90115-X. PMID 3303660.
Winderickx J, Sanocki E, Lindsey DT, et al. (1993). „Defective colour vision associated with a missense mutation in the human green visual pigment gene.”. Nat. Genet. 1 (4): 251–6. DOI:10.1038/ng0792-251. PMID 1302020.
Neitz J, Neitz M, Jacobs GH (1990). „Analysis of fusion gene and encoded photopigment of colour-blind humans.”. Nature 342 (6250): 679–82. DOI:10.1038/342679a0. PMID 2574415.
Nathans J, Thomas D, Hogness DS (1986). „Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.”. Science 232 (4747): 193–202. DOI:10.1126/science.2937147. PMID 2937147.
Li ZY, Kljavin IJ, Milam AH (1995). „Rod photoreceptor neurite sprouting in retinitis pigmentosa.”. J. Neurosci. 15 (8): 5429–38. PMID 7643192.
Ladekjaer-Mikkelsen AS, Rosenberg T, Jørgensen AL (1996). „A new mechanism in blue cone monochromatism.”. Hum. Genet. 98 (4): 403–8. DOI:10.1007/s004390050229. PMID 8792812.
Ferreira PA, Nakayama TA, Pak WL, Travis GH (1996). „Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.”. Nature 383 (6601): 637–40. DOI:10.1038/383637a0. PMID 8857542.
Vissers PM, Bovee-Geurts PH, Portier MD, et al. (1998). „Large-scale production and purification of the human green cone pigment: characterization of late photo-intermediates.”. Biochem. J.. 330 (Pt 3): 1201–8. PMC 1219262. PMID 9494086.
Bernstein SL, Wong P (1998). „Regional expression of disease-related genes in human and monkey retina.”. Mol. Vis. 4: 24. PMID 9815288.
Hayashi T, Motulsky AG, Deeb SS (1999). „Position of a 'green-red' hybrid gene in the visual pigment array determines colour-vision phenotype.”. Nat. Genet. 22 (1): 90–3. DOI:10.1038/8798. PMID 10319869.
Ueyama H, Kuwayama S, Imai H, et al. (2002). „Novel missense mutations in red/green opsin genes in congenital color-vision deficiencies.”. Biochem. Biophys. Res. Commun. 294 (2): 205–9. DOI:10.1016/S0006-291X(02)00458-8. PMID 12051694.
Zhu X, Brown B, Li A, et al. (2003). „GRK1-dependent phosphorylation of S and M opsins and their binding to cone arrestin during cone phototransduction in the mouse retina.”. J. Neurosci. 23 (14): 6152–60. PMID 12853434.
Bonilha VL, Hollyfield JG, Grover S, Fishman GA (2005). „Abnormal distribution of red/green cone opsins in a patient with an autosomal dominant cone dystrophy.”. Ophthalmic Genet. 26 (2): 69–76. DOI:10.1080/13816810590968041. PMID 16020309.

Spoljašnje veze

Crveno-zeleni defekti vida

[entrez-1] „Entrez Gene: OPN1MW opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)”. PMID 2652.

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