GPR63
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| G protein-spregnuti receptor 63 | |||||||||||
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| Identifikatori | |||||||||||
| Simboli | GPR63; PSP24(beta); PSP24B | ||||||||||
| Vanjski ID | OMIM: 606915 MGI: 2135884 HomoloGene: 12759 IUPHAR: GPR63 GeneCards: GPR63 Gene | ||||||||||
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| Pregled RNK izražavanja | |||||||||||
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| podaci | |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 81491 | 81006 | |||||||||
| Ensembl | ENSG00000112218 | ENSMUSG00000040372 | |||||||||
| UniProt | Q9BZJ6 | Q8BZ93 | |||||||||
| RefSeq (mRNA) | NM_030784 | NM_030733 | |||||||||
| RefSeq (protein) | NP_110411 | NP_109658 | |||||||||
| Lokacija (UCSC) | Chr 6: 97.35 - 97.39 Mb | Chr 4: 25.06 - 25.1 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
GPR63, G protein-spregnuti receptor 63, je protein koji je kod čoveka kodiran GPR63 genom.[1]
G protein spregnuti receptori sadrže sedam transmembranskih domena i prenose ekstracelularne signale kroz heterotrimerne G proteine.[1]
- Kawasawa Y, Kume K, Nakade S, et al. (2000). „Brain-specific expression of novel G-protein-coupled receptors, with homologies to Xenopus PSP24 and human GPR45.”. Biochem. Biophys. Res. Commun. 276 (3): 952–6. DOI:10.1006/bbrc.2000.3569. PMID 11027574.
- Kawasawa Y, Kume K, Izumi T, Shimizu T (2000). „Mammalian PSP24s (alpha and beta isoforms) are not responsive to lysophosphatidic acid in mammalian expression systems.”. Biochem. Biophys. Res. Commun. 276 (3): 957–64. DOI:10.1006/bbrc.2000.3570. PMID 11027575.
- Lee DK, George SR, Cheng R, et al. (2001). „Identification of four novel human G protein-coupled receptors expressed in the brain.”. Brain Res. Mol. Brain Res. 86 (1–2): 13–22. DOI:10.1016/S0169-328X(00)00242-4. PMID 11165367.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Niedernberg A, Tunaru S, Blaukat A, et al. (2004). „Sphingosine 1-phosphate and dioleoylphosphatidic acid are low affinity agonists for the orphan receptor GPR63”. Cell. Signal. 15 (4): 435–46. DOI:10.1016/S0898-6568(02)00119-5. PMID 12618218.
- Mungall AJ, Palmer SA, Sims SK, et al. (2003). „The DNA sequence and analysis of human chromosome 6”. Nature 425 (6960): 805–11. DOI:10.1038/nature02055. PMID 14574404.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.