Dokozatetraenoinska kiselina
| Adrenska kiselina | |||
|---|---|---|---|
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| IUPAC ime |
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| Identifikacija | |||
| CAS registarski broj | 28874-58-0 | ||
| PubChem[1][2] | 5497181 | ||
| ChemSpider[3] | 4593749 | ||
| Jmol-3D slike | Slika 1 | ||
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| Svojstva | |||
| Molekulska formula | C22H36O2 | ||
| Molarna masa | 332,5 g/mol | ||
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Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala | |||
| Infobox references | |||
Dokozatetraenoinska kiselina označava svaku nerazgranatu 22:4 masnu kiselinu.
Jedan izomer o posebnog interesa je: sve-cis-7,10,13,16-dokozatetraenoinska kiselina. Ona je ω-6 masna kiselina sa trivijalnim imenom adrenska kiselina. Ova polinezasićena masna kiselina se javlja u prirodi. Ona se formira putem elongacije arahidonske kiseline dvougljeničnim segmentima. Ona je jedna od najobilnije zastupljenih masnih kiselina u ljudskom mozgu.[4]
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.
- ↑ Martinez M (1992). „Tissue levels of polyunsaturated fatty acids during early human development”. J Pediatr 120 (4 Pt 2): S129–38. DOI:10.1016/S0022-3476(05)81247-8. PMID 1532827.
- Ferretti, A., Flanagan, V.P. Mass spectrometric evidence for the conversion of exogenous adrenate to dihomo-prostaglandins by seminal vesicle cyclo-oxygenase. A comparative study of two animal species. J Chromatogr 383 241-250 (1986).
- Sprecher, H., VanRollins, M., Sun, F., et al. Dihomo-prostaglandins and -thromboxane. A prostaglandin family from adrenic acid that may be preferentially synthesized in the kidney. J Biol Chem 257 3912-3918 (1982).
