Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics. (Q52606339)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29618808%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

title

Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics (English)

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22 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29618808%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Mark A Petersen

1 reference

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22 March 2020

Jae Kyu Ryu

series ordinal

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22 March 2020

language of work or name

English

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publication date

5 April 2018

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Nature Reviews Neuroscience

22 March 2020

published in

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22 March 2020

volume

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22 March 2020

issue

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22 March 2020

page(s)

283-301

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Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease

22 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

TREM2 Variants in Alzheimer's Disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

The blood-brain barrier in health and chronic neurodegenerative disorders

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrinogen signal transduction as a mediator and therapeutic target in inflammation: lessons from multiple sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrinogen as a key regulator of inflammation in disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

The fibrin-derived gamma377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGF-beta after vascular damage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrin inhibits peripheral nerve remyelination by regulating Schwann cell differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Current concepts of blood-brain barrier development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Brain barriers: Crosstalk between complex tight junctions and adherens junctions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Stepwise recruitment of transcellular and paracellular pathways underlies blood-brain barrier breakdown in stroke

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Establishment and Dysfunction of the Blood-Brain Barrier

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Tissue factor contributes to microvascular defects after focal cerebral ischemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Nervous system pathology: the fibrin perspective

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Astrocyte-endothelial interactions at the blood-brain barrier

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Cerebrovascular and blood-brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Human plasma fibrinogen is synthesized in the liver

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

31 March 2020

Fibrinogen and fibrin.

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Molecular mechanisms affecting fibrin structure and stability

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrinogen and fibrin structure and functions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

A model of fibrin formation based on crystal structures of fibrinogen and fibrin fragments complexed with synthetic peptides

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Dissecting clot retraction and platelet aggregation. Clot retraction does not require an intact fibrinogen gamma chain C terminus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Structure and function of the plasminogen/plasmin system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Breaking boundaries-coagulation and fibrinolysis at the neurovascular interface

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

The axonally secreted serine proteinase inhibitor, neuroserpin, inhibits plasminogen activators and plasmin but not thrombin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrin structure and wound healing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Accelerated skin wound healing in plasminogen activator inhibitor-1-deficient mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Loss of fibrinogen rescues mice from the pleiotropic effects of plasminogen deficiency.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Impaired wound healing in mice with a disrupted plasminogen gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

A detailed consideration of a principal domain of vertebrate fibrinogen and its relatives

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Correlating structure and function during the evolution of fibrinogen-related domains

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

A novel human serum lectin with collagen- and fibrinogen-like domains that functions as an opsonin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Tenascins and the importance of adhesion modulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

The primary role of fibrinogen-related proteins in invertebrates is defense, not coagulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Scabrous complexes with Notch to mediate boundary formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Multiple Sclerosis Pathology: Evolution of Pathogenetic Concepts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Heterogeneity of multiple sclerosis pathogenesis: implications for diagnosis and therapy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Multiple sclerosis: lessons from neuropathology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Multiple sclerosis: serial study of gadolinium-enhanced MR imaging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Serial gadolinium enhanced magnetic resonance imaging in multiple sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis. Pathogenetic and clinical implications

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

MRI contrast uptake in new lesions in relapsing-remitting MS followed at weekly intervals.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Initial investigation of the blood-brain barrier in MS lesions at 7 tesla

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Evolution of the blood-brain barrier in newly forming multiple sclerosis lesions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Inflammatory central nervous system demyelination: correlation of magnetic resonance imaging findings with lesion pathology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Blood-brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Tight junctional abnormality in multiple sclerosis white matter affects all calibres of vessel and is associated with blood-brain barrier leakage and active demyelination.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Blood-brain barrier abnormalities in longstanding multiple sclerosis lesions. An immunohistochemical study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrin(ogen) and neurodegeneration in the progressive multiple sclerosis cortex.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Plasminogen activators in multiple sclerosis lesions: implications for the inflammatory response and axonal damage.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Impaired fibrinolysis in multiple sclerosis: a role for tissue plasminogen activator inhibitors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

The application of multifactorial cluster analysis in the staging of plaques in early multiple sclerosis. Identification and characterization of the primary demyelinating lesion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Immunohistochemical study of vascular injury in acute multiple sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

The morbid anatomy of the demyelinative disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

The formation of inflammatory demyelinated lesions in cerebral white matter.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Sequence gamma 377-395(P2), but not gamma 190-202(P1), is the binding site for the alpha MI-domain of integrin alpha M beta 2 in the gamma C-domain of fibrinogen

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Regulated unmasking of the cryptic binding site for integrin alpha M beta 2 in the gamma C-domain of fibrinogen

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Cleavage of fibrinogen by proteinases elicits allergic responses through Toll-like receptor 4.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

CD11b/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Dual receptors and distinct pathways mediate interleukin-1 receptor-associated kinase degradation in response to lipopolysaccharide. Involvement of CD14/TLR4, CR3, and phosphatidylinositol 3-kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrinogen depleting agent batroxobin has a beneficial effect on experimental autoimmune encephalomyelitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Leukocyte engagement of fibrin(ogen) via the integrin receptor alphaMbeta2/Mac-1 is critical for host inflammatory response in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrin(ogen)-alpha M beta 2 interactions regulate leukocyte function and innate immunity in vivo.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Alzheimer mechanisms and therapeutic strategies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

The pathobiology of vascular dementia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Mixed brain pathologies account for most dementia cases in community-dwelling older persons

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Relation of cerebral vessel disease to Alzheimer's disease dementia and cognitive function in elderly people: a cross-sectional study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Blood-brain barrier impairment in Alzheimer disease: stability and functional significance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Dementia in 2011: Microbleeds in dementia--singing a different ARIA.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Serial susceptibility weighted MRI measures brain iron and microbleeds in dementia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Microvascular pathology in the aging human brain: evidence that senile plaques are sites of microhaemorrhages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Alzheimer disease makes new blood contacts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

The APOE ɛ4/ɛ4 genotype potentiates vascular fibrin(ogen) deposition in amyloid-laden vessels in the brains of Alzheimer's disease patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer's disease brain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Cyclooxygenase-2-positive macrophages infiltrate the Alzheimer's disease brain and damage the blood-brain barrier

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Differing associations between Aβ accumulation, hypoperfusion, blood-brain barrier dysfunction and loss of PDGFRB pericyte marker in the precuneus and parietal white matter in Alzheimer's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Deficiency in mural vascular cells coincides with blood-brain barrier disruption in Alzheimer's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Plasma fibrinogen is associated with cognitive decline and risk for dementia in patients with mild cognitive impairment.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrinogen is associated with an increased risk of Alzheimer disease and vascular dementia.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Alzheimer's disease: A matter of blood-brain barrier dysfunction?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

FTY720 Attenuates Infection-Induced Enhancement of Aβ Accumulation in APP/PS1 Mice by Modulating Astrocytic Activation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

A novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer's disease mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Regional early and progressive loss of brain pericytes but not vascular smooth muscle cells in adult mice with disrupted platelet-derived growth factor receptor-β signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Apolipoprotein E controls cerebrovascular integrity via cyclophilin A.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Relevance of abeta1-42 intrahippocampal injection as an animal model of inflamed Alzheimer's disease brain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Thrombin, a mediator of cerebrovascular inflammation in AD and hypoxia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Enoxaparin treatment administered at both early and late stages of amyloid β deposition improves cognition of APPswe/PS1dE9 mice with differential effects on brain Aβ levels

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Peripheral treatment with enoxaparin, a low molecular weight heparin, reduces plaques and beta-amyloid accumulation in a mouse model of Alzheimer's disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Alzheimer's disease peptide beta-amyloid interacts with fibrinogen and induces its oligomerization.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

The Alzheimer's disease peptide β-amyloid promotes thrombin generation through activation of coagulation factor XII.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Aβ delays fibrin clot lysis by altering fibrin structure and attenuating plasminogen binding to fibrin.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Tissue plasminogen activator arrests Alzheimer's disease pathogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrinogen-Derived γ377-395 Peptide Improves Cognitive Performance and Reduces Amyloid-β Deposition, without Altering Inflammation, in AβPP/PS1 Mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Depletion of coagulation factor XII ameliorates brain pathology and cognitive impairment in Alzheimer disease mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Lack of Widespread BBB Disruption in Alzheimer's Disease Models: Focus on Therapeutic Antibodies.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

White matter hyperintensities are seen only in GRN mutation carriers in the GENFI cohort

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Frontotemporal lobar degeneration FTLD-tau: preclinical lesions, vascular, and Alzheimer-related co-pathologies.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Blood-spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Inflammation and neurovascular changes in amyotrophic lateral sclerosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Blood-brain barrier dysfunction in parkinsonian midbrain in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Increased blood-cerebrospinal fluid transfer of albumin in advanced Parkinson's disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Striatal blood-brain barrier permeability in Parkinson's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Blood-brain barrier breakdown as a therapeutic target in traumatic brain injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Blood-brain barrier pathophysiology in traumatic brain injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Blood-brain barrier disruption in post-traumatic epilepsy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Focal cortical dysfunction and blood-brain barrier disruption in patients with Postconcussion syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Pericytes regulate the blood-brain barrier

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Remyelination in the CNS: from biology to therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Myelin regeneration: a recapitulation of development?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Glial development: the crossroads of regeneration and repair in the CNS

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

BMP signalling in skeletal development, disease and repair.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Extrinsic regulation of pluripotent stem cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Oligodendrocyte maturation is inhibited by bone morphogenetic protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Transgenic overexpression of BMP4 increases astroglial and decreases oligodendroglial lineage commitment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

The toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Maturation-dependent vulnerability of oligodendrocytes to oxidative stress-induced death caused by glutathione depletion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Vulnerability of oligodendroglia to glutamate: pharmacology, mechanisms, and prevention

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrinogen in the Nervous System: Glia Beware.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

A bloody brake on myelin repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Tissue plasminogen activator-mediated fibrinolysis protects against axonal degeneration and demyelination after sciatic nerve injury.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

The extracellular matrix affects axonal regeneration in peripheral neuropathies.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Exogenous tissue plasminogen activator enhances peripheral nerve regeneration and functional recovery after injury in mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrin is a regulator of Schwann cell migration after sciatic nerve injury in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrinogen inhibits neurite outgrowth via beta 3 integrin-mediated phosphorylation of the EGF receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Embolus extravasation is an alternative mechanism for cerebral microvascular recanalization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Optical imaging of fibrin deposition to elucidate participation of mast cells in foreign body responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Direct Imaging of Cerebral Thromboemboli Using Computed Tomography and Fibrin-targeted Gold Nanoparticles

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

EP-2104R: a fibrin-specific gadolinium-Based MRI contrast agent for detection of thrombus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Multisite Thrombus Imaging and Fibrin Content Estimation With a Single Whole-Body PET Scan in Rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

In vivo fluorescence imaging of atherosclerotic plaques with activatable cell-penetrating peptides targeting thrombin activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Thrombin activity associated with neuronal damage during acute focal ischemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Ratiometric activatable cell-penetrating peptides provide rapid in vivo readout of thrombin activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Early detection of thrombin activity in neuroinflammatory disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrinogen gamma-A chain precursor in CSF: a candidate biomarker for Alzheimer's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Multiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Identification of SPARC-like 1 protein as part of a biomarker panel for Alzheimer's disease in cerebrospinal fluid

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Plasma biomarkers of brain atrophy in Alzheimer's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Prognostic polypeptide blood plasma biomarkers of Alzheimer's disease progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Proteome study of human cerebrospinal fluid following traumatic brain injury indicates fibrin(ogen) degradation products as trauma-associated markers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Elevated fibrinogen levels in neuromyelitis optica is associated with severity of disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Prothrombin and factor X are elevated in multiple sclerosis patients.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Activation of the factor XII-driven contact system in Alzheimer's disease patient and mouse model plasma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Increased cerebrospinal fluid fibrinogen in major depressive disorder.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

The blood-brain barrier in psychosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Disruption in the Blood-Brain Barrier: The Missing Link between Brain and Body Inflammation in Bipolar Disorder?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Blood-spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Vascular pathology in multiple sclerosis: reframing pathogenesis around the blood-brain barrier.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

The impact of interferon-beta treatment on the blood-brain barrier

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Dimethyl fumarate attenuates cerebral edema formation by protecting the blood-brain barrier integrity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fingolimod prevents blood-brain barrier disruption induced by the sera from patients with multiple sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Laquinimod enhances central nervous system barrier functions.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Statins reduce human blood-brain barrier permeability and restrict leukocyte migration: relevance to multiple sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MS-STAT): a randomised, placebo-controlled, phase 2 trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

The Alzheimer's disease peptide β-amyloid promotes thrombin generation through activation of coagulation factor XII: reply.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

A possible new role for Aβ in vascular and inflammatory dysfunction in Alzheimer's disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Evidence of persistent blood-brain barrier abnormalities in chronic-progressive multiple sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Suppression of cell-transferred experimental autoimmune encephalomyelitis in defibrinated Lewis rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrin deposition in the central nervous system correlates with the degree of Theiler's murine encephalomyelitis virus-induced demyelinating disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Conformational changes upon conversion of fibrinogen into fibrin. The mechanisms of exposure of cryptic sites

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Affinity of fibronectin to collagens of different genetic types and to fibrinogen

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Fibrinogen binds to integrin alpha(5)beta(1) via the carboxyl-terminal RGD site of the Aalpha-chain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

alphaVbeta8 integrin is a Schwann cell receptor for fibrin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Interaction of fibrin(ogen) with the endothelial cell receptor VE-cadherin: mapping of the receptor-binding site in the NH2-terminal portions of the fibrin beta chains

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Identification of VLDLR as a novel endothelial cell receptor for fibrin that modulates fibrin-dependent transendothelial migration of leukocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Structural recognition of a novel fibrinogen gamma chain sequence (117-133) by intercellular adhesion molecule-1 mediates leukocyte-endothelium interaction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Protective effects of Batroxobin on spinal cord injury in rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Persistent endothelial abnormalities and blood-brain barrier leak in primary and secondary progressive multiple sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Dysferlin is a new marker for leaky brain blood vessels in multiple sclerosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Pericyte degeneration causes white matter dysfunction in the mouse central nervous system.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Blood-brain barrier damage in acute multiple sclerosis plaques. An immunocytological study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

New insight into Alzheimer disease: demonstration of fibrin(ogen)-serum albumin insoluble deposits in brain tissue

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Evidence of blood-brain barrier dysfunction in human cerebral malaria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

Activation of the contact system in cerebrospinal fluid of patients with Alzheimer disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2018.13

7 January 2021

inferred from DOI database lookup

Experimental allergic encephalomyelitis: role of fibrin deposition in immunopathogenesis of inflammation in rats

1 reference

12 December 2020

Interaction of integrins alpha v beta 3 and glycoprotein IIb-IIIa with fibrinogen. Differential peptide recognition accounts for distinct binding sites

1 reference

12 December 2020

Fibrin deposition in primary and metastatic human brain tumours

1 reference

12 December 2020

Impaired platelet aggregation and sustained bleeding in mice lacking the fibrinogen motif bound by integrin alpha IIb beta 3.

1 reference

12 December 2020

Characterization of human fibroleukin, a fibrinogen-like protein secreted by T lymphocytes

1 reference

12 December 2020

Involvement of tissue plasminogen activator in onset and effector phases of experimental allergic encephalomyelitis

1 reference

12 December 2020

Blood-brain barrier permeability precedes senile plaque formation in an Alzheimer disease model

1 reference

12 December 2020

Fibrin mechanisms and functions in nervous system pathology

1 reference

12 December 2020

BMPs: from bone to body morphogenetic proteins

1 reference

12 December 2020

Blood-Brain Barrier Disruption Is an Early Event That May Persist for Many Years After Traumatic Brain Injury in Humans.

1 reference

12 December 2020

Blood protein predictors of brain amyloid for enrichment in clinical trials?

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRN.2018.13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29618808%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29618808%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

PubMed publication ID

29618808

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29618808%20AND%20SRC:MED&resulttype=core&format=json