Extrinsic regulation of pluripotent stem cells (Q37763846)

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scientific article published on June 2010

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English	Extrinsic regulation of pluripotent stem cells	scientific article published on June 2010

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instance of

scholarly article

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Europe PubMed Central

PubMed publication ID

20535200

retrieved

22 August 2017

review article

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Europe PubMed Central

title

Extrinsic regulation of pluripotent stem cells (English)

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Europe PubMed Central

PubMed publication ID

20535200

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22 August 2017

main subject

pluripotency

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based on heuristic

inferred from title

author

Martin Pera

series ordinal

1

object named as

Martin F Pera

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Europe PubMed Central

PubMed publication ID

20535200

retrieved

22 August 2017

author name string

Patrick P L Tam

series ordinal

2

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Europe PubMed Central

PubMed publication ID

20535200

retrieved

22 August 2017

language of work or name

English

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publication date

1 June 2010

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Europe PubMed Central

PubMed publication ID

20535200

retrieved

22 August 2017

published in

Nature

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stated in

Europe PubMed Central

PubMed publication ID

20535200

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22 August 2017

volume

465

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stated in

Europe PubMed Central

PubMed publication ID

20535200

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22 August 2017

issue

7299

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Europe PubMed Central

PubMed publication ID

20535200

retrieved

22 August 2017

page(s)

713-720

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Europe PubMed Central

PubMed publication ID

20535200

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22 August 2017

cites work

Preimplantation human embryos and embryonic stem cells show comparable expression of stage-specific embryonic antigens

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

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The Grb2/Mek pathway represses Nanog in murine embryonic stem cells

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

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GDF3 at the crossroads of TGF-beta signaling

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for Wnt3 in vertebrate axis formation

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and potential role of fibroblast growth factor 2 and its receptors in human embryonic stem cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

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inferred from PubMed ID database lookup

Gene function in mouse embryogenesis: get set for gastrulation

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

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Embryonic stem-cell culture as a tool for developmental cell biology.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

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Progressive lineage analysis by cell sorting and culture identifies FLK1+VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

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Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

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inferred from PubMed ID database lookup

TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of germ-line-competent embryonic stem (ES) cells using differentiation inhibiting activity

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryonic stem cell lines derived from human blastocysts

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Derivation of neural precursors from human embryonic stem cells in the presence of noggin.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wnt/beta-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

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The 'stem cell' concept: is it holding us back?

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment in culture of pluripotential cells from mouse embryos

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Capturing pluripotency

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metastable pluripotent states in NOD-mouse-derived ESCs

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diversity of germ layer and axis formation among mammals

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The growth factor environment defines distinct pluripotent ground states in novel blastocyst-derived stem cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oct-4 mRNA and protein expression during human preimplantation development

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption in murine cells reveals variable requirement for Smad4 in transforming growth factor beta-related signaling.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryo

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of mRNAs for DNA methyltransferases and methyl-CpG-binding proteins in the human female germ line, preimplantation embryos, and embryonic stem cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

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Formation of a primitive ectoderm like cell population, EPL cells, from ES cells in response to biologically derived factors

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of human embryonic stem cell lines by the International Stem Cell Initiative

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induced pluripotent stem cell lines derived from human somatic cells

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niche-mediated control of human embryonic stem cell self-renewal and differentiation

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of caspase-mediated anoikis is critical for basic fibroblast growth factor-sustained culture of human pluripotent stem cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

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An autogeneic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

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Molecular analysis of LEFTY-expressing cells in early human embryoid bodies

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mouse embryo autonomously acquires anterior-posterior polarity at implantation

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

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Essential roles of sphingosine-1-phosphate and platelet-derived growth factor in the maintenance of human embryonic stem cells

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

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Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

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BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

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Cellular differentiation hierarchies in normal and culture-adapted human embryonic stem cells

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

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Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

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Isolation and characterization of a multipotent clone of human embryonal carcinoma cells.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

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Human embryonic stem cells: prospects for development

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

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Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

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Phosphoproteomic analysis of human embryonic stem cells

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

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Unraveling epigenetic regulation in embryonic stem cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

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A continuum of cell states spans pluripotency and lineage commitment in human embryonic stem cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

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Klf4 reverts developmentally programmed restriction of ground state pluripotency

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

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Development of serum-free culture systems for human embryonic stem cells

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

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Derivation of pluripotent epiblast stem cells from mammalian embryos

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Promotion of trophoblast stem cell proliferation by FGF4

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ground state of embryonic stem cell self-renewal

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

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NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary differentiation in the human blastocyst: comparative molecular portraits of inner cell mass and trophectoderm cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GDF3, a BMP inhibitor, regulates cell fate in stem cells and early embryos

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of human embryonic stem cell surface markers by combined membrane-polysome translation state array analysis and immunotranscriptional profiling

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional analysis of early lineage commitment in human embryonic stem cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-apoptotic effect of sphingosine-1-phosphate and platelet-derived growth factor in human embryonic stem cells.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basic fibroblast growth factor activates ERK and induces c-fos in human embryonic stem cell line MizhES1.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A meta-analysis of human embryonic stem cells transcriptome integrated into a web-based expression atlas.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GDF3 is a BMP inhibitor that can activate Nodal signaling only at very high doses

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts

1 reference

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https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human STELLAR, NANOG, and GDF3 genes are expressed in pluripotent cells and map to chromosome 12p13, a hotspot for teratocarcinoma

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New cell lines from mouse epiblast share defining features with human embryonic stem cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MEK/ERK signaling contributes to the maintenance of human embryonic stem cell self-renewal

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activin/Nodal signalling maintains pluripotency by controlling Nanog expression.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nodal signaling: developmental roles and regulation.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The transcriptional foundation of pluripotency

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BMP-11 and myostatin support undifferentiated growth of human embryonic stem cells in feeder-free cultures

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human embryonic stem cells.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KLF4 and PBX1 directly regulate NANOG expression in human embryonic stem cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activin-Nodal signaling is involved in propagation of mouse embryonic stem cells.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of the FGF-4 gene in embryonic stem cells alters the growth and/or the survival of their early differentiated progeny

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naive and primed pluripotent states

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defined culture conditions of human embryonic stem cells

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20535200

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12 December 2020

based on heuristic

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Identifiers

DOI

10.1038/NATURE09228

1 reference

stated in

Europe PubMed Central

PubMed publication ID

20535200

retrieved

22 August 2017

PubMed publication ID

20535200

1 reference

stated in

Europe PubMed Central

PubMed publication ID

20535200

retrieved

22 August 2017

 

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