Cerebrovascular and blood-brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology (Q45305215)

11 December 2017

title

Cerebrovascular and blood-brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology (English)

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11 December 2017

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9 June 2020

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9 June 2020

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9 June 2020

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9 June 2020

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9 June 2020

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9 June 2020

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9 June 2020

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9 June 2020

Janelle Drouin-Ouellet

object named as

Janelle Drouin-Ouellet

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Francesca Cicchetti

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Penny A Gowland

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Marie Lagacé

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9 June 2020

Martine Saint-Pierre

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9 June 2020

Richard J Dury

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9 June 2020

Wael Alata

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9 June 2020

Sarah L Mason

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9 June 2020

publication date

9 April 2015

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11 December 2017

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9 June 2020

volume

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9 June 2020

issue

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9 June 2020

page(s)

160-177

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Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

9 June 2020

cites work

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Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

21 January 2018

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Protein misfolding, amyloid formation, and neurodegeneration: a critical role for molecular chaperones?

21 January 2018

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An in vitro perspective on the molecular mechanisms underlying mutant huntingtin protein toxicity

21 January 2018

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Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms

21 January 2018

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Genetic manipulations of mutant huntingtin in mice: new insights into Huntington's disease pathogenesis

21 January 2018

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Mutant huntingtin is present in neuronal grafts in Huntington disease patients

21 January 2018

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Mutant huntingtin fragmentation in immune cells tracks Huntington's disease progression

21 January 2018

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Aβ₁₋₄₂-RAGE interaction disrupts tight junctions of the blood-brain barrier via Ca²⁺-calcineurin signaling.

21 January 2018

1 reference

Striatal allografts in patients with Huntington's disease: impact of diminished astrocytes and vascularization on graft viability.

21 January 2018

1 reference

Age-dependent neurovascular abnormalities and altered microglial morphology in the YAC128 mouse model of Huntington disease

21 January 2018

1 reference

Neurovascular abnormalities in humans and mice with Huntington's disease

21 January 2018

1 reference

Single photon emission computed tomographic blood flow and magnetic resonance volume imaging of basal ganglia in Huntington's disease

21 January 2018

1 reference

Reduced basal ganglia blood flow and volume in pre-symptomatic, gene-tested persons at-risk for Huntington's disease

21 January 2018

1 reference

Reduced regional cerebral blood flow in Huntington's disease studied by SPECT.

21 January 2018

1 reference

The combined use of positron emission tomography and DNA polymorphisms for preclinical detection of Huntington's disease

21 January 2018

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CAG repeat number governs the development rate of pathology in Huntington's disease

21 January 2018

1 reference

Experimentally-derived functional form for a population-averaged high-temporal-resolution arterial input function for dynamic contrast-enhanced MRI.

21 January 2018

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Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data

21 January 2018

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The effect of isocapnic hyperoxia on neurophysiology as measured with MRI and MEG.

21 January 2018

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

21 January 2018

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Brain uptake of a fluorescent vector targeting the transferrin receptor: a novel application of in situ brain perfusion.

21 January 2018

1 reference

Diffusion of docosahexaenoic and eicosapentaenoic acids through the blood-brain barrier: An in situ cerebral perfusion study.

21 January 2018

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Lipid-mediated inflammation and degeneration of bioprosthetic heart valves

21 January 2018

1 reference

Mfsd2a is critical for the formation and function of the blood-brain barrier

21 January 2018

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Brain endothelial cell death: modes, signaling pathways, and relevance to neural development, homeostasis, and disease

21 January 2018

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Amyloid beta peptide-induced cerebral endothelial cell death involves mitochondrial dysfunction and caspase activation

21 January 2018

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Specific Role of Tight Junction Proteins Claudin-5, Occludin, and ZO-1 of the Blood–Brain Barrier in a Focal Cerebral Ischemic Insult

21 January 2018

1 reference

Deficiency in mural vascular cells coincides with blood-brain barrier disruption in Alzheimer's disease

21 January 2018

1 reference

Pericytes are required for blood-brain barrier integrity during embryogenesis

21 January 2018

1 reference

Vascular and epithelial junctions: a barrier for leucocyte migration

21 January 2018

1 reference

'Sealing off the CNS': cellular and molecular regulation of blood-brain barriergenesis

21 January 2018

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Learning causes synaptogenesis, whereas motor activity causes angiogenesis, in cerebellar cortex of adult rats

21 January 2018

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21 January 2018

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Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease

21 January 2018

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Amyloid Beta induces oxidative stress-mediated blood-brain barrier changes in capillary amyloid angiopathy.

21 January 2018

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R6/2 Huntington's disease mice develop early and progressive abnormal brain metabolism and seizures

21 January 2018

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Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cells

21 January 2018

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Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice

21 January 2018

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Ultrastructural localization of albumin transport across the cerebral microvasculature during experimental meningitis in the rat.

21 January 2018

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Blood-brain barrier dysfunction in Binswanger's disease; an immunohistochemical study

21 January 2018

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Blood-brain barrier tight junction disruption in human immunodeficiency virus-1 encephalitis

21 January 2018

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Cannabinoid receptor 2 signaling in peripheral immune cells modulates disease onset and severity in mouse models of Huntington's disease

21 January 2018

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Bone marrow transplantation confers modest benefits in mouse models of Huntington's disease

21 January 2018

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