Regulation of Immune Cell Functions by Metabolic Reprogramming. (Q54952659)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29651445%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

1 reference

8 February 2021

Regulation of Immune Cell Functions by Metabolic Reprogramming (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29651445%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

1 reference

12 October 2019

1 reference

18 October 2019

1 reference

8 February 2021

cell-mediated immunity

1 reference

PubMed publication ID

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29651445%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Jaehong Kim

1 reference

http://europepmc.org/abstract/PMC/5831954

13 June 2018

publication date

13 February 2018

5 references

3 April 2019

12 October 2019

18 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29651445%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

8 February 2021

Journal of Immunology Research

5 references

3 April 2019

12 October 2019

18 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29651445%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

8 February 2021

2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29651445%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

page(s)

8605471

1 reference

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Creative Commons Attribution 4.0 International

23 March 2020

4 references

3 April 2019

12 October 2019

18 October 2019

on focus list of Wikimedia project

8 February 2021

copyrighted

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ScienceSource

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Pyruvate Kinase M2 Activates mTORC1 by Phosphorylating AKT1S1

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The Macrophage Switch in Obesity Development

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Metabolic Enzymes Enjoying New Partnerships as RNA-Binding Proteins

14 June 2018

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Glycolysis controls the induction of human regulatory T cells by modulating the expression of FOXP3 exon 2 splicing variants

14 June 2018

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Metabolic Reprogramming of Immune Cells in Cancer Progression

14 June 2018

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Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.

14 June 2018

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Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

14 June 2018

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Transcription factors STAT6 and KLF4 implement macrophage polarization via the dual catalytic powers of MCPIP

14 June 2018

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PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation

14 June 2018

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SIRT1/PGC1α-Dependent Increase in Oxidative Phosphorylation Supports Chemotherapy Resistance of Colon Cancer

14 June 2018

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Tumors: wounds that do not heal-redux

14 June 2018

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Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages

14 June 2018

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S-glutathionylation reactions in mitochondrial function and disease

14 June 2018

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mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity.

14 June 2018

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Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

14 June 2018

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Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.

14 June 2018

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Macrophage activation and polarization: nomenclature and experimental guidelines

14 June 2018

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Memory CD8(+) T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development.

14 June 2018

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The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function

14 June 2018

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VDR status arbitrates the prometastatic effects of tumor-associated macrophages

14 June 2018

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PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation

14 June 2018

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Mechanisms driving macrophage diversity and specialization in distinct tumor microenvironments and parallelisms with other tissues

14 June 2018

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Metabolic requirements for the maintenance of self-renewing stem cells

14 June 2018

1 reference

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A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients

14 June 2018

1 reference

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Inhibition of tumor growth and alteration of associated macrophage cell type by an HO-1 inhibitor in breast carcinoma-bearing mice

14 June 2018

1 reference

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Very low density lipoprotein receptor (VLDLR) expression is a determinant factor in adipose tissue inflammation and adipocyte-macrophage interaction

14 June 2018

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Posttranscriptional control of T cell effector function by aerobic glycolysis

14 June 2018

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Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production

14 June 2018

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Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

14 June 2018

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Dichloroacetate improves immune dysfunction caused by tumor-secreted lactic acid and increases antitumor immunoreactivity

14 June 2018

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Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling.

14 June 2018

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Metabolism of inflammation limited by AMPK and pseudo-starvation

14 June 2018

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14 June 2018

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Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

14 June 2018

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Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

14 June 2018

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Macrophage plasticity and polarization: in vivo veritas

14 June 2018

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Differential macrophage programming in the tumor microenvironment

14 June 2018

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The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

14 June 2018

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Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

14 June 2018

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Trained immunity: a memory for innate host defense

14 June 2018

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B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

14 June 2018

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Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.

14 June 2018

1 reference

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Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation

14 June 2018

1 reference

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The REM phase of gene regulation

14 June 2018

1 reference

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Control of macrophage activation and function by PPARs

14 June 2018

1 reference

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Notch signaling determines the M1 versus M2 polarization of macrophages in antitumor immune responses

14 June 2018

1 reference

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Macrophage diversity enhances tumor progression and metastasis

14 June 2018

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THE METABOLISM OF TUMORS IN THE BODY

14 June 2018

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CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

14 June 2018

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mTOR regulates memory CD8 T-cell differentiation

14 June 2018

1 reference

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mTOR and HIF-1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome

14 June 2018

1 reference

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Enhancing CD8 T-cell memory by modulating fatty acid metabolism

14 June 2018

1 reference

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Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb

14 June 2018

1 reference

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Mitochondrial dysfunction and reactive oxygen species imbalance promote breast cancer cell motility through a CXCL14-mediated mechanism

14 June 2018

1 reference

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AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

14 June 2018

1 reference

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Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance

14 June 2018

1 reference

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Integration of metabolism and inflammation by lipid-activated nuclear receptors

14 June 2018

1 reference

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Cancer-related inflammation

14 June 2018

1 reference

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An antiinflammatory role for IKKbeta through the inhibition of "classical" macrophage activation

14 June 2018

1 reference

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Innate immunity, insulin resistance and type 2 diabetes.

14 June 2018

1 reference

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Regulation of HIF-1alpha stability through S-nitrosylation

14 June 2018

1 reference

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

14 June 2018

1 reference

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Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF.

14 June 2018

1 reference

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GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization

14 June 2018

1 reference

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Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation

14 June 2018

1 reference

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HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Multifaceted roles of glycolytic enzymes.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Novel roles of the autocrine motility factor/phosphoglucose isomerase in tumor malignancy

14 June 2018

1 reference

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The chemokine system in diverse forms of macrophage activation and polarization

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

14 June 2018

1 reference

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Obesity is associated with macrophage accumulation in adipose tissue

14 June 2018

1 reference

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HIF-1alpha is essential for myeloid cell-mediated inflammation

14 June 2018

1 reference

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Transcript-selective translational silencing by gamma interferon is directed by a novel structural element in the ceruloplasmin mRNA 3' untranslated region

14 June 2018

1 reference

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The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Specific phosphorylated forms of glyceraldehyde 3-phosphate dehydrogenase associate with human parainfluenza virus type 3 and inhibit viral transcription in vitro

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Lactate dehydrogenase and glyceraldehyde-phosphate dehydrogenase are single-stranded DNA-binding proteins that affect the DNA-polymerase-alpha-primase complex

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Macrophages in human breast disease: a quantitative immunohistochemical study

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Opposite Effects of M1 and M2 Macrophage Subtypes on Lung Cancer Progression.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Orphan Nuclear Receptor ERRα Controls Macrophage Metabolic Signaling and A20 Expression to Negatively Regulate TLR-Induced Inflammation.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

T lymphocyte regulation by mevalonate metabolism.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Molecular mechanisms that influence the macrophage m1-m2 polarization balance

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Cellular metabolism and macrophage functional polarization

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

HIF-1-mediated metabolic reprogramming reduces ROS levels and facilitates the metastatic colonization of cancers in lungs

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

The GAIT system: a gatekeeper of inflammatory gene expression.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Hexokinase II: the integration of energy metabolism and control of apoptosis

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Metabolic regulation of macrophages in tumor microenvironment

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Metabolic Characterization of Polarized M1 and M2 Bone Marrow-derived Macrophages Using Real-time Extracellular Flux Analysis

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Metabolic control of YAP and TAZ by the mevalonate pathway.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Impeding macrophage entry into hypoxic tumor areas by Sema3A/Nrp1 signaling blockade inhibits angiogenesis and restores antitumor immunity.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Glycolytic control of adjuvant-induced macrophage survival: role of PI3K, MEK1/2, and Bcl-2.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Autocrine motility factor signaling induces tumor apoptotic resistance by regulations Apaf‐1 and Caspase‐9 apoptosome expression

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Iron trafficking and metabolism in macrophages: contribution to the polarized phenotype

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831954

Substrate fate in activated macrophages: a comparison between innate, classic, and alternative activation

30 November 2018

1 reference

12 December 2020

Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes

1 reference

12 December 2020

Alternative splicing generates two lactate dehydrogenase subunits differentially expressed during hypoxia via HIF-1 in the shrimp Litopenaeus vannamei

1 reference

12 December 2020

Nutrient Competition: A New Axis of Tumor Immunosuppression

1 reference

12 December 2020

Identifiers

DOI

10.1155/2018/8605471

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29651445%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29651445%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

PubMed publication ID

29651445

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29651445%20AND%20SRC:MED&resulttype=core&format=json