Non-metabolic functions of glycolytic enzymes in tumorigenesis (Q38994977)

8 September 2017

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title

Non-metabolic functions of glycolytic enzymes in tumorigenesis (English)

1 reference

8 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27797379%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

X Yu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27797379%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

language of work or name

English

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publication date

31 October 2016

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8 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27797379%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27797379%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

issue

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27797379%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

2629-2636

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27797379%20AND%20SRC:MED&resulttype=core&format=json

Understanding the Warburg effect: the metabolic requirements of cell proliferation

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Nuclear pyruvate kinase M2 complex serves as a transcriptional coactivator of arylhydrocarbon receptor

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A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation

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Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase is regulated by acetylation

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Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms

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Nuclear lactate dehydrogenase modulates histone modification in human hepatocytes

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S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component

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Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf oncoprotein

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Methionine adenosyltransferase II-dependent histone H3K9 methylation at the COX-2 gene locus

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Cross-talk between histone H3 tails produces cooperative nucleosome acetylation.

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The Gcn5 bromodomain of the SAGA complex facilitates cooperative and cross-tail acetylation of nucleosomes

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A glycolytic burst drives glucose induction of global histone acetylation by picNuA4 and SAGA.

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Histone acetylation regulates intracellular pH.

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Glycolytic metabolism influences global chromatin structure

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Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes.

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SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases

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Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression.

21 January 2018

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Metabolic control of methylation and acetylation

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Yeast Tdh3 (glyceraldehyde 3-phosphate dehydrogenase) is a Sir2-interacting factor that regulates transcriptional silencing and rDNA recombination

21 January 2018

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Regulation of yeast pyruvate kinase by ultrasensitive allostery independent of phosphorylation

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Hypomethylation of hepatic nuclear DNA in rats fed with a carcinogenic methyl-deficient diet

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Reduced Histone Expression or a Defect in Chromatin Assembly Induces Respiration

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Histone hypoacetylation-activated genes are repressed by acetyl-CoA- and chromatin-mediated mechanism.

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SAICAR induces protein kinase activity of PKM2 that is necessary for sustained proliferative signaling of cancer cells

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Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase

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Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription

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Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1

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Aerobic glycolysis tunes YAP/TAZ transcriptional activity

21 January 2018

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Increased Expression of the Autocrine Motility Factor is Associated With Poor Prognosis in Patients With Clear Cell-Renal Cell Carcinoma.

21 January 2018

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The complex biology of autocrine motility factor/phosphoglucose isomerase (AMF/PGI) and its receptor, the gp78/AMFR E3 ubiquitin ligase

21 January 2018

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Phosphoglucose isomerase/autocrine motility factor promotes melanoma cell migration through ERK activation dependent on autocrine production of interleukin-8

21 January 2018

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Silencing of Autocrine Motility Factor Induces Mesenchymal-to-Epithelial Transition and Suppression of Osteosarcoma Pulmonary Metastasis

21 January 2018

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Autocrine motility factor modulates EGF-mediated invasion signaling

21 January 2018

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Autocrine motility factor promotes HER2 cleavage and signaling in breast cancer cells

21 January 2018

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Autocrine motility factor/phosphoglucose isomerase regulates ER stress and cell death through control of ER calcium release

21 January 2018

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Phosphoglycerate kinase-1 is a predictor of poor survival and a novel prognostic biomarker of chemoresistance to paclitaxel treatment in breast cancer

21 January 2018

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Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis

21 January 2018

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Pyruvate Kinase M2 Activates mTORC1 by Phosphorylating AKT1S1

21 January 2018

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Hepatitis C virus and its protein NS4B activate the cancer-related STAT3 pathway via the endoplasmic reticulum overload response

21 January 2018

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Protein kinase activity of rat brain hexokinase

21 January 2018

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Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb

21 January 2018

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Targeting cellular metabolism to improve cancer therapeutics

21 January 2018

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Balancing glycolytic flux: the role of 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatases in cancer metabolism

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Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

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The MCT4 Gene: A Novel, Potential Target for Therapy of Advanced Prostate Cancer.

21 January 2018

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Pyruvate and Metabolic Flexibility: Illuminating a Path Toward Selective Cancer Therapies

21 January 2018

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PKM2 regulates chromosome segregation and mitosis progression of tumor cells.

21 January 2018

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Lactate dehydrogenase and glyceraldehyde-phosphate dehydrogenase are single-stranded DNA-binding proteins that affect the DNA-polymerase-alpha-primase complex

21 January 2018

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Clotrimazole and bifonazole detach hexokinase from mitochondria of melanoma cells

21 January 2018

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Modulation of DNA polymerases alpha, delta and epsilon by lactate dehydrogenase and 3-phosphoglycerate kinase

31 March 2020

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Yeast carbon catabolite repression

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27797379

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Critical protein GAPDH and its regulatory mechanisms in cancer cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27797379