Trafficking in Alzheimer's Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin. (Q47592174)

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scientific article published on 27 October 2017

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English	Trafficking in Alzheimer's Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin.	scientific article published on 27 October 2017

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scholarly article

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Europe PubMed Central

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8 April 2020

Trafficking in Alzheimer's Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin (English)

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8 April 2020

Alzheimer's disease

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transmembrane transport

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transmembrane protein

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1

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8 April 2020

4

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8 April 2020

author name string

Carolin Thomas

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8 April 2020

Stefan Kins

3

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8 April 2020

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27 October 2017

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8 April 2020

Molecular Neurobiology

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8 April 2020

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8 April 2020

5809-5829

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8 April 2020

Alzheimer mechanisms and therapeutic strategies

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Adaptor protein interactions: modulators of amyloid precursor protein metabolism and Alzheimer's disease risk?

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

α-secretase in Alzheimer's disease: molecular identity, regulation and therapeutic potential

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Regulated intramembrane proteolysis--lessons from amyloid precursor protein processing

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Identification of a new presenilin-dependent zeta-cleavage site within the transmembrane domain of amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Amyloid beta-peptide is produced by cultured cells during normal metabolism

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Longer forms of amyloid beta protein: implications for the mechanism of intramembrane cleavage by gamma-secretase.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Presenilin: running with scissors in the membrane

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Molecular consequences of amyloid precursor protein and presenilin mutations causing autosomal-dominant Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Mean age of onset in familial Alzheimer's disease is determined by amyloid beta 42.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

gamma-Secretase: successive tripeptide and tetrapeptide release from the transmembrane domain of beta-carboxyl terminal fragment

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

A Greek Tragedy: The Growing Complexity of Alzheimer Amyloid Precursor Protein Proteolysis

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

η-Secretase processing of APP inhibits neuronal activity in the hippocampus

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

New tricks from an old dog: Another synaptotoxic fragment from APP

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Cleavage of amyloid-beta precursor protein (APP) by membrane-type matrix metalloproteinases

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Metalloproteinases in biology and pathology of the nervous system.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Shedding of membrane type matrix metalloproteinase 5 by a furin-type convertase: a potential mechanism for down-regulation

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Matrix metalloproteinase (MMP) system in brain: identification and characterization of brain-specific MMP highly expressed in cerebellum

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Generation of aggregation prone N-terminally truncated amyloid β peptides by meprin β depends on the sequence specificity at the cleavage site

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Metalloprotease meprin β is activated by transmembrane serine protease matriptase-2 at the cell surface thereby enhancing APP shedding

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Structural basis for the sheddase function of human meprin metalloproteinase at the plasma membrane

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The metalloprotease meprin β generates amino terminal-truncated amyloid β peptide species

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Metalloprotease meprin beta generates nontoxic N-terminal amyloid precursor protein fragments in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Presenilin 1 and Presenilin 2 Target γ-Secretase Complexes to Distinct Cellular Compartments

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Amyloid precursor protein and Notch intracellular domains are generated after transport of their precursors to the cell surface

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Causative and susceptibility genes for Alzheimer's disease: a review.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Trafficking and proteolytic processing of APP

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Beta-amyloid precursor protein localization in the Golgi apparatus in neurons and oligodendrocytes. An immunocytochemical structural and ultrastructural study in normal and axotomized neurons

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Amyloid precursor protein revisited: neuron-specific expression and highly stable nature of soluble derivatives.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Activity-induced convergence of APP and BACE-1 in acidic microdomains via an endocytosis-dependent pathway.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Sorting receptor SORLA--a trafficking path to avoid Alzheimer disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

An Endosomal‐Lysosomal Pathway for Degradation of Amyloid Precursor Protein a

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Flotillin-dependent clustering of the amyloid precursor protein regulates its endocytosis and amyloidogenic processing in neurons.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Axonal membrane proteins are transported in distinct carriers: a two-color video microscopy study in cultured hippocampal neurons

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neurons

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Native structure and physical properties of bovine brain kinesin and identification of the ATP-binding subunit polypeptide

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Conventional kinesin holoenzymes are composed of heavy and light chain homodimers

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Molecular genetics of kinesin light chains: generation of isoforms by alternative splicing

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

A specific light chain of kinesin associates with mitochondria in cultured cells

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Conventional kinesin: Biochemical heterogeneity and functional implications in health and disease.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Amyloid beta protein precursor (AbetaPP), but not AbetaPP-like protein 2, is bridged to the kinesin light chain by the scaffold protein JNK-interacting protein 1.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Quantitative analysis of APP axonal transport in neurons: role of JIP1 in enhanced APP anterograde transport

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Aβ production

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Axonal accumulation of synaptic markers in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Lipoprotein receptors – an evolutionarily ancient multifunctional receptor family

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The low-density lipoprotein receptor gene family: a cellular Swiss army knife?

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Functional Roles of the Interaction of APP and Lipoprotein Receptors.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

A receptor-mediated pathway for cholesterol homeostasis

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The role of lipoprotein receptors on the physiological function of APP.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Elements of neural adhesion molecules and a yeast vacuolar protein sorting receptor are present in a novel mammalian low density lipoprotein receptor family member

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The Vps10p-domain receptor family.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Building proteins with fibronectin type III modules

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Ligands bind to Sortilin in the tunnel of a ten-bladed beta-propeller domain

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Functional organization of the sortilin Vps10p domain

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Calsyntenin-1, a proteolytically processed postsynaptic membrane protein with a cytoplasmic calcium-binding domain

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Evolution and diversity of cadherins and catenins

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The calsyntenins--a family of postsynaptic membrane proteins with distinct neuronal expression patterns

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The specific α-neurexin interactor calsyntenin-3 promotes excitatory and inhibitory synapse development

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Calsyntenin-1 docks vesicular cargo to kinesin-1

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The low-density-lipoprotein receptor-related protein (LRP) is processed by furin in vivo and in vitro.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

LRP1 modulates APP trafficking along early compartments of the secretory pathway

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Functional role of lipoprotein receptors in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Alpha-2 macroglobulin is genetically associated with Alzheimer disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP). Evidence that LRP contributes to the pathogenesis of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

APP gene family. Alternative splicing generates functionally related isoforms

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Phosphorylation of LRP1 regulates the interaction with Fe65

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Rapid endocytosis of the low density lipoprotein receptor-related protein modulates cell surface distribution and processing of the beta-amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The cytoplasmic domain of the LDL receptor-related protein regulates multiple steps in APP processing

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

LRP1 Modulates APP Intraneuronal Transport and Processing in Its Monomeric and Dimeric State

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The low density lipoprotein receptor-related protein 1B retains beta-amyloid precursor protein at the cell surface and reduces amyloid-beta peptide production

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

LRP1b shows restricted expression in human tissues and binds to several extracellular ligands, including fibrinogen and apoE – carrying lipoproteins

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Evidence that the newly cloned low-density-lipoprotein receptor related protein (LRP) is the alpha 2-macroglobulin receptor

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The putative tumor suppressor LRP1B, a novel member of the low density lipoprotein (LDL) receptor family, exhibits both overlapping and distinct properties with the LDL receptor-related protein

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The low density lipoprotein receptor-related protein (LRP) is a novel beta-secretase (BACE1) substrate.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The role of low-density receptor-related protein 1 (LRP1) as a competitive substrate of the amyloid precursor protein (APP) for BACE1

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Low density lipoprotein receptor-related protein (LRP) interacts with presenilin 1 and is a competitive substrate of the amyloid precursor protein (APP) for gamma-secretase

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

LRP1 mediates bidirectional transcytosis of amyloid-β across the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Clearance of amyloid-beta by circulating lipoprotein receptors

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

LR11, a mosaic LDL receptor family member, mediates the uptake of ApoE-rich lipoproteins in vitro

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

SorLA regulates the activity of lipoprotein lipase by intracellular trafficking

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The mosaic receptor sorLA/LR11 binds components of the plasminogen-activating system and platelet-derived growth factor-BB similarly to LRP1 (low-density lipoprotein receptor-related protein), but mediates slow internalization of bound ligand.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Activation and functional characterization of the mosaic receptor SorLA/LR11.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Cytokine-Like Factor 1, an Essential Facilitator of Cardiotrophin-Like Cytokine:Ciliary Neurotrophic Factor Receptor α Signaling and sorLA-Mediated Turnover.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

SorLA and CLC:CLF-1-dependent Downregulation of CNTFRα as Demonstrated by Western Blotting, Inhibition of Lysosomal Enzymes, and Immunocytochemistry

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Molecular dissection of the interaction between amyloid precursor protein and its neuronal trafficking receptor SorLA/LR11.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

SorLA complement-type repeat domains protect the amyloid precursor protein against processing

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Unique expression pattern of a novel mosaic receptor in the developing cerebral cortex

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Risk factor SORL1: from genetic association to functional validation in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Loss of apolipoprotein E receptor LR11 in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

SORLA-dependent and -independent functions for PACS1 in control of amyloidogenic processes

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Sortilin and SorLA display distinct roles in processing and trafficking of amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Polarized trafficking of the sorting receptor SorLA in neurons and MDCK cells.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Tumour necrosis factor alpha-converting enzyme mediates ectodomain shedding of Vps10p-domain receptor family members

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

SorLA signaling by regulated intramembrane proteolysis

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Distinct Functions for Anterograde and Retrograde Sorting of SORLA in Amyloidogenic Processes in the Brain.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Sorting nexins provide diversity for retromer-dependent trafficking events

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

VPS35 haploinsufficiency increases Alzheimer's disease neuropathology.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Genomic convergence to identify candidate genes for Alzheimer disease on chromosome 10.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

SORCS1 and APOE polymorphisms interact to confer risk for late-onset Alzheimer's disease in a Northern Han Chinese population

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The genetic variation of SORCS1 is associated with late-onset Alzheimer's disease in Chinese Han population.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Identification and characterization of SorCS, a third member of a novel receptor family

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The Sorting Receptor SorCS1 Regulates Trafficking of Neurexin and AMPA Receptors.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Control of neuronal synapse specification by a highly dedicated alternative splicing program.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Diabetes-associated SorCS1 regulates Alzheimer's amyloid-beta metabolism: evidence for involvement of SorL1 and the retromer complex

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

SorCS1 variants and amyloid precursor protein (APP) are co-transported in neurons but only SorCS1c modulates anterograde APP transport.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Transient expression of SorCS in developing telencephalic and mesencephalic structures of the mouse.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Spatiotemporal expression analysis of the growth factor receptor SorCS3.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Impact of genetic variation in SORCS1 on memory retention

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Characterization of sorCS1, an alternatively spliced receptor with completely different cytoplasmic domains that mediate different trafficking in cells

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Different motifs regulate trafficking of SorCS1 isoforms

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Do GGA adaptors bind internal DXXLL motifs?

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Positional cloning of Sorcs1, a type 2 diabetes quantitative trait locus

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

SORCS1: a novel human type 2 diabetes susceptibility gene suggested by the mouse

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

High-resolution quantitative trait locus analysis reveals multiple diabetes susceptibility loci mapped to intervals<800 kb in the species-conserved Niddm1i of the GK rat.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Distribution of NTS3 receptor/sortilin mRNA and protein in the rat central nervous system

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Expression of the 100-kDa neurotensin receptor sortilin during mouse embryonal development

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

SorCS3 does not require propeptide cleavage to bind nerve growth factor.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Human sorCS1 binds sortilin and hampers its cellular functions.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Sortilin is essential for proNGF-induced neuronal cell death

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Sortilin facilitates signaling of ciliary neurotrophic factor and related helical type 1 cytokines targeting the gp130/leukemia inhibitory factor receptor beta heterodimer

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Sortilin/neurotensin receptor-3 binds and mediates degradation of lipoprotein lipase

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Endocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor families

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

SNX1 defines an early endosomal recycling exit for sortilin and mannose 6-phosphate receptors

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Sortilin mediates the lysosomal targeting of cathepsins D and H

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The intracellular domain of sortilin interacts with amyloid precursor protein and regulates its lysosomal and lipid raft trafficking

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Homo- and heterodimerization of APP family members promotes intercellular adhesion

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP)

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Preservation of cortical sortilin protein levels in MCI and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Sortilin Fragments Deposit at Senile Plaques in Human Cerebrum

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

BACE1 retrograde trafficking is uniquely regulated by the cytoplasmic domain of sortilin

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Amyloid beta₁₋₄₂ (Aβ₄₂) up-regulates the expression of sortilin via the p75(NTR)/RhoA signaling pathway

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Sortilin, SorCS1b, and SorLA Vps10p sorting receptors, are novel gamma-secretase substrates

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Neuronal brain-derived neurotrophic factor is synthesized in excess, with levels regulated by sortilin-mediated trafficking and lysosomal degradation.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Shedding of the luminal domain of the neurotensin receptor-3/sortilin in the HT29 cell line

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Genetic Risk Score and Risk of Myocardial Infarction in Hispanics

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

A genome-wide association study of a coronary artery disease risk variant

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Cardiovascular disease and Alzheimer's disease: common links

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

A Genetic Variant of the Sortilin 1 Gene is Associated with Reduced Risk of Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

No association of SORT1 gene polymorphism with sporadic Alzheimer's disease in the Chinese Han population

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Potential mechanisms of progranulin-deficient FTLD

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Epidemiology and genetics of frontotemporal dementia/Pick's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

C-terminus of progranulin interacts with the beta-propeller region of sortilin to regulate progranulin trafficking

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Misregulation of human sortilin splicing leads to the generation of a nonfunctional progranulin receptor

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The X11/Mint family of adaptor proteins.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Alcadein cleavages by amyloid beta-precursor protein (APP) alpha- and gamma-secretases generate small peptides, p3-Alcs, indicating Alzheimer disease-related gamma-secretase dysfunction.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Constitutive cleavage of the single-pass transmembrane protein alcadeinα prevents aberrant peripheral retention of Kinesin-1.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and Alzheimer's disease: evidence for γ-secretase dysfunction

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ production

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Proteomic changes in cerebrospinal fluid of presymptomatic and affected persons carrying familial Alzheimer disease mutations

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Calsyntenin-3 C-terminal fragment accumulates in dystrophic neurites surrounding aβ plaques in tg2576 mouse and Alzheimer disease brains: its neurotoxic role in mediating dystrophic neurite formation

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Calsyntenins mediate TGN exit of APP in a kinesin-1-dependent manner.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Phosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Molecular characterization of a trafficking organelle: dissecting the axonal paths of calsyntenin-1 transport vesicles

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Inhibition of APP trafficking by tau protein does not increase the generation of amyloid-beta peptides

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Axonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cells

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Rab5-stimulated up-regulation of the endocytic pathway increases intracellular beta-cleaved amyloid precursor protein carboxyl-terminal fragment levels and Abeta production

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Alzheimer amyloid protein precursor is localized in nerve terminal preparations to Rab5-containing vesicular organelles distinct from those implicated in the synaptic vesicle pathway

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Synaptic organizing complexes

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

APLP1 Is a Synaptic Cell Adhesion Molecule, Supporting Maintenance of Dendritic Spines and Basal Synaptic Transmission.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Shedding of APP limits its synaptogenic activity and cell adhesion properties.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Amyloid precursor protein dimerization and synaptogenic function depend on copper binding to the growth factor-like domain

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Neuroligins and neurexins: linking cell adhesion, synapse formation and cognitive function

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Cell adhesion molecules: signalling functions at the synapse

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Calsyntenin-3 molecular architecture and interaction with neurexin 1α.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Microglial malfunction: the third rail in the development of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Do Microglia Default on Network Maintenance in Alzheimer's Disease?

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted β-amyloid precursor protein and mediates its degradation

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0806-X

21 January 2018

Distinct intramembrane cleavage of the beta-amyloid precursor protein family resembling gamma-secretase-like cleavage of Notch

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CELSR2-PSRC1-SORT1 gene expression and association with coronary artery disease and plasma lipid levels in an Asian Indian cohort

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of amyloidogenic C-terminal fragments during rapid axonal transport in vivo of beta-amyloid precursor protein in the optic nerve

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The YXXL motif, but not the two NPXY motifs, serves as the dominant endocytosis signal for low density lipoprotein receptor-related protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integration of endocytosis and signal transduction by lipoprotein receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid precursor protein is synthesized by retinal ganglion cells, rapidly transported to the optic nerve plasma membrane and nerve terminals, and metabolized.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E and Alzheimer's disease. A rapidly expanding field with medical and epidemiological consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An isoform of kinesin light chain specific for the Golgi complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer beta/A4 amyloid precursor protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel conserved sorting motif required for retromer-mediated endosome-to-TGN retrieval

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that production and release of amyloid beta-protein involves the endocytic pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of the proximal NPXY motif impairs early steps in LRP1 biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease-related alterations in synaptic density: neocortex and hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraneuronal compartments of the amyloid precursor protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression profile of activated microglia under conditions associated with dopamine neuronal damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive shedding of the amyloid precursor protein ectodomain is up-regulated by tumour necrosis factor-alpha converting enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of sorting signals in the beta-amyloid precursor protein cytoplasmic domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-amyloid precursor protein can be transported independent of any sorting signal to the axonal and dendritic compartment

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advances in understanding the molecular basis of frontotemporal dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural basis for amyloidogenic peptide recognition by sorLA

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The three sorCS genes are differentially expressed and regulated by synaptic activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Β-site APP-cleaving enzyme 1 trafficking and Alzheimer's disease pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal sorting and processing of amyloid precursor protein: implications for Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trafficking of cell-surface amyloid beta-protein precursor. I. Secretion, endocytosis and recycling as detected by labeled monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TARDBP mutation analysis in TDP-43 proteinopathies and deciphering the toxicity of mutant TDP-43

1 reference

https://pubmed.ncbi.nlm.nih.gov/29079999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12035-017-0806-X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29079999%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29079999%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

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