Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex (Q24303383)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20230749%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex (English)

1 reference

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19 January 2020

1 reference

1 reference

GOA release 2020-03-11

Golgi to endosome transport

1 reference

GOA release 2020-03-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20230749%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Patricia V Burgos

1 reference

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19 January 2020

Gonzalo A Mardones

1 reference

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19 January 2020

Luis L P daSilva

1 reference

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19 January 2020

Yogikala Prabhu

1 reference

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19 January 2020

James H Hurley

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20230749%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Juan S Bonifacino

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20230749%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

language of work or name

English

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publication date

1 March 2010

1 reference

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19 January 2020

number of pages

1 reference

inferred from page(s)

published in

Developmental Cell

1 reference

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19 January 2020

volume

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19 January 2020

issue

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19 January 2020

page(s)

425-436

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A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein

19 January 2020

cites work

1 reference

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ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures

19 March 2017

1 reference

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Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 gamma-sigma1 and AP-3 delta-sigma3 hemicomplexes

19 March 2017

1 reference

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Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Functional and physical interactions of the adaptor protein complex AP-4 with ADP-ribosylation factors (ARFs).

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

19 March 2017

1 reference

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Characterization of a fourth adaptor-related protein complex

19 March 2017

1 reference

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AP-4, a novel protein complex related to clathrin adaptors

19 March 2017

1 reference

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Specificity of interaction between adaptor-complex medium chains and the tyrosine-based sorting motifs of TGN38 and lgp120

19 March 2017

1 reference

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A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex

19 March 2017

1 reference

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Molecular architecture and functional model of the endocytic AP2 complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

A structural explanation for the recognition of tyrosine-based endocytotic signals

19 March 2017

1 reference

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Inference of macromolecular assemblies from crystalline state

19 March 2017

1 reference

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Functional gamma-secretase complex assembly in Golgi/trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and gamma-secretase substrates

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

AP-4 binds basolateral signals and participates in basolateral sorting in epithelial MDCK cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Signal-binding specificity of the mu4 subunit of the adaptor protein complex AP-4

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Evidence that production and release of amyloid beta-protein involves the endocytic pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Interaction of tyrosine-based sorting signals with clathrin-associated proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

The trans-Golgi network accessory protein p56 promotes long-range movement of GGA/clathrin-containing transport carriers and lysosomal enzyme sorting.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Signals for sorting of transmembrane proteins to endosomes and lysosomes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Overcoming expression and purification problems of RhoGDI using a family of "parallel" expression vectors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

AP-3-dependent trafficking and disease: the first decade

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Accumulation of AMPA receptors in autophagosomes in neuronal axons lacking adaptor protein AP-4.

27 September 2017

1 reference

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The gamma/sigma1 and alpha/sigma2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor.

27 September 2017

1 reference

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The functions of mammalian amyloid precursor protein and related amyloid precursor-like proteins

27 September 2017

1 reference

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Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis

27 September 2017

1 reference

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Amyloid precursor protein and Notch intracellular domains are generated after transport of their precursors to the cell surface

27 September 2017

1 reference

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Role of the endocytic machinery in the sorting of lysosome-associated membrane proteins

27 September 2017

1 reference

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RNA interference-mediated silencing of X11alpha and X11beta attenuates amyloid beta-protein levels via differential effects on beta-amyloid precursor protein processing.

27 September 2017

1 reference

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Presenilin complexes with the C-terminal fragments of amyloid precursor protein at the sites of amyloid beta-protein generation

27 September 2017

1 reference

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A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor

27 September 2017

1 reference

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The medium subunits of adaptor complexes recognize distinct but overlapping sets of tyrosine-based sorting signals

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Cleavage of rabaptin-5 blocks endosome fusion during apoptosis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Localization of TGN38 to the trans-Golgi network: involvement of a cytoplasmic tyrosine-containing sequence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer beta/A4 amyloid precursor protein.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Chloroquine inhibits intracellular degradation but not secretion of Alzheimer beta/A4 amyloid precursor protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Adaptor protein complex-4 (AP-4) is expressed in the central nervous system neurons and interacts with glutamate receptor delta2.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Phosphorylation of threonine 156 of the mu2 subunit of the AP2 complex is essential for endocytosis in vitro and in vivo

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841041

Enhanced release of amyloid beta-protein from codon 670/671 "Swedish" mutant beta-amyloid precursor protein occurs in both secretory and endocytic pathways

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20230749

12 December 2020

inferred from PubMed ID database lookup

Structural determinants of interaction of tyrosine-based sorting signals with the adaptor medium chains

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20230749

12 December 2020

inferred from PubMed ID database lookup

Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20230749

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.DEVCEL.2010.01.015

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20230749%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20230749%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

20230749

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20230749%20AND%20SRC:MED&resulttype=core&format=json