Expression of human cationic trypsinogen (PRSS1) in murine acinar cells promotes pancreatitis and apoptotic cell death (Q33654180)

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13 March 2020

title

Expression of human cationic trypsinogen (PRSS1) in murine acinar cells promotes pancreatitis and apoptotic cell death (English)

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13 March 2020

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13 March 2020

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13 March 2020

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13 March 2020

T Athwal

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13 March 2020

W Huang

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13 March 2020

R Mukherjee

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13 March 2020

D Latawiec

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13 March 2020

R Clarke

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K Smith

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F Campbell

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C Merriman

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13 March 2020

D Criddle

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13 March 2020

R Sutton

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publication date

10 April 2014

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13 March 2020

published in

Cell Death and Disease

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volume

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page(s)

e1165

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Cerulein-induced chronic pancreatitis does not require intra-acinar activation of trypsinogen in mice

13 March 2020

cites work

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Intra-acinar trypsinogen activation mediates early stages of pancreatic injury but not inflammation in mice with acute pancreatitis

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Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis

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Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo

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Suppression of transforming growth factor beta signalling aborts caerulein induced pancreatitis and eliminates restricted stimulation at high caerulein concentrations

21 June 2018

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Characterisation of a transgenic mouse expressing R122H human cationic trypsinogen

21 June 2018

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Calcium-dependent release of NO from intracellular S-nitrosothiols

21 June 2018

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Transgenic expression of pancreatic secretory trypsin inhibitor-I ameliorates secretagogue-induced pancreatitis in mice

21 June 2018

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Regulation of p53 and MDM2 activity by MTBP.

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Clinical and genetic characteristics of hereditary pancreatitis in Europe

21 June 2018

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An mSin3A interaction domain links the transcriptional activity of KLF11 with its role in growth regulation

21 June 2018

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The N34S mutation of SPINK1 (PSTI) is associated with a familial pattern of idiopathic chronic pancreatitis but does not cause the disease

21 June 2018

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Molecular pathology and evolutionary and physiological implications of pancreatitis-associated cationic trypsinogen mutations

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 January 2018

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21 January 2018

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Menadione-induced reactive oxygen species generation via redox cycling promotes apoptosis of murine pancreatic acinar cells.

21 January 2018

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21 January 2018

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Digesting new information about the role of trypsin in pancreatitis

21 January 2018

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21 January 2018

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12 December 2020

Early events in acute pancreatitis

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12 December 2020

Hereditary pancreatitis in North America: the Pittsburgh-Midwest Multi-Center Pancreatic Study Group Study

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12 December 2020

Induction of apoptosis in pancreatic acinar cells reduces the severity of acute pancreatitis

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12 December 2020

Search for the trigger mechanism of pancreatitis

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12 December 2020

Cytokines and acute pancreatitis

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12 December 2020

Comparative studies on the mechanism of activation of the two human trypsinogens

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12 December 2020

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12 December 2020

Reactive oxygen species induced by bile acid induce apoptosis and protect against necrosis in pancreatic acinar cells

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Identifiers

DOI

10.1038/CDDIS.2014.120

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722290%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722290%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

PubMed publication ID

24722290

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722290%20AND%20SRC:MED&resulttype=core&format=json