Intracellular trypsin induces pancreatic acinar cell death but not NF-kappaB activation (Q37285222)

19 August 2017

Intracellular trypsin induces pancreatic acinar cell death but not NF-kappaB activation (English)

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19 August 2017

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1 reference

Baoan Ji

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19 August 2017

Sebastian Gaiser

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19 August 2017

Xueqing Chen

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19 August 2017

Stephen A Ernst

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19 August 2017

Craig D Logsdon

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19 August 2017

language of work or name

English

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publication date

20 April 2009

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Journal of Biological Chemistry

19 August 2017

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inferred from page(s)

published in

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19 August 2017

284

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19 August 2017

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19 August 2017

17488-17498

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

19 August 2017

1 reference

Furin at the cutting edge: from protein traffic to embryogenesis and disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Cholecystokinin induces caspase activation and mitochondrial dysfunction in pancreatic acinar cells. Roles in cell injury processes of pancreatitis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

The IKK/NF-kappa B pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

CCK independently activates intracellular trypsinogen and NF-kappaB in rat pancreatic acinar cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Relationship between NF-kappaB and trypsinogen activation in rat pancreas after supramaximal caerulein stimulation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

The role of cysteine proteases in intracellular pancreatic serine protease activation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Trypsin activates pancreatic duct epithelial cell ion channels through proteinase-activated receptor-2.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Cloning and characterization of human protease-activated receptor 4

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

A simplified system for generating recombinant adenoviruses

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Gabexate for the prevention of pancreatic damage related to endoscopic retrograde cholangiopancreatography. Gabexate in digestive endoscopy--Italian Group

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Intracellular vacuoles in experimental acute pancreatitis in rats and mice are an acidified compartment

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Pathogenesis of acute pancreatitis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Secretagogues differentially activate endoplasmic reticulum stress responses in pancreatic acinar cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Intracellular activation of digestive zymogens in rat pancreatic acini. Stimulation by high doses of cholecystokinin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Experimental models of acute pancreatitis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Evidence of Intracellular Activation of Serine Proteases in Acute Cerulein-Induced Pancreatitis in Rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Proteinase-activated receptor-2 (PAR-2): regulation of salivary and pancreatic exocrine secretion in vivo in rats and mice

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Species differences between rat and mouse CCKA receptors determine the divergent acinar cell response to the cholecystokinin analog JMV-180.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Processing of mutated proinsulin with tetrabasic cleavage sites to mature insulin reflects the expression of furin in nonendocrine cell lines

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Free proteolytic enzymes in pancreatic juice of patients with acute pancreatitis

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Structural and functional integrity of specificity and catalytic sites of trypsin.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Cell death in pancreatitis: caspases protect from necrotizing pancreatitis

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitis

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Human pancreatic acinar cells lack functional responses to cholecystokinin and gastrin

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Early NF-kappaB activation is associated with hormone-induced pancreatitis.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719389

Cerulein-induced in vitro activation of trypsinogen in rat pancreatic acini is mediated by cathepsin B

3 September 2018

1 reference

12 December 2020

NF-kappaB activation in pancreas induces pancreatic and systemic inflammatory response

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12 December 2020

The role of lysosomal proteases in the pathogenesis of pancreatitis

1 reference

12 December 2020

Effects of ethionine on digestive enzyme synthesis and discharge by mouse pancreas

1 reference

12 December 2020

Pancreatic effects of ethionine: blockade of exocytosis and appearance of crinophagy and autophagy precede cellular necrosis

1 reference

12 December 2020

Highly sensitive peptide-4-methylcoumaryl-7-amide substrates for blood-clotting proteases and trypsin

1 reference

12 December 2020

Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis

1 reference

12 December 2020

Chemokine gene expression in rat pancreatic acinar cells is an early event associated with acute pancreatitis

1 reference

12 December 2020

Zymogen proteolysis within the pancreatic acinar cell is associated with cellular injury

1 reference

12 December 2020

NF-kappaB/Rel activation in cerulein pancreatitis

1 reference

12 December 2020

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.005520

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19 August 2017

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19 August 2017

PubMed publication ID

19383608

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