Digesting new information about the role of trypsin in pancreatitis (Q43146280)

14 November 2017

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Digesting new information about the role of trypsin in pancreatitis (English)

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14 November 2017

Baoan Ji

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14 November 2017

Craig D Logsdon

series ordinal

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14 November 2017

language of work or name

English

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publication date

25 October 2011

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14 November 2017

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14 November 2017

141

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14 November 2017

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14 November 2017

1972-1975

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Intra-acinar trypsinogen activation mediates early stages of pancreatic injury but not inflammation in mice with acute pancreatitis

14 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327863

Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327863

Intracellular autoactivation of human cationic trypsinogen mutants causes reduced trypsinogen secretion and acinar cell death

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327863

Ras activity levels control the development of pancreatic diseases.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327863

Intracellular trypsin induces pancreatic acinar cell death but not NF-kappaB activation

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327863

New insights into the mechanisms of pancreatitis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327863

Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: a novel disease mechanism

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327863

Transgenic expression of pancreatic secretory trypsin inhibitor-I ameliorates secretagogue-induced pancreatitis in mice

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327863

CCK independently activates intracellular trypsinogen and NF-kappaB in rat pancreatic acinar cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327863

Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327863

Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327863

Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327863

Free proteolytic enzymes in pancreatic juice of patients with acute pancreatitis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327863

Pancreatic gene expression during the initiation of acute pancreatitis: identification of EGR-1 as a key regulator

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327863

Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327863

Trypsin activity is not involved in premature, intrapancreatic trypsinogen activation

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327863

Protease inhibitors in acute pancreatitis: lessons from the bench and failed clinical trials

15 August 2018

1 reference

12 December 2020

NF-kappaB activation in pancreas induces pancreatic and systemic inflammatory response

1 reference

12 December 2020

Search for the trigger mechanism of pancreatitis

1 reference

12 December 2020

Cholecystokinin induction of mob-1 chemokine expression in pancreatic acinar cells requires NF-kappaB activation

1 reference

12 December 2020

10.1053/J.GASTRO.2011.10.021

Identifiers

DOI

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release_jir4ear5tbakzogub6gj22ehta

14 November 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/jir4ear5tbakzogub6gj22ehta

24 November 2022

mapped directly with Wikidata item

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14 November 2017

PubMed publication ID

22033179

1 reference