Trypanothione-dependent synthesis of deoxyribonucleotides by Trypanosoma brucei ribonucleotide reductase (Q31813150)

4 July 2017

title

Trypanothione-dependent synthesis of deoxyribonucleotides by Trypanosoma brucei ribonucleotide reductase (English)

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4 July 2017

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Dormeyer M

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4 July 2017

Reckenfelderbäumer N

series ordinal

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4 July 2017

Ludemann H

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Krauth-Siegel RL

series ordinal

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4 July 2017

language of work or name

English

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publication date

9 January 2001

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Journal of Biological Chemistry

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published in

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volume

276

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4 July 2017

page(s)

10602-10606

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Ribonucleotide reductases

4 July 2017

cites work

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Cloning, sequencing and expression of ribonucleotide reductase R2 from Trypanosoma brucei

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Allosteric regulation of Trypanosoma brucei ribonucleotide reductase studied in vitro and in vivo

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Ribonucleotide reductase is regulated via the R2 subunit during the life cycle of Trypanosoma brucei.

21 January 2018

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Metabolism and functions of trypanothione in the Kinetoplastida

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Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress

21 January 2018

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Enzymes of parasite thiol metabolism as drug targets

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Trypanothione-dependent peroxide metabolism in Trypanosoma cruzi different stages.

21 January 2018

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A Unique Cascade of Oxidoreductases Catalyses Trypanothione-Mediated Peroxide Metabolism in Crithidia fasciculata

21 January 2018

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Glutathione and trypanothione in parasitic hydroperoxide metabolism

21 January 2018

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Trypanosoma brucei tryparedoxin, a thioredoxin-like protein in African trypanosomes.

21 January 2018

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Cloning, sequencing, overproduction and purification of trypanothione reductase from Trypanosoma cruzi

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Ribonucleotide reductase from calf thymus. Purification and properties

21 January 2018

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Ribonucleotide reductase of Brevibacterium ammoniagenes is a manganese enzyme.

21 January 2018

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Tissue sulfhydryl groups

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Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding

21 January 2018

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Reduction of Ribonucleotides

21 January 2018

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Two additional glutaredoxins exist in Escherichia coli: glutaredoxin 3 is a hydrogen donor for ribonucleotide reductase in a thioredoxin/glutaredoxin 1 double mutant.

21 January 2018

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Cloning, expression, and characterization of a novel Escherichia coli thioredoxin

21 January 2018

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Activation of active-site cysteine residues in the peroxiredoxin-type tryparedoxin peroxidase of Crithidia fasciculata

21 January 2018

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Sequence, heterologous expression and functional characterization of a novel tryparedoxin from Crithidia fasciculata

21 January 2018

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Identification and functional characterization of thioredoxin from Trypanosoma brucei brucei.

21 January 2018

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Crystallization and preliminary crystallographic analysis of trypanothione reductase from Trypanosoma cruzi , the causative agent of Chagas' disease

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M010352200

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4 July 2017

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