The monocarboxylate transporter 4 is required for glycolytic reprogramming and inflammatory response in macrophages. (Q34801576)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25406319%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

The monocarboxylate transporter 4 is required for glycolytic reprogramming and inflammatory response in macrophages (English)

1 reference

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23 February 2020

1 reference

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23 February 2020

Zheng Tan

1 reference

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23 February 2020

Na Xie

1 reference

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23 February 2020

Sami Banerjee

1 reference

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23 February 2020

Huachun Cui

1 reference

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23 February 2020

Mingui Fu

1 reference

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23 February 2020

Victor J Thannickal

1 reference

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23 February 2020

language of work or name

English

0 references

publication date

18 November 2014

1 reference

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Journal of Biological Chemistry

23 February 2020

published in

1 reference

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23 February 2020

volume

290

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23 February 2020

issue

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23 February 2020

page(s)

46-55

1 reference

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Lactate storm marks cerebral metabolism following brain trauma

23 February 2020

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8 July 2018

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8 July 2018

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The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism

8 July 2018

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8 July 2018

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The monocarboxylate transporter family--role and regulation

8 July 2018

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Lactate: a metabolic key player in cancer

8 July 2018

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CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors

8 July 2018

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Otto Warburg's contributions to current concepts of cancer metabolism

8 July 2018

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8 July 2018

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Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha

8 July 2018

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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

8 July 2018

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8 July 2018

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Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation

8 July 2018

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8 July 2018

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8 July 2018

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Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Lactate boosts TLR4 signaling and NF-kappaB pathway-mediated gene transcription in macrophages via monocarboxylate transporters and MD-2 up-regulation

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism.

8 July 2018

1 reference

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Negative regulation of toll-like receptor-mediated immune responses

8 July 2018

1 reference

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Why do cancers have high aerobic glycolysis?

8 July 2018

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TLR2 is mobilized into an apical lipid raft receptor complex to signal infection in airway epithelial cells

8 July 2018

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Pseudomonas aeruginosa Flagella Activate Airway Epithelial Cells through asialoGM1 and Toll-Like Receptor 2 as well as Toll-Like Receptor 5

8 July 2018

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Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2

8 July 2018

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The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells

8 July 2018

1 reference

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Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis.

21 January 2018

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Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch

21 January 2018

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Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis

21 January 2018

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Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/25406319

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibitory effect of tumor cell-derived lactic acid on human T cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25406319

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M114.603589

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25406319%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25406319%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

PubMed publication ID

25406319

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25406319%20AND%20SRC:MED&resulttype=core&format=json