Mesenchymal stem cell transformation and sarcoma genesis (Q34654560)

3 August 2017

title

Mesenchymal stem cell transformation and sarcoma genesis (English)

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3 August 2017

main subject

mesenchymal stem cell

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inferred from title

author

Anne-Marie Cleton-Jansen

object named as

Anne-Marie Cleton-Jansen

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Pancras C.W. Hogendoorn

object named as

Pancras C W Hogendoorn

1 reference

3 August 2017

Wei Xiao

1 reference

3 August 2017

Alexander B Mohseny

1 reference

3 August 2017

Anne-Marie Cleton-Jansen

1 reference

3 August 2017

publication date

23 July 2013

1 reference

Clinical Sarcoma Research

3 August 2017

published in

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3 August 2017

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3 August 2017

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3 August 2017

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Modeling clear cell sarcomagenesis in the mouse: cell of origin differentiation state impacts tumor characteristics

3 August 2017

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Secondary peripheral chondrosarcoma evolving from osteochondroma as a result of outgrowth of cells with functional EXT

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FUS-CHOP fusion protein expression coupled to p53 deficiency induces liposarcoma in mouse but not in human adipose-derived mesenchymal stem/stromal cells.

7 July 2018

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IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours

7 July 2018

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7 July 2018

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The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in.

7 July 2018

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Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

7 July 2018

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Bone marrow mesenchymal stem cells: historical overview and concepts

7 July 2018

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7 July 2018

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Therapeutic potential of adult bone marrow-derived mesenchymal stem cells in diseases of the skeleton

7 July 2018

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Osteosarcoma originates from mesenchymal stem cells in consequence of aneuploidization and genomic loss of Cdkn2.

7 July 2018

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Targeted mutation of p53 and Rb in mesenchymal cells of the limb bud produces sarcomas in mice

7 July 2018

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Targeting PI3K signalling in cancer: opportunities, challenges and limitations

7 July 2018

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Genetically transforming human mesenchymal stem cells to sarcomas: changes in cellular phenotype and multilineage differentiation potential

7 July 2018

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The NFATc2 gene is involved in a novel cloned translocation in a Ewing sarcoma variant that couples its function in immunology to oncology

7 July 2018

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Loss of p53 induces tumorigenesis in p21-deficient mesenchymal stem cells

7 July 2018

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Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient

7 July 2018

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Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program

7 July 2018

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EWS-FLI1 induces developmental abnormalities and accelerates sarcoma formation in a transgenic mouse model

7 July 2018

1 reference

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A chondrogenic gene expression signature in mesenchymal stem cells is a classifier of conventional central chondrosarcoma.

7 July 2018

1 reference

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Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage

7 July 2018

1 reference

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FUS-DDIT3 prevents the development of adipocytic precursors in liposarcoma by repressing PPARgamma and C/EBPalpha and activating eIF4E.

7 July 2018

1 reference

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Osteosarcoma development and stem cell differentiation

7 July 2018

1 reference

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Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease

7 July 2018

1 reference

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Inducible expression of chimeric EWS/ETS proteins confers Ewing's family tumor-like phenotypes to human mesenchymal progenitor cells

7 July 2018

1 reference

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Spontaneous expression of embryonic factors and p53 point mutations in aged mesenchymal stem cells: a model of age-related tumorigenesis in mice

7 July 2018

1 reference

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Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway

7 July 2018

1 reference

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Sarcomas: genetics, signalling, and cellular origins. Part 1: The fellowship of TET.

7 July 2018

1 reference

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Mesenchymal stem cell features of Ewing tumors

7 July 2018

1 reference

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A conditional mouse model of synovial sarcoma: insights into a myogenic origin

7 July 2018

1 reference

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Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724575

Murine but not human mesenchymal stem cells generate osteosarcoma-like lesions in the lung

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724575

In vitro transformation of mesenchymal stem cells by oncogenic H-rasVal12.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724575

Sarcoma derived from cultured mesenchymal stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724575

Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724575

Development of Ewing's sarcoma from primary bone marrow-derived mesenchymal progenitor cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724575

Outgrowth of a transformed cell population derived from normal human BM mesenchymal stem cell culture.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724575

Ewing's sarcoma and primitive neuroectodermal family of tumors.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724575

Adult human mesenchymal stem cell as a target for neoplastic transformation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724575

Mechanisms of sarcoma development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724575

Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: osteosarcoma and related tumors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724575

Different telomere damage signaling pathways in human and mouse cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724575

The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724575

An osteosarcoma zebrafish model implicates Mmp-19 and Ets-1 as well as reduced host immune response in angiogenesis and migration.

7 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3329-3-10

Deficiency in p53 but not retinoblastoma induces the transformation of mesenchymal stem cells in vitro and initiates leiomyosarcoma in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3329-3-10

Study of oncogenic transformation in ex vivo expanded mesenchymal cells, from paediatric bone marrow.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3329-3-10

Long-term cultures of bone marrow-derived human mesenchymal stem cells frequently undergo spontaneous malignant transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3329-3-10

Human bone marrow derived mesenchymal stem cells do not undergo transformation after long-term in vitro culture and do not exhibit telomere maintenance mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3329-3-10

c-MYC overexpression with loss of Ink4a/Arf transforms bone marrow stromal cells into osteosarcoma accompanied by loss of adipogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3329-3-10

Spontaneous transformation of cultured mouse bone marrow-derived stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3329-3-10

In vitro expanded bone marrow-derived murine (C57Bl/KaLwRij) mesenchymal stem cells can acquire CD34 expression and induce sarcoma formation in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3329-3-10

Transformation potential of bone marrow stromal cells into undifferentiated high-grade pleomorphic sarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3329-3-10

Systematic chromosomal aberrations found in murine bone marrow-derived mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3329-3-10

A spatially and temporally restricted mouse model of soft tissue sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3329-3-10

Osteosarcoma derived from donor stem cells carrying the Norrie's disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3329-3-10

Accumulated chromosomal instability in murine bone marrow mesenchymal stem cells leads to malignant transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3329-3-10

Expression of the EWS/FLI-1 oncogene in murine primary bone-derived cells Results in EWS/FLI-1-dependent, ewing sarcoma-like tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3329-3-10

Low oxygen tension maintains multipotency, whereas normoxia increases differentiation of mouse bone marrow stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3329-3-10

Mechanisms promoting physiological cells progression into tumorigenesis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724575

Synovial sarcoma is a stem cell malignancy.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724575

Spontaneous human adult stem cell transformation.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724575

c-fos expression induces bone tumors in transgenic mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724575

Cooperation of oncogenic K-ras and p53 deficiency in pleomorphic rhabdomyosarcoma development in adult mice

26 October 2018

1 reference

12 December 2020

Retraction: Spontaneous human adult stem cell transformation

1 reference

12 December 2020

Osteosarcoma after allogeneic bone marrow transplantation. A report of four cases from the Cooperative Osteosarcoma Study Group (COSS)

1 reference

12 December 2020

Liposarcoma initiated by FUS/TLS-CHOP: the FUS/TLS domain plays a critical role in the pathogenesis of liposarcoma

1 reference

12 December 2020

The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas

1 reference

12 December 2020

Ewing sarcoma family of tumors

1 reference

12 December 2020

Spontaneous Malignant Transformation of Human Mesenchymal Stem Cells Reflects Cross-Contamination: Putting the Research Field on Track - Letter

1 reference

12 December 2020

Identifiers

DOI

10.1186/2045-3329-3-10

1 reference

Dimensions Publication ID

3 August 2017

0 references

1 reference

3 August 2017

1 reference