FUS-DDIT3 prevents the development of adipocytic precursors in liposarcoma by repressing PPARgamma and C/EBPalpha and activating eIF4E. (Q33348653)

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9 January 2020

title

FUS-DDIT3 prevents the development of adipocytic precursors in liposarcoma by repressing PPARgamma and C/EBPalpha and activating eIF4E (English)

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9 January 2020

author

Manuel Sanchez-Martin

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9 January 2020

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9 January 2020

Isidro Sanchez-garcia

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9 January 2020

author name string

Pedro A Pérez-Mancera

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9 January 2020

Camino Bermejo-Rodríguez

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9 January 2020

Fernando Abollo-Jiménez

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9 January 2020

language of work or name

English

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publication date

2 July 2008

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9 January 2020

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volume

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issue

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9 January 2020

page(s)

e2569

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Creative Commons Attribution 4.0 International

9 January 2020

start time

2 July 2008

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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Human translocation liposarcoma-CCAAT/enhancer binding protein (C/EBP) homologous protein (TLS-CHOP) oncoprotein prevents adipocyte differentiation by directly interfering with C/EBPbeta function

21 June 2018

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21 June 2018

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21 January 2018

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Expression of the FUS-CHOP fusion protein in primary mesenchymal progenitor cells gives rise to a model of myxoid liposarcoma.

21 January 2018

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Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity.

21 January 2018

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A BCR-ABL(p190) fusion gene made by homologous recombination causes B-cell acute lymphoblastic leukemias in chimeric mice with independence of the endogenous bcr product

21 January 2018

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12 December 2020

Fat-specific FUS-DDIT3-transgenic mice establish PPAR inactivation is required to liposarcoma development

1 reference

12 December 2020

Liposarcoma initiated by FUS/TLS-CHOP: the FUS/TLS domain plays a critical role in the pathogenesis of liposarcoma

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12 December 2020

Expression of the FUS domain restores liposarcoma development in CHOP transgenic mice

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12 December 2020

Temperature-dependent localization of TLS-CHOP to splicing factor compartments

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12 December 2020

10.1371/JOURNAL.PONE.0002569

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18596980%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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9 January 2020

PubMed publication ID

18596980

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18596980%20AND%20SRC:MED&resulttype=core&format=json