Cinnabarinic acid, an endogenous metabolite of the kynurenine pathway, activates type 4 metabotropic glutamate receptors (Q34252595)

31 July 2017

title

Cinnabarinic acid, an endogenous metabolite of the kynurenine pathway, activates type 4 metabotropic glutamate receptors (English)

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31 July 2017

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Cinnabarinic acid

31 May 2024

F Fazio

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31 July 2017

L Lionetto

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31 July 2017

G Molinaro

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31 July 2017

H O Bertrand

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31 July 2017

F Acher

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31 July 2017

R T Ngomba

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31 July 2017

S Notartomaso

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31 July 2017

M Curini

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31 July 2017

O Rosati

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31 July 2017

P Scarselli

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31 July 2017

R Di Marco

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31 July 2017

G Battaglia

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31 July 2017

V Bruno

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31 July 2017

M Simmaco

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31 July 2017

J P Pin

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31 July 2017

F Nicoletti

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31 July 2017

C Goudet

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31 July 2017

publication date

6 February 2012

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31 July 2017

published in

Molecular Pharmacology

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

643-656

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(-)-PHCCC, a positive allosteric modulator of mGluR4: characterization, mechanism of action, and neuroprotection.

31 July 2017

cites work

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Interferon-gamma-induced conversion of tryptophan: immunologic and neuropsychiatric aspects

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Pharmacological agents acting at subtypes of metabotropic glutamate receptors

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Common and selective molecular determinants involved in metabotopic glutamate receptor agonist activity

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relationship to clinical and neurological status

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Induction and temporal changes of osteopontin mRNA and protein in the brain following systemic lipopolysaccharide injection

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

A virtual screening hit reveals new possibilities for developing group III metabotropic glutamate receptor agonists

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Protein measurement with the Folin phenol reagent

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Molecular determinants of high affinity binding to group III metabotropic glutamate receptors

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Endogenous kynurenines as targets for drug discovery and development

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenate and have sedative and anticonvulsant activities

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

The use of knock-out mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/neuroprotection

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Xanthurenic acid distribution, transport, accumulation and release in the rat brain.

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Oxidative reactivity of the tryptophan metabolites 3-hydroxyanthranilate, cinnabarinate, quinolinate and picolinate

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Cinnabarinic acid generated from 3-hydroxyanthranilic acid strongly induces apoptosis in thymocytes through the generation of reactive oxygen species and the induction of caspase

2 references

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

31 May 2024

https://opencitations.net/index/api/v1/citations/10.1002/JCB.21384

Exciting times beyond the brain: metabotropic glutamate receptors in peripheral and non-neural tissues

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Interaction of novel positive allosteric modulators of metabotropic glutamate receptor 5 with the negative allosteric antagonist site is required for potentiation of receptor responses.

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

The activation of inositol phospholipid metabolism as a signal-transducing system for excitatory amino acids in primary cultures of cerebellar granule cells.

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Temporal and depolarization-induced changes in the absolute amounts of mRNAs encoding metabotropic glutamate receptors in cerebellar granule neurons in vitro

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

The efficiency of systematic sampling in stereology--reconsidered.

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

A glycine site associated with N-methyl-D-aspartic acid receptors: characterization and identification of a new class of antagonists

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

N-{4-Chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-2-hydroxybenzamide (CPPHA) acts through a novel site as a positive allosteric modulator of group 1 metabotropic glutamate receptors

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Probing the ligand-binding domain of the mGluR4 subtype of metabotropic glutamate receptor

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Quinolinic acid: a potent endogenous excitant at amino acid receptors in CNS

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors.

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigrostriatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation.

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Selective activation of mGlu4 metabotropic glutamate receptors is protective against excitotoxic neuronal death

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Metabotropic glutamate receptors in the basal ganglia motor circuit

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Manipulation of brain kynurenines: glial targets, neuronal effects, and clinical opportunities

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Amino-pyrrolidine tricarboxylic acids give new insight into group III metabotropic glutamate receptor activation mechanism

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Some metabotropic glutamate receptor ligands reduce kynurenate synthesis in rats by intracellular inhibition of kynurenine aminotransferase II

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

CTLA-4-Ig regulates tryptophan catabolism in vivo.

1 reference

31 May 2024

https://opencitations.net/index/api/v1/references/10.1124/MOL.111.074765

Identifiers

DOI

10.1124/MOL.111.074765

1 reference

release_3klb7bhywnf63ppitsfjog4j4a

31 July 2017

Fatcat ID

1 reference

https://api.fatcat.wiki/v0/release/3klb7bhywnf63ppitsfjog4j4a

Fatcat

reference URL

mapped directly with Wikidata item

24 November 2022

based on heuristic

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