Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigrostriatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. (Q48478225)

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scientific article published in July 2006

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English	Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigrostriatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.	scientific article published in July 2006

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PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/16822979

Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigrostriatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (English)

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11 May 2020

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Giuseppe Battaglia

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11 May 2020

Francesca Biagioni

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11 May 2020

Carla L Busceti

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11 May 2020

Anna Traficante

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11 May 2020

Ferdinando Nicoletti

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11 May 2020

Valeria Maria Gloria Bruno

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11 May 2020

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Gemma Molinaro

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11 May 2020

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publication date

1 July 2006

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11 February 2018

http://europepmc.org/abstract/MED/16822979

Journal of Neuroscience

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11 May 2020

26

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11 May 2020

27

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11 May 2020

7222-7229

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11 May 2020

In vivo effects of new inhibitors of catechol-O-methyl transferase

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https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Pathophysiology of L-dopa-induced dyskinesias.

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https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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The group II metabotropic glutamate receptor agonist, DCG-IV, alleviates akinesia following intranigral or intraventricular administration in the reserpine-treated rat

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https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Activation of striatal group II metabotropic glutamate receptors has a differential effect on dopamine-D1 and -D2 receptor antagonist-induced hypokinesia in the rat

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https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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The pharmacological therapeutic management of levodopa-induced dyskinesias in patients with Parkinson's disease

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https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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The role of metabotropic glutamate receptor (mGluR) ligands in parkinsonian muscle rigidity

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https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Group II metabotropic glutamate receptor activation protects striatal dopaminergic nerve terminals against MPP+-induced neurotoxicity along with brain-derived neurotrophic factor induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Molecular determinants of metabotropic glutamate receptor signaling.

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https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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(S)-4C3HPG, a mixed group I mGlu receptor antagonist and a group II agonist, administered intrastriatally, counteracts parkinsonian-like muscle rigidity in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

based on heuristic

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Group I mGluR antagonist AIDA protects nigral DA cells from MPTP-induced injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

based on heuristic

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Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Chronic but not acute treatment with a metabotropic glutamate 5 receptor antagonist reverses the akinetic deficits in a rat model of parkinsonism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Protective role of group-II metabotropic glutamate receptors against nigro-striatal degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

based on heuristic

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Group III metabotropic glutamate receptor-mediated modulation of the striatopallidal synapse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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(-)-PHCCC, a positive allosteric modulator of mGluR4: characterization, mechanism of action, and neuroprotection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

based on heuristic

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Allosteric modulation of group III metabotropic glutamate receptor 4: A potential approach to Parkinson's disease treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Activation of group III metabotropic glutamate receptors in selected regions of the basal ganglia alleviates akinesia in the reserpine-treated rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Activation of group III metabotropic glutamate receptors presynaptically reduces both GABAergic and glutamatergic transmission in the rat globus pallidus

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https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Protein measurement with the Folin phenol reagent

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Risk factors for dopaminergic neuron loss in human alpha-synuclein transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Group III metabotropic glutamate-receptor-mediated modulation of excitatory transmission in rodent substantia nigra pars compacta dopamine neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Metabotropic glutamate receptors in the basal ganglia motor circuit

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Correlation between (3H)dopamine specific uptake and (3H)GBR 12783 specific binding during the maturation of rat striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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The metabotropic glutamate receptors: structure and functions

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https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Glutamatergic drugs in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Blockade of 1-methyl-4-phenylpyridinium ion (MPP+) nigral toxicity in the rat by prior decortication or MK-801 treatment: a stereological estimate of neuronal loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Effects of noradrenergic lesions on MPTP/MPP+ kinetics and MPTP-induced nigrostriatal dopamine depletions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Mechanisms of MPTP toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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LY354740, a group II metabotropic glutamate receptor agonist with potential antiparkinsonian properties in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

based on heuristic

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Role of glutamate in neurodegeneration of dopamine neurons in several animal models of parkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16822979

12 December 2020

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Identifiers

10.1523/JNEUROSCI.1595-06.2006

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673941&resulttype=core&format=json

11 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673941&resulttype=core&format=json

11 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673941&resulttype=core&format=json

11 May 2020

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