Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists (Q34036974)

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English	Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

Anne-Sophie Bessis

1

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Europe PubMed Central

PubMed publication ID

30 July 2017

Philippe Rondard

2

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Europe PubMed Central

PubMed publication ID

30 July 2017

Florence Gaven

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Isabelle Brabet

4

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Europe PubMed Central

PubMed publication ID

30 July 2017

Nicolas Triballeau

5

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Laurent Prezeau

6

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Francine Acher

7

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Europe PubMed Central

PubMed publication ID

30 July 2017

Jean-Philippe Pin

8

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Europe PubMed Central

PubMed publication ID

30 July 2017

language of work or name

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publication date

31 July 2002

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Europe PubMed Central

PubMed publication ID

30 July 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

PubMed publication ID

30 July 2017

99

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Europe PubMed Central

PubMed publication ID

30 July 2017

17

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Europe PubMed Central

PubMed publication ID

30 July 2017

11097-11102

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123216

5 July 2018

Molecular determinants of high affinity binding to group III metabotropic glutamate receptors

1 reference

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5 July 2018

Ligand-induced signal transduction within heterodimeric GABA(B) receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123216

5 July 2018

Identification of essential residues involved in the glutamate binding pocket of the group II metabotropic glutamate receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123216

5 July 2018

Structural insights into the ligand binding domains of membrane bound guanylyl cyclases and natriuretic peptide receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123216

5 July 2018

Allosteric activation of a spring-loaded natriuretic peptide receptor dimer by hormone

1 reference

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5 July 2018

Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function

1 reference

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5 July 2018

Molecular determinants of metabotropic glutamate receptor signaling.

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5 July 2018

Construction of a high affinity zinc binding site in the metabotropic glutamate receptor mGluR1: noncompetitive antagonism originating from the amino-terminal domain of a family C G-protein-coupled receptor

1 reference

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5 July 2018

Covalent and noncovalent interactions mediate metabotropic glutamate receptor mGlu5 dimerization.

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5 July 2018

Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123216

5 July 2018

Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123216

5 July 2018

Cryptic dimer interface and domain organization of the extracellular region of metabotropic glutamate receptor subtype 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123216

5 July 2018

Pharmacological characterization of the rat metabotropic glutamate receptor type 8a revealed strong similarities and slight differences with the type 4a receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123216

5 July 2018

Structural adaptation to selective pressure for altered ligand specificity in the Pseudomonas aeruginosa amide receptor, amiC

1 reference

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5 July 2018

Probing the ligand-binding domain of the mGluR4 subtype of metabotropic glutamate receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123216

5 July 2018

Identification of the cysteine residues in the amino-terminal extracellular domain of the human Ca(2+) receptor critical for dimerization. Implications for function of monomeric Ca(2+) receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123216

5 July 2018

Molecular tinkering of G protein-coupled receptors: an evolutionary success

1 reference

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5 July 2018

GABA(B)-receptor subtypes assemble into functional heteromeric complexes.

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5 July 2018

Heterodimerization is required for the formation of a functional GABA(B) receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123216

5 July 2018

GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123216

5 July 2018

Comparative effect of L-CCG-I, DCG-IV and gamma-carboxy-L-glutamate on all cloned metabotropic glutamate receptor subtypes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123216

5 July 2018

Structure of a glutamate-receptor ligand-binding core in complex with kainate

1 reference

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5 July 2018

The G protein-coupling profile of metabotropic glutamate receptors, as determined with exogenous G proteins, is independent of their ligand recognition domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123216

5 July 2018

Synthesis and Pharmacological Characterization of Aminocyclopentanetricarboxylic Acids: New Tools to Discriminate between Metabotropic Glutamate Receptor Subtypes

1 reference

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5 July 2018

Coupling of metabotropic glutamate receptors 2 and 4 to G alpha 15, G alpha 16, and chimeric G alpha q/i proteins: characterization of new antagonists

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123216

5 July 2018

Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha

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5 July 2018

The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins

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Role of the large extracellular domain of metabotropic glutamate receptors in agonist selectivity determination

1 reference

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Crystal structure of AmiC: the controller of transcription antitermination in the amidase operon of Pseudomonas aeruginosa

1 reference

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Three-dimensional model of the extracellular domain of the type 4a metabotropic glutamate receptor: new insights into the activation process

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A simple method to transfer plasmid DNA into neuronal primary cultures: functional expression of the mGlu5 receptor in cerebellar granule cells

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Ligand-dependent conformational plasticity of the periplasmic histidine-binding protein HisJ. Involvement in transport specificity

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21 January 2018

The histidine-binding protein undergoes conformational changes in the absence of ligand as analyzed with conformation-specific monoclonal antibodies

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Extended glutamate activates metabotropic receptor types 1, 2 and 4: selective features at mGluR4 binding site

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Homology modeling of metabotropic glutamate receptors. (mGluRs) structural motifs affecting binding modes and pharmacological profile of mGluR1 agonists and competitive antagonists

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Mapping the agonist-binding site of GABAB type 1 subunit sheds light on the activation process of GABAB receptors

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Metabotropic glutamate receptor 5 is a disulfide-linked dimer

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A model for the functioning of family 3 GPCRs

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A novel site on the Galpha -protein that recognizes heptahelical receptors

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Ubiquitination of protein kinase C-alpha and degradation by the proteasome

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21 January 2018

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10.1073/PNAS.162138699

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Europe PubMed Central

PubMed publication ID

30 July 2017

2002PNAS...9911097B

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Europe PubMed Central

PubMed publication ID

30 July 2017

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30 July 2017

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