Constitutive activation of epidermal growth factor receptor promotes tumorigenesis of Cr(VI)-transformed cells through decreased reactive oxygen species and apoptosis resistance development (Q28386290)

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English	Constitutive activation of epidermal growth factor receptor promotes tumorigenesis of Cr(VI)-transformed cells through decreased reactive oxygen species and apoptosis resistance development	scientific article

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Constitutive activation of epidermal growth factor receptor promotes tumorigenesis of Cr(VI)-transformed cells through decreased reactive oxygen species and apoptosis resistance development (English)

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reactive oxygen species

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9

object named as

Xianglin Shi

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object named as

Young-Ok Son

5

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10

object named as

Zhuo Zhang

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Poyil Pratheeshkumar

7

object named as

Poyil Pratheeshkumar

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author name string

Donghern Kim

1

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Jin Dai

2

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Leonard Yenwong Fai

3

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Hua Yao

4

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Lei Wang

6

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Kazuya Kondo

8

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language of work or name

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publication date

23 January 2015

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Journal of Biological Chemistry

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290

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4

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2213-24

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Multifunctional role of Bcl-2 in malignant transformation and tumorigenesis of Cr(VI)-transformed lung cells

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20 March 2017

NADPH oxidase activation is required in reactive oxygen species generation and cell transformation induced by hexavalent chromium

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20 March 2017

Lung inflammation, injury, and proliferative response after repetitive particulate hexavalent chromium exposure

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Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity

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Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants

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Metal-induced oxidative stress and signal transduction

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Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways

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20 March 2017

Untangling the ErbB signalling network

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20 March 2017

Role of reactive oxygen species and p53 in chromium(VI)-induced apoptosis

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Mechanisms and Functions of Cell Death

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The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

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7 April 2017

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

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7 April 2017

Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer

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29 September 2017

The impact of reactive oxygen species on anticancer therapeutic strategies

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Redox regulation of protein kinases

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29 September 2017

NADPH oxidase biology and the regulation of tyrosine kinase receptor signaling and cancer drug cytotoxicity

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Erlotinib-mediated inhibition of EGFR signaling induces metabolic oxidative stress through NOX4.

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29 September 2017

Anti-apoptosis and cell survival: A review

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EGFR mutations and lung cancer

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Lung Adenocarcinoma From East Asian Never-Smokers Is a Disease Largely Defined by Targetable Oncogenic Mutant Kinases

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29 September 2017

Hexavalent chromium induced ROS formation, Akt, NF-kappaB, and MAPK activation, and TNF-alpha and IL-1alpha production in keratinocytes.

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29 September 2017

NADPH oxidase NOX1 controls autocrine growth of liver tumor cells through up-regulation of the epidermal growth factor receptor pathway

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Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition.

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29 September 2017

Reactive oxygen species mediate mitogenic growth factor signaling pathways in human leiomyoma smooth muscle cells

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29 September 2017

Human bronchial epithelial cells malignantly transformed by hexavalent chromium exhibit an aneuploid phenotype but no microsatellite instability.

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29 September 2017

Magnolol induces apoptosis via inhibiting the EGFR/PI3K/Akt signaling pathway in human prostate cancer cells

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29 September 2017

AKT/mTOR pathway activation and BCL-2 family proteins modulate the sensitivity of human small cell lung cancer cells to RAD001.

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29 September 2017

The epidermal growth factor receptor ligands at a glance

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29 September 2017

Oxidative stress and chromium(VI) carcinogenesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303672

29 September 2017

Hypersensitivity to chromium-induced DNA damage correlates with constitutive deregulation of upstream p53 kinases in p21-/- HCT116 colon cancer cells

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29 September 2017

EGFR kinase domain mutations - functional impact and relevance for lung cancer therapy

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29 September 2017

Protein tyrosine phosphorylation and reversible oxidation: two cross-talking posttranslation modifications

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29 September 2017

Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer

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29 September 2017

Inhibition of EGFR/PI3K/AKT cell survival pathway promotes TSA's effect on cell death and migration in human ovarian cancer cells

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29 September 2017

BCL2 family in DNA damage and cell cycle control

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29 September 2017

The biology of epidermal growth factor receptor in lung cancer

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29 September 2017

Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor

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29 September 2017

EGF receptor ligands

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29 September 2017

Cell apoptosis induced by carcinogenic metals

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21 January 2018

Reflections on hexavalent chromium: health hazards of an industrial heavyweight

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29 September 2017

Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein.

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29 September 2017

Apoptosis and carcinogenesis

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29 September 2017

Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents

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29 September 2017

One hundred years of chromium and cancer: a review of epidemiological evidence and selected case reports

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29 September 2017

Reactive oxygen species generation is involved in epidermal growth factor receptor transactivation through the transient oxidization of Src homology 2-containing tyrosine phosphatase in endothelin-1 signaling pathway in rat cardiac fibroblasts.

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21 January 2018

Chromium (V) and hydroxyl radical formation during the glutathione reductase-catalyzed reduction of chromium (VI).

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UVB-induced epidermal growth factor receptor phosphorylation is critical for downstream signaling and keratinocyte survival

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12 December 2020

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Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival

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12 December 2020

based on heuristic

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Chromium, nickel and welding

1 reference

https://pubmed.ncbi.nlm.nih.gov/25477514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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