Erlotinib-mediated inhibition of EGFR signaling induces metabolic oxidative stress through NOX4. (Q35553145)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Erlotinib-mediated inhibition of EGFR signaling induces metabolic oxidative stress through NOX4 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Zita A Sibenaller

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Kevin P Orcutt

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Arlene D Parsons

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Peter M Scarbrough

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Yueming Zhu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Arya Sobhakumari

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Werner W Wilke

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Amanda L Kalen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Francis J Miller

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Andrean L Simons

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

language of work or name

English

0 references

publication date

11 April 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

page(s)

3932-3940

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

EGFR tyrosine kinase inhibitors and multidrug resistance: perspectives

28 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Metastasis: cancer cell's escape from oxidative stress.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Inhibition of glutathione and thioredoxin metabolism enhances sensitivity to perifosine in head and neck cancer cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Subcellular localization of Nox4 and regulation in diabetes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Reactive oxygen species-dependent signaling regulates cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Roles of Nox1 and other Nox isoforms in cancer development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Nox4 NADPH oxidase mediates oxidative stress and apoptosis caused by TNF-alpha in cerebral vascular endothelial cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

EGFR targeting of solid tumors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Erlotinib, an effective epidermal growth factor receptor tyrosine kinase inhibitor, induces p27KIP1 up-regulation and nuclear translocation in association with cell growth inhibition and G1/S phase arrest in human non-small-cell lung cancer cell lin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Cellular responses to EGFR inhibitors and their relevance to cancer therapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

The epidermal growth factor receptor (EGFR) in head and neck cancer: its role and treatment implications

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Targeting the epidermal growth factor receptor by erlotinib (Tarceva) for the treatment of esophageal cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Erlotinib induces cell cycle arrest and apoptosis in hepatocellular cancer cells and enhances chemosensitivity towards cytostatics

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Protein measurement with the Folin phenol reagent

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Persistent oxidative stress in cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Cell division in normal and transformed cells: The possible role of superoxide and hydrogen peroxide

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Superoxide dismutase and superoxide radical in Morris hepatomas.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Cell differentation, aging and cancer: The possible roles of superoxide and superoxide dismutases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Cytotoxicity and metabolism of 4-hydroxy-2-nonenal and 2-nonenal in H2O2-resistant cell lines. Do aldehydic by-products of lipid peroxidation contribute to oxidative stress?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Production of large amounts of hydrogen peroxide by human tumor cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Effects of antioxidant enzyme overexpression on the invasive phenotype of hamster cheek pouch carcinoma cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

Elevated levels of transforming growth factor alpha and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217301

UVB-induced epidermal growth factor receptor phosphorylation is critical for downstream signaling and keratinocyte survival

26 September 2018

1 reference

12 December 2020

Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival

1 reference

12 December 2020

Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine

1 reference

12 December 2020

Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis

1 reference

12 December 2020

Overexpression of catalase in cytosolic or mitochondrial compartment protects HepG2 cells against oxidative injury

1 reference

12 December 2020

10.1158/0008-5472.CAN-10-3425

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

21482679

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21482679%20AND%20SRC:MED&resulttype=core&format=json