Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation (Q28118966)

4 January 2017

title

Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation (English)

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amyotrophic lateral sclerosis

4 January 2017

main subject

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GOA release 2020-03-11

parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

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GOA release 2020-03-11

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Yvette C. Wong

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4 January 2017

Erika L. F. Holzbaur

series ordinal

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4 January 2017

language of work or name

English

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publication date

21 October 2014

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Proceedings of the National Academy of Sciences of the United States of America

4 January 2017

published in

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4 January 2017

volume

111

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4 January 2017

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4 January 2017

page(s)

E4439–4448

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describes a project that uses

4 January 2017

ImageJ

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4210283/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis

20 March 2017

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Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

20 March 2017

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p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

20 March 2017

1 reference

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Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Alterations in the common fragile site gene Parkin in ovarian and other cancers

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.1405752111

Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin.

21 January 2018

1 reference

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Chromophore-assisted light inactivation (CALI) using the phototoxic fluorescent protein KillerRed.

21 January 2018

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Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy.

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1073/PNAS.1405752111

1 reference

ADS bibcode

2014PNAS..111E4439W

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1 reference

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