p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria (Q34269257)

1 August 2017

title

p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria (English)

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1 August 2017

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Masaaki Komatsu

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Nobutaka Hattori

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1 August 2017

Kei Okatsu

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1 August 2017

Keiko Saisho

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1 August 2017

Midori Shimanuki

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1 August 2017

Kazuto Nakada

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1 August 2017

Hiroshi Shitara

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1 August 2017

Yu-Shin Sou

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1 August 2017

Mayumi Kimura

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1 August 2017

Shigeto Sato

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1 August 2017

Keiji Tanaka

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1 August 2017

Noriyuki Matsuda

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1 August 2017

publication date

2 July 2010

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1 August 2017

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

887-900

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Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy

1 August 2017

cites work

1 reference

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PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Physiological significance of selective degradation of p62 by autophagy

6 July 2018

1 reference

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6 July 2018

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PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Does impairment of the ubiquitin-proteasome system or the autophagy-lysosome pathway predispose individuals to neurodegenerative disorders such as Parkinson's disease?

6 July 2018

1 reference

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Control of mitochondrial transport and localization in neurons.

6 July 2018

1 reference

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PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway.

6 July 2018

1 reference

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Listeria monocytogenes ActA-mediated escape from autophagic recognition

6 July 2018

1 reference

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A role for ubiquitin in selective autophagy

6 July 2018

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Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome

6 July 2018

1 reference

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Analysis of nondegradative protein ubiquitylation with a monoclonal antibody specific for lysine-63-linked polyubiquitin

6 July 2018

1 reference

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Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes

6 July 2018

1 reference

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Structural basis of target recognition by Atg8/LC3 during selective autophagy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

The N-terminus and Phe52 residue of LC3 recruit p62/SQSTM1 into autophagosomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Structural basis for sorting mechanism of p62 in selective autophagy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Ubiquitin-proteasome system dysfunction in Parkinson's disease: current evidence and controversies

6 July 2018

1 reference

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Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

6 July 2018

1 reference

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The axonal transport of mitochondria.

6 July 2018

1 reference

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Opinion: What is the role of protein aggregation in neurodegeneration?

6 July 2018

1 reference

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Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

6 July 2018

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Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics

6 July 2018

1 reference

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Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins

6 July 2018

1 reference

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Themes and variations on ubiquitylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Aggresomes: a cellular response to misfolded proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Kinesin and Dynein Superfamily Proteins and the Mechanism of Organelle Transport

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Nondroplet ultrastructural demonstration of cytochrome oxidase activity with a polymerizing osmiophilic reagent, diaminobenzidine (DAB).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Depletion of 26S proteasomes in mouse brain neurons causes neurodegeneration and Lewy-like inclusions resembling human pale bodies.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Controlled synthesis of polyubiquitin chains

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Alterations in the common fragile site gene Parkin in ovarian and other cancers

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970908

Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20604804

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

In situ and in vitro study of colocalization and segregation of alpha-synuclein, ubiquitin, and lipids in Lewy bodies

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20604804

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tissue specificity in cytochrome c oxidase deficient myopathy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20604804

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1365-2443.2010.01426.X

1 reference

1 August 2017

1 reference

1 August 2017

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