Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage (Q27680666)

25 June 2017

title

Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage (English)

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25 June 2017

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Damien Bonnard

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Alessia Zamborlini

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Erwann Le Rouzic

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25 June 2017

Sophie Chasset

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25 June 2017

Jean-Michel Bruneau

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25 June 2017

Francis Chevreuil

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25 June 2017

Frédéric Le Strat

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25 June 2017

Juliette Nguyen

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Roxane Beauvoir

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25 June 2017

Céline Amadori

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25 June 2017

Julie Brias

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Sophie Vomscheid

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25 June 2017

Sylvia Eiler

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25 June 2017

Nicolas Lévy

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25 June 2017

Olivier Delelis

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25 June 2017

Eric Deprez

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25 June 2017

Ali Saïb

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25 June 2017

Stéphane Emiliani

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25 June 2017

Marc Ruff

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25 June 2017

Benoit Ledoussal

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25 June 2017

François Moreau

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25 June 2017

Richard Benarous

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25 June 2017

publication date

21 November 2013

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25 June 2017

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25 June 2017

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25 June 2017

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144

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describes a project that uses

25 June 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4222603/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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20 March 2017

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20 March 2017

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HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells

20 March 2017

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HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75.

29 September 2017

1 reference

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The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding

29 September 2017

1 reference

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Colinearity of Reverse Transcriptase Inhibitor Resistance Mutations Detected by Population-Based Sequencing

29 September 2017

1 reference

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Analysis of early human immunodeficiency virus type 1 DNA synthesis by use of a new sensitive assay for quantifying integrated provirus

29 September 2017

1 reference

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Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding

29 September 2017

1 reference

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Catalytic domain of human immunodeficiency virus type 1 integrase: identification of a soluble mutant by systematic replacement of hydrophobic residues

29 September 2017

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LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions

29 September 2017

1 reference

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HeLa-LAV, an epithelial cell line stably infected with HIV-1

2 June 2018

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Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication

2 June 2018

1 reference

Crossref

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Development of an AlphaScreen-based HIV-1 integrase dimerization assay for discovery of novel allosteric inhibitors

21 January 2018

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Crossref

https://api.crossref.org/works/10.1186%2F1742-4690-10-144

HIV-1 integrase preassembled on donor DNA is refractory to activity stimulation by LEDGF/p75.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1186/1742-4690-10-144

1 reference

Dimensions Publication ID

25 June 2017

1040153847

0 references

OpenCitations bibliographic resource ID

1636983

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1636983

1 reference