Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity (Q24316318)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19369943%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity (English)

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26 January 2020

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26 January 2020

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26 January 2020

Yefim Manevich

1 reference

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26 January 2020

Roderick Bronson

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26 January 2020

Juxiang Cao

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26 January 2020

Jennifer Schulte

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26 January 2020

Agnieszka Zagozdzon

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26 January 2020

Craig Beeson

1 reference

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26 January 2020

Carola A Neumann

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26 January 2020

language of work or name

English

0 references

publication date

16 April 2009

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26 January 2020

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26 January 2020

volume

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26 January 2020

issue

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26 January 2020

page(s)

1505-1517

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Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway

26 January 2020

cites work

1 reference

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The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity

19 March 2017

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Dimer-oligomer interconversion of wild-type and mutant rat 2-Cys peroxiredoxin: disulfide formation at dimer-dimer interfaces is not essential for decamerization

19 March 2017

1 reference

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Regulation of reactive oxygen species, DNA damage, and c-Myc function by peroxiredoxin 1

19 March 2017

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Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression

19 March 2017

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Inactivation of human peroxiredoxin I during catalysis as the result of the oxidation of the catalytic site cysteine to cysteine-sulfinic acid

19 March 2017

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Crystal structure of decameric 2-Cys peroxiredoxin from human erythrocytes at 1.7 A resolution

19 March 2017

1 reference

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Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

19 March 2017

1 reference

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

19 March 2017

1 reference

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SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

19 March 2017

1 reference

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Thioredoxin-dependent peroxide reductase from yeast

19 March 2017

1 reference

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

19 March 2017

1 reference

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Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

7 April 2017

1 reference

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Reversible inactivation of the tumor suppressor PTEN by H2O2

7 April 2017

1 reference

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The role of PTEN signaling perturbations in cancer and in targeted therapy

7 April 2017

1 reference

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Are peroxiredoxins tumor suppressors?

27 September 2017

1 reference

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Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner.

27 September 2017

1 reference

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Cell signaling. H2O2, a necessary evil for cell signaling

27 September 2017

1 reference

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The deficiency of Akt1 is sufficient to suppress tumor development in Pten+/- mice

27 September 2017

1 reference

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Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane

27 September 2017

1 reference

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Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance

27 September 2017

1 reference

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Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors

27 September 2017

1 reference

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Reversible oxidation of the active site cysteine of peroxiredoxins to cysteine sulfinic acid. Immunoblot detection with antibodies specific for the hyperoxidized cysteine-containing sequence

27 September 2017

1 reference

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Redox regulation of PI 3-kinase signalling via inactivation of PTEN

27 September 2017

1 reference

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Membrane-binding and activation mechanism of PTEN.

27 September 2017

1 reference

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Enumeration of the simian virus 40 early region elements necessary for human cell transformation

27 September 2017

1 reference

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Specific protection against breast cancers by cyclin D1 ablation

27 September 2017

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Akt/PKB activity is required for Ha-Ras-mediated transformation of intestinal epithelial cells

27 September 2017

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Analysis of the cellular functions of PTEN using catalytic domain and C-terminal mutations: differential effects of C-terminal deletion on signalling pathways downstream of phosphoinositide 3-kinase

27 September 2017

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Inhibition of H-Ras transformation by the PTEN/MMAC1/TEP1 tumor suppressor gene

27 September 2017

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Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia

27 September 2017

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Dimerization of thiol-specific antioxidant and the essential role of cysteine 47.

27 September 2017

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Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo

27 September 2017

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Electrostatic evaluation of the signature motif (H/V)CX5R(S/T) in protein-tyrosine phosphatases.

27 September 2017

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Active site labeling of the Yersinia protein tyrosine phosphatase: the determination of the pKa of the active site cysteine and the function of the conserved histidine 402.

27 September 2017

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Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity

27 September 2017

1 reference

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Transformation potential of Ras isoforms correlates with activation of phosphatidylinositol 3-kinase but not ERK.

30 May 2018

1 reference

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Activation of Akt-1 (PKB-alpha) can accelerate ErbB-2-mediated mammary tumorigenesis but suppresses tumor invasion

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.101

Prx1 suppresses radiation-induced c-Jun NH2-terminal kinase signaling in lung cancer cells through interaction with the glutathione S-transferase Pi/c-Jun NH2-terminal kinase complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.101

Motif analysis of the tumor suppressor gene MMAC/PTEN identifies tyrosines critical for tumor suppression and lipid phosphatase activity

21 January 2018

1 reference

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Structure of Helicobacter pylori catalase, with and without formic acid bound, at 1.6 A resolution

21 January 2018

1 reference

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Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.101

A Chemical Proteomics Approach to Phosphatidylinositol 3-Kinase Signaling in Macrophages

21 January 2018

1 reference

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Regulation of protein phosphatase 2A by hydrogen peroxide and glutathionylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.101

The tumor suppressor gene PTEN can regulate cardiac hypertrophy and survival

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19369943

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOJ.2009.101

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19369943%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19369943%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

PubMed publication ID

19369943

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19369943%20AND%20SRC:MED&resulttype=core&format=json