Expanding the genetic editing tool kit: ZFNs, TALENs, and CRISPR-Cas9. (Q38255828)

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scientific article published on October 2014

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English	Expanding the genetic editing tool kit: ZFNs, TALENs, and CRISPR-Cas9.	scientific article published on October 2014

Statements

instance of

scholarly article

1 reference

stated in

Europe PubMed Central

PMC publication ID

4191047

retrieved

1 September 2017

review article

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stated in

Europe PubMed Central

title

Expanding the genetic editing tool kit: ZFNs, TALENs, and CRISPR-Cas9. (English)

1 reference

stated in

Europe PubMed Central

PMC publication ID

4191047

retrieved

1 September 2017

main subject

CRISPR

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Cas9

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CRISPR-Cas method

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based on heuristic

inferred from title

author name string

Rajat M Gupta

series ordinal

1

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stated in

Europe PubMed Central

PMC publication ID

4191047

retrieved

1 September 2017

Kiran Musunuru

series ordinal

2

1 reference

stated in

Europe PubMed Central

PMC publication ID

4191047

retrieved

1 September 2017

language of work or name

English

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publication date

1 October 2014

1 reference

stated in

Europe PubMed Central

PMC publication ID

4191047

retrieved

1 September 2017

published in

Journal of Clinical Investigation

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stated in

Europe PubMed Central

PMC publication ID

4191047

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1 September 2017

volume

124

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stated in

Europe PubMed Central

PMC publication ID

4191047

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1 September 2017

issue

10

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stated in

Europe PubMed Central

PMC publication ID

4191047

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1 September 2017

page(s)

4154-4161

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Europe PubMed Central

PMC publication ID

4191047

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1 September 2017

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Targeted inversion and reversion of the blood coagulation factor 8 gene in human iPS cells using TALENs

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Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients

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Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.

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One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering

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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

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One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

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Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides

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A library of TAL effector nucleases spanning the human genome

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Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

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RNA-guided human genome engineering via Cas9

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Multiplex genome engineering using CRISPR/Cas systems

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Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells.

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Highly active zinc-finger nucleases by extended modular assembly

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Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

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A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

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A TALE nuclease architecture for efficient genome editing

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6 September 2017

Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors

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Genome editing with engineered zinc finger nucleases

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TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain

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Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases

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Targeting DNA double-strand breaks with TAL effector nucleases

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6 September 2017

Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

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Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases

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Zinc-finger nuclease-induced gene repair with oligodeoxynucleotides: wanted and unwanted target locus modifications

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6 September 2017

A simple cipher governs DNA recognition by TAL effectors

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6 September 2017

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Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

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6 September 2017

Knockout rats via embryo microinjection of zinc-finger nucleases

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6 September 2017

Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells

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6 September 2017

Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly

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6 September 2017

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

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6 September 2017

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

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6 September 2017

Unexpected failure rates for modular assembly of engineered zinc fingers

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6 September 2017

Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191047

retrieved

6 September 2017

Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191047

retrieved

6 September 2017

An improved zinc-finger nuclease architecture for highly specific genome editing

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191047

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6 September 2017

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191047

retrieved

6 September 2017

A computational study of off-target effects of RNA interference

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191047

retrieved

6 September 2017

Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191047

retrieved

6 September 2017

Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination

1 reference

stated in

PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191047

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6 September 2017

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191047

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6 September 2017

An unbiased genome-wide analysis of zinc-finger nuclease specificity

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191047

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6 September 2017

Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191047

retrieved

6 September 2017

Targeted genome editing in human repopulating haematopoietic stem cells

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191047

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23 June 2018

Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191047

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23 June 2018

Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191047

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23 June 2018

Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems.

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191047

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31 August 2018

Heritable gene targeting in the mouse and rat using a CRISPR-Cas system.

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191047

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31 August 2018

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191047

retrieved

31 August 2018

Knockout rats generated by embryo microinjection of TALENs.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191047

retrieved

31 August 2018

TAL effector RVD specificities and efficiencies

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/25271723

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Knockout mice created by TALEN-mediated gene targeting

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/25271723

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1172/JCI72992

1 reference

stated in

Europe PubMed Central

PMC publication ID

4191047

retrieved

1 September 2017

PMC publication ID

4191047

1 reference

stated in

Europe PubMed Central

PMC publication ID

4191047

retrieved

1 September 2017

PubMed publication ID

25271723

1 reference

stated in

Europe PubMed Central

PMC publication ID

4191047

retrieved

1 September 2017

ResearchGate publication ID

266380683

0 references

 

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