Tumor Expression of Cyclin-Dependent Kinase 5 (Cdk5) Is a Prognostic Biomarker and Predicts Outcome of Oxaliplatin-Treated Metastatic Colorectal Cancer Patients (Q90721985)

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scientific article published on 11 October 2019

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English	Tumor Expression of Cyclin-Dependent Kinase 5 (Cdk5) Is a Prognostic Biomarker and Predicts Outcome of Oxaliplatin-Treated Metastatic Colorectal Cancer Patients	scientific article published on 11 October 2019

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31614664%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

Tumor Expression of Cyclin-Dependent Kinase 5 (Cdk5) Is a Prognostic Biomarker and Predicts Outcome of Oxaliplatin-Treated Metastatic Colorectal Cancer Patients (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31614664%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

colorectal cancer

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based on heuristic

inferred from title

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based on heuristic

inferred from title

metastatic colon cancer

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based on heuristic

inferred from title

9

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31614664%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

Eva Martínez-Balibrea

14

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31614664%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

author name string

Vicenç Ruiz de Porras

1

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15 April 2020

Sara Bystrup

2

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15 April 2020

Sara Cabrero-de Las Heras

3

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15 April 2020

Eva Musulén

4

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15 April 2020

Luis Palomero

5

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15 April 2020

Maria Henar Alonso

6

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15 April 2020

Rocio Nieto

7

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15 April 2020

Diego Arango

8

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15 April 2020

Cristina Queralt

10

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15 April 2020

José Luis Manzano

11

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15 April 2020

Laura Layos

12

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15 April 2020

Cristina Bugés

13

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15 April 2020

publication date

11 October 2019

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15 April 2020

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31614664%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

11

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31614664%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

10

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Europe PubMed Central

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15 April 2020

copyright license

Creative Commons Attribution 4.0 International

11 October 2019

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April 2022 Public Data File from Crossref

copyright status

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6826373/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Principles of CDK regulation

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https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin-dependent kinase 5 activity controls cell motility and metastatic potential of prostate cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cdk5 regulates STAT3 activation and cell proliferation in medullary thyroid carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenomic approach for the identification of novel determinants of acquired resistance to oxaliplatin in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased levels of copper efflux transporter ATP7B are associated with poor outcome in colorectal cancer patients receiving oxaliplatin-based chemotherapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of CDK5/p35 in resected patients with non-small cell lung cancer: relation to prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibiting the cyclin-dependent kinase CDK5 blocks pancreatic cancer formation and progression through the suppression of Ras-Ral signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cdk5 kinase regulates the STAT3 transcription factor to prevent DNA damage upon topoisomerase I inhibition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin-dependent kinase 5 is amplified and overexpressed in pancreatic cancer and activated by mutant K-Ras

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Going out of the brain: non-nervous system physiological and pathological functions of Cdk5.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a mutation in the extracellular domain of the Epidermal Growth Factor Receptor conferring cetuximab resistance in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin-dependent kinase 5 modulates STAT3 and androgen receptor activation through phosphorylation of Ser⁷²⁷ on STAT3 in prostate cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CDK5 is essential for TGF-β1-induced epithelial-mesenchymal transition and breast cancer progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant gene expression in mucosa adjacent to tumor reveals a molecular crosstalk in colon cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cdk5 activity in the brain - multiple paths of regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TIGAR regulates DNA damage and repair through pentosephosphate pathway and Cdk5-ATM pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PKM2 Subcellular Localization Is Involved in Oxaliplatin Resistance Acquisition in HT29 Human Colorectal Cancer Cell Lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin-Dependent Kinase 5 (CDK5) Controls Melanoma Cell Motility, Invasiveness, and Metastatic Spread-Identification of a Promising Novel therapeutic target

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The consensus molecular subtypes of colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor cells with KRAS or BRAF mutations or ERK5/MAPK7 amplification are not addicted to ERK5 activity for cell proliferation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cdk5 disruption attenuates tumor PD-L1 expression and promotes antitumor immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CDK5 functions as a tumor promoter in human colorectal cancer via modulating the ERK5-AP-1 axis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31614664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/CANCERS11101540

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31614664%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31614664%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31614664%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

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