IRAK4 in TLR/IL-1R signaling: possible clinical applications (Q80735986)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18286571%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

title

IRAK4 in TLR/IL-1R signaling: possible clinical applications (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18286571%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Xiaoxia Li

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3 January 2020

publication date

1 March 2008

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18286571%20AND%20SRC:MED&resulttype=core&format=json

European Journal of Immunology

3 January 2020

published in

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3 January 2020

volume

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3 January 2020

issue

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3 January 2020

page(s)

614-618

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Essential function for the kinase TAK1 in innate and adaptive immune responses

3 January 2020

cites work

1 reference

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7 January 2021

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

1 reference

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7 January 2021

Interleukin-1 (IL-1)-induced TAK1-dependent Versus MEKK3-dependent NFkappaB activation pathways bifurcate at IL-1 receptor-associated kinase modification

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7 January 2021

Toll-like receptors: critical proteins linking innate and acquired immunity

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7 January 2021

TRAF6 is a signal transducer for interleukin-1

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7 January 2021

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838161

7 January 2021

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

1 reference

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7 January 2021

Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

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7 January 2021

Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling

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7 January 2021

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction

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7 January 2021

Unresponsiveness of MyD88-deficient mice to endotoxin

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7 January 2021

Cutting edge: preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathway

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7 January 2021

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838161

7 January 2021

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

1 reference

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7 January 2021

TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838161

7 January 2021

A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838161

7 January 2021

Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor-mediated immune responses but not in TCR signaling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838161

7 January 2021

IRAK-4 kinase activity is required for interleukin-1 (IL-1) receptor- and toll-like receptor 7-mediated signaling and gene expression

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838161

7 January 2021

IRAK-4 kinase activity-dependent and -independent regulation of lipopolysaccharide-inducible genes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838161

7 January 2021

IRAK4 kinase activity is redundant for interleukin-1 (IL-1) receptor-associated kinase phosphorylation and IL-1 responsiveness

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838161

7 January 2021

The role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signaling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838161

7 January 2021

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

1 reference

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7 January 2021

Pyogenic bacterial infections in humans with IRAK-4 deficiency

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838161

7 January 2021

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838161

7 January 2021

Stabilization of interleukin-2 mRNA by the c-Jun NH2-terminal kinase pathway.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838161

7 January 2021

p38 Mitogen-activated protein kinase-dependent and -independent signaling of mRNA stability of AU-rich element-containing transcripts

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838161

7 January 2021

IRAK-4 mutation (Q293X): rapid detection and characterization of defective post-transcriptional TLR/IL-1R responses in human myeloid and non-myeloid cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838161

7 January 2021

Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838161

7 January 2021

Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopolysaccharide and interleukin-1 in a patient with recurrent bacterial infections

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838161

7 January 2021

Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838161

7 January 2021

Identifiers

DOI

10.1002/EJI.200838161

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18286571%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18286571%20AND%20SRC:MED&resulttype=core&format=json