IRAK4 kinase activity is redundant for interleukin-1 (IL-1) receptor-associated kinase phosphorylation and IL-1 responsiveness (Q40566819)

21 September 2017

title

IRAK4 kinase activity is redundant for interleukin-1 (IL-1) receptor-associated kinase phosphorylation and IL-1 responsiveness (English)

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21 September 2017

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Jean-Laurent Casanova

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21 September 2017

Jinzhong Qin

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21 September 2017

Zhengfan Jiang

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21 September 2017

Youcun Qian

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21 September 2017

Xiaoxia Li

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21 September 2017

language of work or name

English

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publication date

14 April 2004

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Journal of Biological Chemistry

21 September 2017

published in

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21 September 2017

volume

279

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21 September 2017

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21 September 2017

page(s)

26748-26753

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T1/ST2 signaling establishes it as a member of an expanding interleukin-1 receptor family

21 September 2017

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Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol

21 January 2018

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21 January 2018

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IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

21 January 2018

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21 January 2018

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21 January 2018

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

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The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

21 January 2018

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21 January 2018

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Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopolysaccharide and interleukin-1 in a patient with recurrent bacterial infections

21 January 2018

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Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M400785200

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21 September 2017

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