Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. (Q53597468)

16 May 2018

title

Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. (English)

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16 May 2018

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Hans-Uwe Simon

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Leonardo Scapozza

object named as

Leonardo Scapozza

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author name string

Remo Perozzo

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Inès Schmid

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Andrew Ziemiecki

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Thomas Schaffner

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Thomas Brunner

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publication date

24 September 2006

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published in

Nature Cell Biology

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volume

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issue

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page(s)

1124-1132

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Development by self-digestion: molecular mechanisms and biological functions of autophagy

cites work

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Autophagy as a cell death and tumor suppressor mechanism

21 January 2018

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Autophagic proteolysis: control and specificity

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Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8

21 January 2018

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Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

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Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

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Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

21 January 2018

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Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

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The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

21 January 2018

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Neutrophil apoptosis pathways and their modifications in inflammation

21 January 2018

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N-terminal cleavage of bax by calpain generates a potent proapoptotic 18-kDa fragment that promotes bcl-2-independent cytochrome C release and apoptotic cell death

21 January 2018

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Disruption of the murine calpain small subunit gene, Capn4: calpain is essential for embryonic development but not for cell growth and division

21 January 2018

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Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl

21 January 2018

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The role of BH3-only proteins in the immune system

21 January 2018

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Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

21 January 2018

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p53 has a direct apoptogenic role at the mitochondria

21 January 2018

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Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

21 January 2018

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Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.

21 January 2018

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Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3.

21 January 2018

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The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death

21 January 2018

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Mitochondrial translocation of cofilin is an early step in apoptosis induction.

21 January 2018

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Death receptors bind SHP-1 and block cytokine-induced anti-apoptotic signaling in neutrophils

21 January 2018

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Inflammation-associated cell cycle-independent block of apoptosis by survivin in terminally differentiated neutrophils

21 January 2018

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Induction of genes mediating interferon-dependent extracellular trap formation during neutrophil differentiation

21 January 2018

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Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2

21 January 2018

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Protein-tyrosine phosphorylation regulates apoptosis in human eosinophils and neutrophils.

21 January 2018

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Siglec-9 transduces apoptotic and nonapoptotic death signals into neutrophils depending on the proinflammatory cytokine environment

21 January 2018

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Inhibition of platelet-derived growth factor signalling induces autophagy in malignant glioma cells

21 January 2018

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Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference

21 January 2018

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Automatic and quantitative measurement of protein-protein colocalization in live cells.

21 January 2018

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Mitochondrial Release of Pro-apoptotic Proteins

21 January 2018

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Calpain-1 Regulates Bax and Subsequent Smac-dependent Caspase-3 Activation in Neutrophil Apoptosis

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Eosinophils Maintain Their Capacity to Signal and Release Eosinophil Cationic Protein Upon Repetitive Stimulation with the Same Agonist

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inferred from DOI database lookup

7 January 2021

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Efficient transduction of primary human B lymphocytes and nondividing myeloma B cells with HIV-1-derived lentiviral vectors

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inferred from DOI database lookup

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based on heuristic

Identifiers

DOI

10.1038/NCB1482

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16 May 2018

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16 May 2018