Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex. (Q34312488)

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27 December 2019

title

Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex (English)

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27 December 2019

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27 December 2019

J I-Ju Leu

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27 December 2019

Patrick Dumont

series ordinal

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27 December 2019

Michael Hafey

series ordinal

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27 December 2019

Donna L George

series ordinal

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27 December 2019

publication date

11 April 2004

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27 December 2019

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27 December 2019

volume

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27 December 2019

issue

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27 December 2019

page(s)

443-450

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Mechanisms of p53-dependent apoptosis

27 December 2019

cites work

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7 January 2021

Live or let die: the cell's response to p53

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7 January 2021

Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

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7 January 2021

p53 has a direct apoptogenic role at the mitochondria

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7 January 2021

The codon 72 polymorphic variants of p53 have markedly different apoptotic potential

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7 January 2021

Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription

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7 January 2021

Is p53 polymorphism maintained by natural selection?

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7 January 2021

The Bcl2 family: regulators of the cellular life-or-death switch

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7 January 2021

Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

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7 January 2021

Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression

1 reference

7 January 2021

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

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7 January 2021

VDAC2 inhibits BAK activation and mitochondrial apoptosis

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7 January 2021

Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis

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7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

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7 January 2021

DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells

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7 January 2021

BCL-2 Selectively Interacts with the BID-induced Open Conformer of BAK, Inhibiting BAK Auto-oligomerization

1 reference

7 January 2021

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

1 reference

7 January 2021

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

1 reference

7 January 2021

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

1 reference

7 January 2021

MCL-1, a member of the BLC-2 family, is induced rapidly in response to signals for cell differentiation or death, but not to signals for cell proliferation

1 reference

7 January 2021

MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain

1 reference

7 January 2021

MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis

1 reference

7 January 2021

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

1 reference

7 January 2021

A transactivation-deficient mouse model provides insights into Trp53 regulation and function

1 reference

7 January 2021

Isolation and subfractionation of mitochondria from animal cells and tissue culture lines

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7 January 2021

Efficient folding of proteins with multiple disulfide bonds in the Escherichia coli cytoplasm

1 reference

7 January 2021

Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations

1 reference

7 January 2021