Rapamycin reduces hybridoma cell death and enhances monoclonal antibody production (Q43635599)

25 November 2017

title

Rapamycin reduces hybridoma cell death and enhances monoclonal antibody production (English)

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25 November 2017

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Balcarcel RR

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25 November 2017

Stephanopoulos G

series ordinal

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25 November 2017

publication date

1 January 2001

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Biotechnology and Bioengineering

25 November 2017

published in

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25 November 2017

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25 November 2017

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25 November 2017

page(s)

1-10

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The 5' terminal oligopyrimidine tract confers translational control on TOP mRNAs in a cell type- and sequence context-dependent manner.

25 November 2017

cites work

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In pursuit of the optimal fed-batch process for monoclonal antibody production

21 January 2018

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Target of rapamycin (TOR): balancing the opposing forces of protein synthesis and degradation

21 January 2018

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Ribosomal S6 kinase signaling and the control of translation

21 January 2018

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Metabolic flux analysis of hybridoma continuous culture steady state multiplicity

21 January 2018

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Molecular regulation of cell-cycle progression and apoptosis in mammalian cells: implications for biotechnology

21 January 2018

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Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins

21 January 2018

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Understanding and controlling the cell cycle with natural products

21 January 2018

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Rapamycin inhibits didemnin B-induced apoptosis in human HL-60 cells: evidence for the possible involvement of FK506-binding protein 25

21 January 2018

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Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity

21 January 2018

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Establishment of an apoptosis-resistant and growth-controllable cell line by transfecting with inducible antisense c-Jun gene.

21 January 2018

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Cell cycle model for growth rate and death rate in continuous suspension hybridoma cultures.

21 January 2018

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Control of ribosomal protein gene expression

21 January 2018

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Effect of dilution rate on growth, productivity, cell cycle and size, and shear sensitivity of a hybridoma cell in a continuous culture

21 January 2018

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Cell cycle progression and proliferation despite 4BP-1 dephosphorylation

21 January 2018

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Genetically engineering mammalian cell lines for increased viability and productivity

21 January 2018

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Signal transduction pathways that regulate eukaryotic protein synthesis

21 January 2018

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Effect of insulin stimulation on the proliferation and death of Chinese hamster ovary cells

21 January 2018

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Prevention of hybridoma cell death by bcl-2 during suboptimal culture conditions

21 January 2018

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Opposite translational control of GLUT1 and GLUT4 glucose transporter mRNAs in response to insulin. Role of mammalian target of rapamycin, protein kinase b, and phosphatidylinositol 3-kinase in GLUT1 mRNA translation

21 January 2018

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Insulin regulation of glucose-6-phosphate dehydrogenase gene expression is rapamycin-sensitive and requires phosphatidylinositol 3-kinase

21 January 2018

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The economics of ribosome biosynthesis in yeast

21 January 2018

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Translational induction of the c-myc oncogene via activation of the FRAP/TOR signalling pathway

21 January 2018

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Rapamune® (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression

21 January 2018

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Mechanisms and kinetics of monoclonal antibody synthesis and secretion in synchronous and asynchronous hybridoma cell cultures

21 January 2018

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Apoptosis in batch cultures of Chinese hamster ovary cells

21 January 2018

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The polyadenylation inhibitor cordycepin (3'dA) causes a decline in c-MYC mRNA levels without affecting c-MYC protein levels

21 January 2018

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Effects of rapamycin on apoptosis of rheumatoid synovial cells

21 January 2018

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Rapamycin, a potent immunosuppressive drug, causes programmed cell death in B lymphoma cells

21 January 2018

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Cell cycle model for antibody production kinetics

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/BIT.1020

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25 November 2017

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