Endocrine disruptors provoke differential modulatory responses on androgen receptor and pregnane and xenobiotic receptor: potential implications in metabolic disorders (Q42911316)

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scientific article published on September 10, 2010

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English	Endocrine disruptors provoke differential modulatory responses on androgen receptor and pregnane and xenobiotic receptor: potential implications in metabolic disorders	scientific article published on September 10, 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

Endocrine disruptors provoke differential modulatory responses on androgen receptor and pregnane and xenobiotic receptor: potential implications in metabolic disorders (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

endocrine disruptor

1 reference

based on heuristic

inferred from title

author name string

Nagendra Kumar Chaturvedi

1

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

Sanjay Kumar

2

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

Seema Negi

3

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

Rakesh K. Tyagi

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20830510

10 July 2024

language of work or name

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20830510

10 July 2024

publication date

10 September 2010

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

full work available at URL

http://link.springer.com/content/pdf/10.1007/s11010-010-0583-6.pdf

1 reference

10.1007/S11010-010-0583-6

https://api.crossref.org/works/10.1007/S11010-010-0583-6

10 July 2024

http://link.springer.com/article/10.1007/s11010-010-0583-6/fulltext.html

1 reference

10.1007/S11010-010-0583-6

https://api.crossref.org/works/10.1007/S11010-010-0583-6

10 July 2024

http://link.springer.com/content/pdf/10.1007/s11010-010-0583-6

1 reference

10.1007/S11010-010-0583-6

https://api.crossref.org/works/10.1007/S11010-010-0583-6

10 July 2024

Molecular and Cellular Biochemistry

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

345

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

1-2

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

291-308

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

Three's company: two or more unrelated receptors pair with the same ligand

1 reference

https://api.crossref.org/works/10.1007%2FS11010-010-0583-6

21 January 2018

Mouse liver cytochrome P-450 (P-450IIIAM1): its cDNA cloning and inducibility by dexamethasone

1 reference

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21 January 2018

TBP dynamics in living human cells: constitutive association of TBP with mitotic chromosomes

1 reference

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The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4

1 reference

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A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides

1 reference

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12 December 2020

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Cross-talk between androgen receptor and pregnane and xenobiotic receptor reveals existence of a novel modulatory action of anti-androgenic drugs

1 reference

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12 December 2020

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Role of exposure to environmental chemicals in the developmental basis of disease and dysfunction

1 reference

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12 December 2020

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Cotransfection assays and steroid receptor biology

1 reference

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12 December 2020

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Pregnane X Receptor (PXR) expression in colorectal cancer cells restricts irinotecan chemosensitivity through enhanced SN-38 glucuronidation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

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The nuclear receptors constitutive androstane receptor and pregnane X receptor cross-talk with hepatic nuclear factor 4alpha to synergistically activate the human CYP2C9 promoter

1 reference

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Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man.

1 reference

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12 December 2020

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Epigenetics: a landscape takes shape

1 reference

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12 December 2020

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Activation of the steroid and xenobiotic receptor, SXR, induces apoptosis in breast cancer cells

1 reference

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12 December 2020

based on heuristic

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Stabilization of androgen receptor protein is induced by agonist, not by antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

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Intranuclear organization and function of the androgen receptor

1 reference

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12 December 2020

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Endocrine disrupting contaminants--beyond the dogma

1 reference

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12 December 2020

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High-throughput fluorescence microscopy for systems biology

1 reference

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12 December 2020

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Identification of the brominated flame retardant 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane as an androgen agonist.

1 reference

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12 December 2020

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Pathways of endocrine disruption during male sexual differentiation and masculinization

1 reference

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12 December 2020

based on heuristic

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Environmental xenobiotics and nuclear receptors--interactions, effects and in vitro assessment.

1 reference

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12 December 2020

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The dietary isothiocyanate sulforaphane is an antagonist of the human steroid and xenobiotic nuclear receptor.

1 reference

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12 December 2020

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Epigenetic transgenerational actions of endocrine disruptors and male fertility

1 reference

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12 December 2020

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QSAR study of natural, synthetic and environmental endocrine disrupting compounds for binding to the androgen receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

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The role of xenoestrogenic compounds in the development of breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

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Screening for androgen receptor activities in 253 industrial chemicals by in vitro reporter gene assays using AR-EcoScreen cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

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A high-content glucocorticoid receptor translocation assay for compound mechanism-of-action evaluation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

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Dynamics of subcellular compartmentalization of steroid receptors in living cells as a strategic screening method to determine the biological impact of suspected endocrine disruptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

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The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

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Clofibrate and perfluorodecanoate both upregulate the expression of the pregnane X receptor but oppositely affect its ligand-dependent induction on cytochrome P450 3A23.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

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Dynamics of intracellular movement and nucleocytoplasmic recycling of the ligand-activated androgen receptor in living cells

1 reference

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12 December 2020

based on heuristic

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St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

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Androgen receptor corepressors: an overview

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

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Antiandrogenic effects in short-term in vivo studies of the fungicide fenarimol.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

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Effects of environmental antiandrogens on reproductive development in experimental animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

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Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and localization of androgen receptor-interacting protein-4 in the testis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assays for mitotic chromosome condensation in live yeast and mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human CYP3A subfamily: practical considerations

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Androgen receptor: structural domains and functional dynamics after ligand-receptor interaction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Environmental xenoestrogens, antiandrogens and disorders of male sexual differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligands have various potential effects on the degradation of pregnane X receptor by proteasome

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Androgen receptor structural and functional elements: role and regulation in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AR inhibitors identified by high-throughput microscopy detection of conformational change and subcellular localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenerational epigenetic programming of the embryonic testis transcriptome

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pregnane X receptor and natural products: beyond drug-drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular localization and nucleocytoplasmic trafficking of steroid receptors: an overview

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Are problems with male reproductive health caused by endocrine disruption?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipopolysaccharide treatment downregulates the expression of the pregnane X receptor, cyp3a11 and mdr1a genes in mouse placenta

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental exposure to environmental endocrine disruptors: consequences within the ovary and on female reproductive function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiandrogens: selective androgen receptor modulators

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Androgen receptor functional analyses by high throughput imaging: determination of ligand, cell cycle, and mutation-specific effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Health risks and benefits of bis(4-chlorophenyl)-1,1,1-trichloroethane (DDT).

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endocrine disruptors and human health: is there a problem

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-resolution, high-throughput microscopy analyses of nuclear receptor and coregulator function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogens and antiestrogens activate hPXR.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonist-mediated docking of androgen receptor onto the mitotic chromatin platform discriminates intrinsic mode of action of prostate cancer drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endocrine disruptors: a new scientific role for clinical pharmacologists? Impact on human health, wildlife, and the environment

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human pregnane X receptor and resistance to chemotherapy in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear xenobiotic receptor pregnane X receptor locks corepressor silencing mediator for retinoid and thyroid hormone receptors (SMRT) onto the CYP24A1 promoter to attenuate vitamin D3 activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic drug transporters and nuclear receptors: regulation by therapeutic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and potential roles of pregnane X receptor in endometrial cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shuttling components of nuclear import machinery involved in nuclear translocation of steroid receptors exit nucleus via exportin-1/CRM-1* independent pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pregnane X receptor: predicting and preventing drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xenoreceptors CAR and PXR activation and consequences on lipid metabolism, glucose homeostasis, and inflammatory response.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down-regulation of pregnane X receptor contributes to cell growth inhibition and apoptosis by anticancer agents in endometrial cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interplay of pregnane X receptor with other nuclear receptors on gene regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of drug metabolism by blocking the activation of nuclear receptors by ketoconazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nuclear xenobiotic receptor pregnane X receptor: recent insights and new challenges

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pregnane X receptor: promiscuous regulator of detoxification pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Computational discovery of novel low micromolar human pregnane X receptor antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional induction of CYP3A4 by o,p'-DDT in HepG2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PXR and CAR: nuclear receptors which play a pivotal role in drug disposition and chemical toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The subnuclear three-dimensional image analysis of androgen receptor fused to green fluorescence protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetic regulation and downstream targets of the Rhox5 homeobox gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steroid and xenobiotic receptor in human esophageal squamous cell carcinoma: a potent prognostic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective suppressions of human CYP3A forms, CYP3A5 and CYP3A7, by troglitazone in HepG2 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pregnane and Xenobiotic Receptor (PXR/SXR) resides predominantly in the nuclear compartment of the interphase cell and associates with the condensed chromosomes during mitosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CAR and PXR: xenosensors of endocrine disrupters?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Environmental antiandrogens: developmental effects, molecular mechanisms, and clinical implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetics and cancer: towards an evaluation of the impact of environmental and dietary factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endocrine disruption for endocrinologists (and others).

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Testosterone down-regulates ornithine aminotransferase gene and up-regulates arginase II and ornithine decarboxylase genes for polyamines synthesis in the murine kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation and induction of CYP3A11, CYP3A13 and CYP3A25 in C57BL/6J mouse liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elucidating the 'Jekyll and Hyde' nature of PXR: the case for discovering antagonists or allosteric antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New modes of action for endocrine-disrupting chemicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expanding the roles for pregnane X receptor in cancer: proliferation and drug resistance in ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential posttranscriptional regulation of androgen receptor gene expression by androgen in prostate and breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20830510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11010-010-0583-6

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

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