2-(Maleimidomethyl)-1,3-Dioxanes (MD): a Serum-Stable Self-hydrolysable Hydrophilic Alternative to Classical Maleimide Conjugation (Q42372509)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27501860%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

2-(Maleimidomethyl)-1,3-Dioxanes (MD): a Serum-Stable Self-hydrolysable Hydrophilic Alternative to Classical Maleimide Conjugation (English)

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20 March 2020

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20 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27501860%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Igor Dovgan

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20 March 2020

Oleksandr Koniev

series ordinal

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20 March 2020

language of work or name

English

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publication date

9 August 2016

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20 March 2020

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20 March 2020

volume

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20 March 2020

page(s)

30835

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Creative Commons Attribution 4.0 International

20 March 2020

start time

9 August 2016

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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Site-Specific Conjugation of Monomethyl Auristatin E to Anti-CD30 Antibodies Improves Their Pharmacokinetics and Therapeutic Index in Rodent Models

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Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates.

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29 May 2018

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Determination of urinary Tamm-Horsfall protein by ELISA using a maleimide method for enzyme-antibody conjugation

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Conjugation of Glucose Oxidase from Aspergillus niger and Rabbit Antibodies Using N-Hydroxysuccinimide Ester of N-(4-Carboxycyclohexylmethyl)-Maleimide

29 May 2018

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Long-term stabilization of maleimide-thiol conjugates

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Characterization of the drug-to-antibody ratio distribution for antibody-drug conjugates in plasma/serum.

17 August 2018

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Antibody-maytansinoid conjugates are activated in targeted cancer cells by lysosomal degradation and linker-dependent intracellular processing.

17 August 2018

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Self-hydrolyzing maleimides improve the stability and pharmacological properties of antibody-drug conjugates

17 August 2018

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https://api.crossref.org/works/10.1038%2FSREP30835

Use of Normal IgG and its Fragments to Lower the Non-Specific Binding of Fab'-Enzyme Conjugates in Sandwich Enzyme Immunoassay

21 January 2018

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Comparison of four bifunctional reagents for coupling peptides to proteins and the effect of the three moieties on the immunogenicity of the conjugates

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/27501860

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Selective irreversible chemical tagging of cysteine with 3-arylpropiolonitriles

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PubMed

https://pubmed.ncbi.nlm.nih.gov/27501860

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Location matters: site of conjugation modulates stability and pharmacokinetics of antibody drug conjugates

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27501860

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP30835

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27501860%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27501860%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PubMed publication ID

27501860

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27501860%20AND%20SRC:MED&resulttype=core&format=json