Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence (Q41872392)

13 October 2017

Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence (English)

1 reference

Tet methylcytosine dioxygenase 2

13 October 2017

1 reference

GOA release 2020-03-11

author name string

Cheng Li

1 reference

13 October 2017

Yahui Lan

1 reference

13 October 2017

Lianna Schwartz-Orbach

1 reference

13 October 2017

Evgenia Korol

1 reference

13 October 2017

Mamta Tahiliani

1 reference

13 October 2017

Todd Evans

1 reference

13 October 2017

Mary G Goll

1 reference

13 October 2017

language of work or name

1 reference

5 August 2015

1 reference

13 October 2017

1 reference

13 October 2017

1 reference

13 October 2017

1 reference

13 October 2017

1133-1143

1 reference

describes a project that uses

13 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4545447/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Gata2b is a restricted early regulator of hemogenic endothelium in the zebrafish embryo

5 June 2018

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Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems

5 June 2018

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Reverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish.

5 June 2018

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5 June 2018

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TET proteins and 5-methylcytosine oxidation in hematological cancers

5 June 2018

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Critical role of Tet3 in neural progenitor cell maintenance and terminal differentiation

5 June 2018

1 reference

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Loss of Tet enzymes compromises proper differentiation of embryonic stem cells

5 June 2018

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TET2 deficiency inhibits mesoderm and hematopoietic differentiation in human embryonic stem cells.

5 June 2018

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Notch signaling genes: myogenic DNA hypomethylation and 5-hydroxymethylcytosine

5 June 2018

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TET2 plays an essential role in erythropoiesis by regulating lineage-specific genes via DNA oxidative demethylation in a zebrafish model

5 June 2018

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Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis

5 June 2018

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Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation

5 June 2018

1 reference

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Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo

5 June 2018

1 reference

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The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases

5 June 2018

1 reference

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TET enzymes, TDG and the dynamics of DNA demethylation.

5 June 2018

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Blood flow changes coincide with cellular rearrangements during blood vessel pruning in zebrafish embryos

5 June 2018

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TET1 plays an essential oncogenic role in MLL-rearranged leukemia

5 June 2018

1 reference

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Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells

5 June 2018

1 reference

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Sperm, but not oocyte, DNA methylome is inherited by zebrafish early embryos

5 June 2018

1 reference

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Reprogramming the maternal zebrafish genome after fertilization to match the paternal methylation pattern

5 June 2018

1 reference

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Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.

5 June 2018

1 reference

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Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development

5 June 2018

1 reference

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Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition

5 June 2018

1 reference

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In vivo genome editing using a high-efficiency TALEN system

5 June 2018

1 reference

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TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction

5 June 2018

1 reference

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Tet2 disruption leads to enhanced self-renewal and altered differentiation of fetal liver hematopoietic stem cells

5 June 2018

1 reference

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Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation

5 June 2018

1 reference

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Evaluation and application of modularly assembled zinc-finger nucleases in zebrafish

5 June 2018

1 reference

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The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

5 June 2018

1 reference

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Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice

5 June 2018

1 reference

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Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

5 June 2018

1 reference

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Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Haematopoietic stem cells derive directly from aortic endothelium during development

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Hematopoietic stem cell development is dependent on blood flow.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Biomechanical forces promote embryonic haematopoiesis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Foxn4 directly regulates tbx2b expression and atrioventricular canal formation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

High-resolution in situ hybridization to whole-mount zebrafish embryos

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

The zebrafish lysozyme C promoter drives myeloid-specific expression in transgenic fish

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Hematopoietic stem cell fate is established by the Notch-Runx pathway

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

EUKARYOTIC CYTOSINE METHYLTRANSFERASES

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Approaches for the sequence-specific knockdown of mRNA.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Haploinsufficiency, but not defective paternal 5mC oxidation, accounts for the developmental defects of maternal Tet3 knockouts

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Hemogenic endothelium specification and hematopoietic stem cell maintenance employ distinct Scl isoforms.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

TET2 is essential for survival and hematopoietic stem cell homeostasis

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

5-hydroxymethyl-cytosine enrichment of non-committed cells is not a universal feature of vertebrate development.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Targeted gene disruption in somatic zebrafish cells using engineered TALENs

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

Blood stem cells emerge from aortic endothelium by a novel type of cell transition.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23).

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4545447

18 August 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/26257178

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELREP.2015.07.025

1 reference

13 October 2017

1 reference

13 October 2017

PubMed publication ID

26257178

1 reference