Novel 2'-substituted, 3'-deoxy-phosphatidyl-myo-inositol analogues reduce drug resistance in human leukaemia cell lines with an activated phosphoinositide 3-kinase/Akt pathway (Q40492173)

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English	Novel 2'-substituted, 3'-deoxy-phosphatidyl-myo-inositol analogues reduce drug resistance in human leukaemia cell lines with an activated phosphoinositide 3-kinase/Akt pathway	scientific article

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scholarly article

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Europe PubMed Central

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21 September 2017

Novel 2'-substituted, 3'-deoxy-phosphatidyl-myo-inositol analogues reduce drug resistance in human leukaemia cell lines with an activated phosphoinositide 3-kinase/Akt pathway (English)

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Europe PubMed Central

PubMed publication ID

21 September 2017

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Pier Luigi Tazzari

2

object named as

Pier Luigi Tazzari

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21 September 2017

author name string

Giovanna Tabellini

1

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21 September 2017

Roberta Bortul

3

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21 September 2017

Anna Maria Billi

4

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21 September 2017

Roberto Conte

5

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21 September 2017

Lucia Manzoli

6

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21 September 2017

Lucio Cocco

7

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21 September 2017

Alberto M Martelli

8

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21 September 2017

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publication date

1 August 2004

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21 September 2017

British Journal of Haematology

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21 September 2017

126

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21 September 2017

4

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21 September 2017

574-582

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21 September 2017

Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-kappaB activation and cFLIP(L) up-regulation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

Ten years of protein kinase B signalling: a hard Akt to follow

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

The phosphoinositide 3-kinase/Akt pathway regulates cell cycle progression of HL60 human leukemia cells through cytoplasmic relocalization of the cyclin-dependent kinase inhibitor p27(Kip1) and control of cyclin D1 expression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

Specificity and mechanism of action of some commonly used protein kinase inhibitors

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

PI3K/Akt and apoptosis: size matters

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

Phosphatidylinositol-3 kinase inhibitors enhance the anti-leukemia effect of STI571.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

Novel PI analogues selectively block activation of the pro-survival serine/threonine kinase Akt.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

Separation of PP2A core enzyme and holoenzyme with monoclonal antibodies against the regulatory A subunit: abundant expression of both forms in cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

Akt2, phosphatidylinositol 3-kinase, and PTEN are in lipid rafts of intestinal cells: role in absorption and differentiation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

Protein phosphatase 2A-linked and -unlinked caspase-dependent pathways for downregulation of Akt kinase triggered by 4-hydroxynonenal

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

A novel immunosuppressive agent FTY720 induced Akt dephosphorylation in leukemia cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

Constitutive phosphorylation of Akt/PKB protein in acute myeloid leukemia: its significance as a prognostic variable

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

The protein kinase B/Akt signalling pathway in human malignancy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

Sensitisation of HL60 human leukaemic cells to cytotoxic drug-induced apoptosis by inhibition of PI3-kinase survival signals.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

SH2-containing inositol phosphatase 2 predominantly regulates Akt2, and not Akt1, phosphorylation at the plasma membrane in response to insulin in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

Novel protein kinases in pancreatic cell growth and cancer

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

PTEN: from pathology to biology

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

Activation of the PI3K/Akt pathway and chemotherapeutic resistance

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

Survival of acute myeloid leukemia cells requires PI3 kinase activation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.05073.X

21 January 2018

Identifiers

10.1111/J.1365-2141.2004.05073.X

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

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