Stimulation of protein synthesis, eukaryotic translation initiation factor 4E phosphorylation, and PHAS-I phosphorylation by insulin requires insulin receptor substrate 1 and phosphatidylinositol 3-kinase (Q40018987)

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scientific article published on June 1996

Language	Label	Description	Also known as
English	Stimulation of protein synthesis, eukaryotic translation initiation factor 4E phosphorylation, and PHAS-I phosphorylation by insulin requires insulin receptor substrate 1 and phosphatidylinositol 3-kinase	scientific article published on June 1996

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Stimulation of protein synthesis, eukaryotic translation initiation factor 4E phosphorylation, and PHAS-I phosphorylation by insulin requires insulin receptor substrate 1 and phosphatidylinositol 3-kinase (English)

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

phosphorylation

1 reference

based on heuristic

inferred from title

author name string

R Mèndez

1

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

M G Myers

2

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

M F White

3

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

R E Rhoads

4

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

language of work or name

0 references

publication date

1 June 1996

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Europe PubMed Central

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16 September 2017

Molecular and Cellular Biology

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Europe PubMed Central

PMC publication ID

16 September 2017

16

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

6

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

2857-2864

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Repression of cap-dependent translation by 4E-binding protein 1: competition with p220 for binding to eukaryotic initiation factor-4E

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

The insulin signaling system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

Nck associates with the SH2 domain-docking protein IRS-1 in insulin-stimulated cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

Role of IRS-1-GRB-2 complexes in insulin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

Involvement of phosphoinositide 3-kinase in insulin- or IGF-1-induced membrane ruffling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family

1 reference

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22 September 2017

Overproduction of ornithine decarboxylase caused by relief of translational repression is associated with neoplastic transformation.

1 reference

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22 September 2017

Phosphorylation of PHAS-I by mitogen-activated protein (MAP) kinase. Identification of a site phosphorylated by MAP kinase in vitro and in response to insulin in rat adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

Chromatographic resolution of in vivo phosphorylated and nonphosphorylated eukaryotic translation initiation factor eIF-4E: increased cap affinity of the phosphorylated form

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins

1 reference

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22 September 2017

Insulin receptor substrate-1 mediates phosphatidylinositol 3'-kinase and p70S6k signaling during insulin, insulin-like growth factor-1, and interleukin-4 stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

1 reference

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22 September 2017

Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation

1 reference

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22 September 2017

The paradoxical regulation of protein phosphorylation in insulin action.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids

1 reference

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22 September 2017

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

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22 September 2017

Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor

1 reference

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22 September 2017

Role of IRS-2 in insulin and cytokine signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

Eukaryotic Translation Initiation Factor 4E Regulates Expression of Cyclin D1 at Transcriptional and Post-transcriptional Levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

Mapping of functional domains in eukaryotic protein synthesis initiation factor 4G (eIF4G) with picornaviral proteases. Implications for cap-dependent and cap-independent translational initiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

The Translation Initiation Factor eIF-4E Binds to a Common Motif Shared by the Translation Factor eIF-4γ and the Translational Repressors 4E-Binding Proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

cAMP- and rapamycin-sensitive regulation of the association of eukaryotic initiation factor 4E and the translational regulator PHAS-I in aortic smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

Control of PHAS-I by insulin in 3T3-L1 adipocytes. Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen-activated protein kinase-independent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

Mutations of the platelet-derived growth factor receptor that cause a loss of ligand-induced conformational change, subtle changes in kinase activity, and impaired ability to stimulate DNA synthesis

1 reference

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22 September 2017

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

1 reference

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The cell cycle: myths and realities

1 reference

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22 September 2017

Activation of phosphatidylinositol 3-kinase by insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

22 September 2017

Overexpression of eukaryotic protein synthesis initiation factor 4E in HeLa cells results in aberrant growth and morphology

1 reference

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22 September 2017

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

1 reference

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22 September 2017

Polypyrimidine tracts and their binding proteins: regulatory sites for posttranscriptional modulation of gene expression

1 reference

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25 September 2017

Regulation of eukaryotic protein synthesis by initiation factors.

1 reference

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The mechanism by which epidermal growth factor inhibits glycogen synthase kinase 3 in A431 cells

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25 September 2017

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

1 reference

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Insulin receptor signaling is augmented by antisense inhibition of the protein tyrosine phosphatase LAR.

1 reference

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25 September 2017

IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells

1 reference

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17 June 2018

Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin.

1 reference

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17 June 2018

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

1 reference

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17 June 2018

PHAS-I as a link between mitogen-activated protein kinase and translation initiation

1 reference

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17 June 2018

Mechanism of differential regulation of IL-2 in murine Th1 and Th2 T cell subsets. 1. Induction of IL-2 transcription in Th2 cells by up-regulation of transcription factors with the protein synthesis initiation factor 4E.

1 reference

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Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3.

1 reference

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Translational regulation of the mammalian growth-related protein P23: involvement of eIF-4E.

1 reference

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17 June 2018

Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase.

1 reference

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17 June 2018

Dephosphorylation of insulin receptor substrate 1 by the tyrosine phosphatase PTP2C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

17 June 2018

Differential stimulation of phosphorylation of initiation factors eIF-4F, eIF-4B, eIF-3, and ribosomal protein S6 by insulin and phorbol esters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231278

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Insulin induction of ornithine decarboxylase. Importance of mRNA secondary structure and phosphorylation of eucaryotic initiation factors eIF-4B and eIF-4E.

1 reference

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17 June 2018

Translational control of ornithine aminotransferase. Modulation by initiation factor eIF-4E.

1 reference

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17 June 2018

Effects of insulin and phorbol esters on subcellular distribution of protein kinase C isoforms in rat adipocytes

1 reference

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Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.

1 reference

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Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction

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Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

1 reference

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20 August 2018

Dissociation of pp70 ribosomal protein S6 kinase from insulin-stimulated glucose transport in 3T3-L1 adipocytes

1 reference

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On the mechanism of cytosolic phospholipase A2 activation in CHO cells carrying somatostatin receptor: wortmannin-sensitive pathway to activate mitogen-activated protein kinase

1 reference

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Phosphorylation of eukaryotic protein synthesis initiation factor 4E at Ser-209

1 reference

https://pubmed.ncbi.nlm.nih.gov/8649395

12 December 2020

based on heuristic

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Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8649395

12 December 2020

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Casein kinase II is implicated in the regulation of heme-controlled translational inhibitor of reticulocyte lysates

1 reference

https://pubmed.ncbi.nlm.nih.gov/8649395

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based on heuristic

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Regulation of protein synthesis by insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8649395

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Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

1 reference

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Identifiers

10.1128/MCB.16.6.2857

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

release_ku6e7fio5ffztd5jq6cbjjd5ou

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24 November 2022

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

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