The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote (Q41437636)

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scientific article published on October 1994

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English	The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote	scientific article published on October 1994

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scholarly article

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29 October 2019

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf (English)

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29 October 2019

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skeletal muscle cell

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based on heuristic

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based on heuristic

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2

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29 October 2019

author name string

D A Cross

1

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29 October 2019

J R Vandenheede

3

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29 October 2019

H E McDowell

4

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29 October 2019

H S Hundal

5

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29 October 2019

P Cohen

6

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29 October 2019

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publication date

1 October 1994

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29 October 2019

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6

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Biochemical Journal

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29 October 2019

303 ( Pt 1)

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29 October 2019

21-26

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29 October 2019

Insulin-mediated effect on the activity of UDPG-glycogen transglucosylase of muscle

1 reference

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1 October 2017

Dissection of the protein phosphorylation cascades involved in insulin and growth factor action

1 reference

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1 October 2017

Ras signaling in the activation of glucose transport by insulin

1 reference

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1 October 2017

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

1 reference

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1 October 2017

Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1

1 reference

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1 October 2017

The mechanism by which epidermal growth factor inhibits glycogen synthase kinase 3 in A431 cells

1 reference

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1 October 2017

Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

1 October 2017

Activation of Raf as a result of recruitment to the plasma membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

1 October 2017

Glycogen synthase from rabbit skeletal muscle. Amino acid sequence at the sites phosphorylated by glycogen synthase kinase-3, and extension of the N-terminal sequence containing the site phosphorylated by phosphorylase kinase

1 reference

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1 October 2017

Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II.

1 reference

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1 October 2017

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

1 reference

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1 October 2017

Activation of extracellular signal-regulated kinase, ERK2, by p21ras oncoprotein

1 reference

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1 October 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

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1 October 2017

Identification of insulin-stimulated protein kinase-1 as the rabbit equivalent of rskmo-2. Identification of two threonines phosphorylated during activation by mitogen-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

11 June 2018

Specific association of activated MAP kinase kinase kinase (Raf) with the plasma membranes of ras-transformed retinal cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

11 June 2018

Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

11 June 2018

Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI3-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

11 June 2018

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

11 June 2018

Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

11 June 2018

Regulation of protein phosphatase 1 and 2A activities by insulin during myogenesis in rat skeletal muscle cells in culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

11 June 2018

Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

11 June 2018

Proliferative but not nonproliferative responses to granulocyte colony-stimulating factor are associated with rapid activation of the p21ras/MAP kinase signalling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

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Regulation of protein phosphatase-1G from rabbit skeletal muscle. 2. Catalytic subunit translocation is a mechanism for reversible inhibition of activity toward glycogen-bound substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

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MAP2 kinase and 70K S6 kinase lie on distinct signalling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

11 June 2018

Purification and characterisation of the insulin-stimulated protein kinase from rabbit skeletal muscle; close similarity to S6 kinase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

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Distinct mechanisms for the activation of the RSK kinases/MAP2 kinase/pp90rsk and pp70-S6 kinase signaling systems are indicated by inhibition of protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

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1 reference

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Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

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Identification of multifunctional ATP-citrate lyase kinase as the alpha-isoform of glycogen synthase kinase-3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

11 June 2018

Dissociation of pp70 ribosomal protein S6 kinase from insulin-stimulated glucose transport in 3T3-L1 adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137550

19 August 2018

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1 reference

https://pubmed.ncbi.nlm.nih.gov/7945242

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Insulin induces activation and translocation of protein kinase FA (a multifunctional protein phosphatase activator) in human platelet

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the in vivo phosphorylation state of rabbit skeletal muscle glycogen synthase by fast-atom-bombardment mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein phosphatase-1 and protein phosphatase-2A from rabbit skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin induces activation of kinase FA in membranes and thereby promotes activation of ATP.Mg-dependent phosphatase in adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targetting of protein phosphatase 1 to the sarcoplasmic reticulum of rabbit skeletal muscle by a protein that is very similar or identical to the G subunit that directs the enzyme to glycogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945242

12 December 2020

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inferred from PubMed ID database lookup

Evidence for communication between nerve growth factor and protein tyrosine phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development regulation of the subcellular distribution and glycosylation of GLUT1 and GLUT4 glucose transporters during myogenesis of L6 muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The α-isoform of glycogen synthase kinase-3 from rabbit skeletal muscle is inactivated by p70 S6 kinase or MAP kinase-activated protein kinase-1 in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945242

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based on heuristic

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A specific immunoprecipitation assay for the protein kinase FA/glycogen synthase kinase 3

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945242

12 December 2020

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Characterization of insulin-stimulated seryl/threonyl protein kinases in rat skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945242

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inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3030021

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7945242%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7945242%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7945242%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

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