Two levels of protection for the B cell genome during somatic hypermutation. (Q46755254)

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2 January 2020

title

Two levels of protection for the B cell genome during somatic hypermutation (English)

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2 January 2020

author

Carola Garcia de Vinuesa

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2 January 2020

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2 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18273020%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Man Liu

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2 January 2020

Daniel J Richter

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2 January 2020

Steven H Kleinstein

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2 January 2020

David G Schatz

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2 January 2020

language of work or name

English

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publication date

1 February 2008

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2 January 2020

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2 January 2020

volume

451

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2 January 2020

issue

7180

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2 January 2020

page(s)

841-845

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Molecular mechanisms of antibody somatic hypermutation.

2 January 2020

cites work

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7 January 2021

Mechanisms of chromosomal translocations in B cell lymphomas

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7 January 2021

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes

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7 January 2021

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

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7 January 2021

Somatic hypermutation of the B cell receptor genes B29 (Igbeta, CD79b) and mb1 (Igalpha, CD79a).

1 reference

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7 January 2021

Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction

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7 January 2021

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

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7 January 2021

AID mutates a non-immunoglobulin transgene independent of chromosomal position.

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7 January 2021

Genome-wide somatic hypermutation

1 reference

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7 January 2021

AID in somatic hypermutation and class switch recombination

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7 January 2021

Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora

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7 January 2021

The TATA binding protein, c-Myc and survivin genes are not somatically hypermutated, while Ig and BCL6 genes are hypermutated in human memory B cells.

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7 January 2021

Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation

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7 January 2021

Somatic hypermutation and class switch recombination in Msh6(-/-)Ung(-/-) double-knockout mice

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7 January 2021

The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice

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7 January 2021

The E box motif CAGGTG enhances somatic hypermutation without enhancing transcription

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7 January 2021

Targeting of somatic hypermutation

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7 January 2021

G-rich proto-oncogenes are targeted for genomic instability in B-cell lymphomas.

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7 January 2021

H2AX prevents DNA breaks from progressing to chromosome breaks and translocations

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7 January 2021

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.

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7 January 2021

Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

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7 January 2021

Myc translocations in B cell and plasma cell neoplasms

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7 January 2021

Down-regulation of DNA polymerase beta accompanies somatic hypermutation in human BL2 cell lines

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7 January 2021

What role for AID: mutator, or assembler of the immunoglobulin mutasome?

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7 January 2021

Co-repression of mismatch repair gene expression by hypoxia in cancer cells: role of the Myc/Max network

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7 January 2021

Beyond SHM and CSR: AID and related cytidine deaminases in the host response to viral infection

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7 January 2021

Infection of human B cells with Epstein-Barr virus results in the expression of somatic hypermutation-inducing molecules and in the accrual of oncogene mutations

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7 January 2021

Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobulin and protooncogenes

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7 January 2021

Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium

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7 January 2021

Statistical significance for genomewide studies

1 reference

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7 January 2021

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06547

7 January 2021

MSH2 deficient mice are viable and susceptible to lymphoid tumours

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7 January 2021

Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication

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7 January 2021

Axon growth and guidance genes identify T-dependent germinal centre B cells

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7 January 2021

Transcriptional analysis of the B cell germinal center reaction

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7 January 2021

The lymphochip: a specialized cDNA microarray for the genomic-scale analysis of gene expression in normal and malignant lymphocytes.

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7 January 2021

DBTSS: DataBase of human Transcriptional Start Sites and full-length cDNAs

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7 January 2021

A census of human cancer genes

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7 January 2021

Identification of a potential role for POU2AF1 and BTG4 in the deletion of 11q23 in chronic lymphocytic leukemia.

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7 January 2021

Monitoring and interpreting the intrinsic features of somatic hypermutation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06547

7 January 2021

An SNP map of the human genome generated by reduced representation shotgun sequencing

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https://api.crossref.org/works/10.1038%2FNATURE06547

7 January 2021

Base-calling of automated sequencer traces using phred. II. Error probabilities

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https://api.crossref.org/works/10.1038%2FNATURE06547

7 January 2021

Base-calling of automated sequencer traces using phred. I. Accuracy assessment

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06547

7 January 2021

Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

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7 January 2021

The UCSC Table Browser data retrieval tool

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7 January 2021

The human genome browser at UCSC

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7 January 2021

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

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7 January 2021

Identifiers

DOI

10.1038/NATURE06547

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18273020%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

2 January 2020

1026421044

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Fatcat ID

release_odwxi5zk2rbsxpss3w3owkvn7u

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Fatcat

https://api.fatcat.wiki/v0/release/odwxi5zk2rbsxpss3w3owkvn7u

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18273020%20AND%20SRC:MED&resulttype=core&format=json