Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships (Q46176653)

20 December 2017

title

Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships (English)

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20 December 2017

author name string

Kelly E. Heim

series ordinal

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20 December 2017

Anthony R. Tagliaferro

series ordinal

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20 December 2017

Dennis J. Bobilya

series ordinal

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20 December 2017

publication date

1 October 2002

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20 December 2017

Journal of Nutritional Biochemistry

published in

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20 December 2017

volume

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20 December 2017

issue

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20 December 2017

page(s)

572-584

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20 December 2017

Advances in flavonoid research since 1992.

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Procyanidin content and variation in some commonly consumed foods

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Levels of flavan-3-ols in French wines

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Analysis of phenolic constituents of biological interest in red wines by high-performance liquid chromatography

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Extraction of rutin from buckwheat (Fagopyrum esculentumMoench) seeds and determination by capillary electrophoresis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Occurrence of flavonols in tomatoes and tomato-based products

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Quantitative survey of narirutin, naringin, hesperidin, and neohesperidin in citrus

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Phytoestrogen content of foods--a compendium of literature values

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in the Netherlands

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Inhibition of LDL oxidation by cocoa

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Diet enriched with procyanidins enhances antioxidant activity and reduces myocardial post-ischaemic damage in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Dietary flavonoid intake and risk of cardiovascular disease in postmenopausal women

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Catechin intake might explain the inverse relation between tea consumption and ischemic heart disease: the Zutphen Elderly Study

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Mitochondrial oxidative stress plays a key role in aging and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Oxidative stress promotes the development of transformation: involvement of a potent mutagenic lipid peroxidation product, acrolein

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Mechanism of guanine-specific DNA damage by oxidative stress and its role in carcinogenesis and aging

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Structure-activity relationships of polymethoxyflavones and other flavonoids as inhibitors of non-enzymic lipid peroxidation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Formation of F2-isoprostanes during oxidation of human low-density lipoprotein and plasma by peroxynitrite

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Reactive nitrogen intermediates promote low density lipoprotein oxidation in human atherosclerotic intima

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Peroxynitrite-induced myocardial injury is mediated through matrix metalloproteinase-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Protection against oxidative damage of erythrocyte membrane by the flavonoid quercetin and its relation to iron chelating activity

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Inhibition of glutathione reductase by flavonoids

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Antioxidant ability of various flavonoids against DPPH radicals and LDL oxidation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Structure-activity relationship and classification of flavonoids as inhibitors of xanthine oxidase and superoxide scavengers

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

The chemistry of tea flavonoids

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Characterization of grape procyanidins using high-performance liquid Chromatography/Mass spectrometry and matrix-assisted laser Desorption/Ionization time-of-flight mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

HPLC method for the quantification of procyanidins in cocoa and chocolate samples and correlation to total antioxidant capacity

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Structure-antioxidant activity relationships of flavonoids and phenolic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Dietary flavonoid and isoflavone glycosides are hydrolysed by the lactase site of lactase phlorizin hydrolase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

The small intestine can both absorb and glucuronidate luminal flavonoids

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver beta-glucosidase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Intestinal absorption of luteolin and luteolin 7-O-beta-glucoside in rats and humans

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Bioavailability of phloretin and phloridzin in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Bioavailability of rutin and quercetin in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Intestinal bacterial metabolism of flavonoids and its relation to some biological activities

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

The sugar moiety is a major determinant of the absorption of dietary flavonoid glycosides in man

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Dietary flavonoids: intake, health effects and bioavailability

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Tea and coronary heart disease: the flavonoid quercetin is more bioavailable from rutin in women than in men.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Bioavailabilities of quercetin-3-glucoside and quercetin-4'-glucoside do not differ in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Quercetin glucosides interact with the intestinal glucose transport pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Carbon-14 biolabeling of (+)-catechin and proanthocyanidin oligomers in willow tree cuttings

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

The microbial metabolism of condensed (+)-catechins by rat-caecal microflora

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Decomposition of cocoa procyanidins in the gastric milieu

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Clostridium orbiscindens sp. nov., a human intestinal bacterium capable of cleaving the flavonoid C-ring

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Studies on drug metabolism by use of isotopes XXVII: urinary metabolites of rutin in rats and the role of intestinal microflora in the metabolism of rutin

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Polymeric proanthocyanidins are catabolized by human colonic microflora into low-molecular-weight phenolic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Biotransformation of (-)-epicatechin 3-O-gallate by human intestinal bacteria

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Identification and antioxidant activity of flavonoid metabolites in plasma and urine of eriocitrin-treated rats

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

In vitro biotransformation of flavonoids by rat liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Induction of rat liver cytochrome P450 isoenzymes CYP 1A and CYP 2B by different fungicides, nitrofurans, and quercetin

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Bioflavonoids: selective substrates and inhibitors for cytochrome P450 CYP1A and CYP1B1

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Antioxidative activity of natural products from plants

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Carbon dioxide is the major metabolite of quercetin in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Catechins are bioavailable in men and women drinking black tea throughout the day

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Accumulation of (-)-epicatechin metabolites in rat plasma after oral administration and distribution of conjugation enzymes in rat tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Human metabolism of dietary flavonoids: identification of plasma metabolites of quercetin

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Disposition and metabolism of the flavonoid chrysin in normal volunteers

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Contrasting influences of glucuronidation and O-methylation of epicatechin on hydrogen peroxide-induced cell death in neurons and fibroblasts.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Pharmacokinetics of quercetin from quercetin aglycone and rutin in healthy volunteers

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Influence of a series of natural flavonoids on free radical generating systems and oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Epicatechin in human plasma: in vivo determination and effect of chocolate consumption on plasma oxidation status

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

A dose-response effect from chocolate consumption on plasma epicatechin and oxidative damage

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Relative bioavailability of the antioxidant flavonoid quercetin from various foods in man

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Interactions between flavonoids and proteins: effect on the total antioxidant capacity.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Addition of milk does not affect the absorption of flavonols from tea in man.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Antioxidant and prooxidant behavior of flavonoids: structure-activity relationships

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Flavonoid B-ring chemistry and antioxidant activity: fast reaction kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Peroxynitrite Scavenging by Flavonoids

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Antioxidant and antiradical activities of flavonoids

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Inhibition of peroxynitrite-mediated oxidation of dopamine by flavonoid and phenolic antioxidants and their structural relationships

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Effects of flavonoids on nonenzymatic lipid peroxidation: Structure-activity relationship

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Evaluation of the total peroxyl radical-scavenging capacity of flavonoids: structure-activity relationships

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Structure-activity relationship of flavonoids with superoxide scavenging activity

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

A quantum chemical explanation of the antioxidant activity of flavonoids

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Structure–Activity Relationships for Antioxidant Activities of a Series of Flavonoids in a Liposomal System

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Inhibitory effects of phenolic compounds on CCl4-induced microsomal lipid peroxidation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Inhibitory effect of isoflavones on peroxynitrite-mediated low-density lipoprotein oxidation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Hydrogen bond formation as basis for radical scavenging activity: a structure-activity study of C-methylated dihydrochalcones from Myrica gale and structurally related acetophenones

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Flavonoids as antioxidants: determination of radical-scavenging efficiencies

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Protection against peroxynitrite by cocoa polyphenol oligomers

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Characterization of flavonoid--biomembrane interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Oxygen-radical absorbance capacity assay for antioxidants

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Quantitative structure-activity relationship analysis of phenolic antioxidants

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Antioxidant properties of flavonol glycosides from tea

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Antioxidative activity of quercetin and quercetin monoglucosides in solution and phospholipid bilayers

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Effects of flavonoids on the release of reactive oxygen species by stimulated human neutrophils. Multivariate analysis of structure-activity relationships (SAR)

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Procyanidins from tormentil: fractionation and study of the anti-radical activity towards superoxide anion

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Antioxidant activity and radioprotective effects against chromosomal damage induced in vivo by X-rays of flavan-3-ols (Procyanidins) from grape seeds (Vitis vinifera): comparative study versus other phenolic and organic compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

An evaluation of the antioxidant activity of a standardized grape seed extract, Leucoselect

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Antioxidant therapy--a new therapeutic option for reducing mortality from coronary artery disease

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Antioxidant and iron-chelating activities of the flavonoids catechin, quercetin and diosmetin on iron-loaded rat hepatocyte cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Influence of metal ions on flavonoid protection against asbestos-induced cell injury

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Different antioxidant activities of bioflavonoid rutin in normal and iron-overloading rats

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Anti- and pro-oxidative effects of flavonoids on metal-induced lipid hydroperoxide-dependent lipid peroxidation in cultured hepatocytes loaded with alpha-linolenic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Lipid peroxidation and dna damage induced by morin and naringenin in isolated rat liver nuclei

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

On the ability of four flavonoids, baicilein, luteolin, naringenin, and quercetin, to suppress the Fenton reaction of the iron-ATP complex

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Prooxidant activity of flavonoids: copper-dependent strand breaks and the formation of 8-hydroxy-2'-deoxyguanosine in DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Mechanism of oxidative DNA damage induced by quercetin in the presence of Cu(II).

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

The correlation between active oxygens scavenging and antioxidative effects of flavonoids

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Inhibition of mitochondrial respiration and production of toxic oxygen radicals by flavonoids. A structure-activity study

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Baicalin induces apoptosis via mitochondrial pathway as prooxidant

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

A novel cytotoxic flavonoid glycoside from Physalis angulata

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Antioxidant and pro-oxidant actions of flavonoids: effects on DNA damage induced by nitric oxide, peroxynitrite and nitroxyl anion

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Interaction of flavonoids with ascorbate and determination of their univalent redox potentials: A pulse radiolysis study

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

Catechol O-methyltransferase. 5. Structure-activity relations for inhibition by flavonoids

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

The Relative Antioxidant Activities of Plant-Derived Polyphenolic Flavonoids

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900208-5

7 January 2021

10.1016/S0955-2863(02)00208-5

Identifiers

DOI

1 reference

20 December 2017

1 reference

20 December 2017